Timeline

Francesca Di Nunzio

Head of Structure

10 Nov 2025

event

Groupe de Réflexion SIDA (GRS) meeting: “Mucosal immunity to viruses”

27 Aug 2025

publication

Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle.

01 Mar 2025

publication

[The HIV-1 capsid : a karyopherin-like that enables the virus to traverse nucleoporin condensates and invade the cell nucleus].

01 Jan 2025

publication

In vivo HIV-1 nuclear condensates safeguard against cGAS and license reverse transcription.

13 Aug 2024

publication

Long COVID Syndrome: A Narrative Review on Burden of Age and Vaccination.

23 Jan 2024

project

Etude du mécanisme de persistance à l’état latent du virus de l’immunodéficience humaine dénommé « condensat » : NEWVIRBIO (2023-036)

05 Jan 2024

event

Group de Reflexion SIDA (GRS) seminar: “New insights in the regulation of HIV expression and latency”

01 Jan 2024

publication

Characterization of Nuclear HIV-Induced Membraneless Organelles Through Fluorescence Microscopy.

10 Oct 2023

event

Groupe de Réflexion SIDA (GRS) meeting: “HIV sensing, nuclear import, and latency”

15 Aug 2023

publication

HIV-Induced CPSF6 Condensates.

17 May 2023

event

40 years of HIV science

10 May 2023

publication

Stress-induced condensate switch awakens sleeping viruses.

07 Apr 2023

publication

Biomolecular condensates: insights into early and late steps of the HIV-1 replication cycle.

06 Apr 2023

publication

HIV-induced membraneless organelles orchestrate post-nuclear entry steps.

21 Nov 2022

event

“First live track detection of HIV DNA in Humanized model by single-cell imaging”

02 Nov 2022

event

Groupe de Reflexion SIDA (GRS) meeting: “Role of membraneless organelles in viral replication”

21 Jul 2022

event

Groupe de Reflexion SIDA (GRS) seminar: “Functional and structural studies of the T cell response against two major human viruses: HIV-1 and SARS-CoV-2”

30 Jan 2022

project

Project 3: HIV-1 and nuclear membraneless organelles

30 Jan 2022

project

Project 2: Deciphering the early steps of HIV-1 infection: discovery of a new early step mechanism.

30 Jan 2022

project

Project 1: Ultrastructural conformation states of HIV-1 during the early steps of viral infection

13 Oct 2021

event

Groupe de Réflexion SIDA (GRS) meeting: “The cytoskeleton and viruses”

09 Sep 2021

course

MOOC Viruses and Human Cancers

04 Aug 2021

publication

Membraneless organelles restructured and built by pandemic viruses: HIV-1 and SARS-CoV-2.

20 Jun 2021

publication

The Viral Capsid: A Master Key to Access the Host Nucleus.

10 Feb 2021

publication

The HIV-1 Capsid: From Structural Component to Key Factor for Host Nuclear Invasion.

04 Jan 2021

publication

Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages.

18 May 2020

publication

Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes.

17 Mar 2020

publication

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core.

09 Jan 2019

team

Advanced Molecular Virology

01 Jan 2019

publication

Features of Primary Chronic Headache in Children and Adolescents and Validity of Ichd 3 Criteria.

01 Oct 2018

publication

Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells.

01 Jan 2018

publication

[Host nuclear pore factors: team players of HIV-1 nuclear translocation and integration].

01 Apr 2016

publication

SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.

12 Feb 2016

project

Group for AIDS Research

01 Aug 2015

publication

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal.

06 Mar 2015

publication

Chromatin organization at the nuclear pore favours HIV replication.

08 Jan 2014

publication

Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses.

01 Jan 2014

publication

FlAsH-PALM: super-resolution pointillist imaging with FlAsH-tetracysteine labeling.

26 Dec 2013

publication

New insights in the role of nucleoporins: a bridge leading to concerted steps from HIV-1 nuclear entry until integration.

25 May 2013

publication

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.

01 Jan 2013

publication

TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.

29 May 2012

publication

Superresolution imaging of HIV in infected cells with FlAsH-PALM.

01 May 2012

publication

TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core.

28 Mar 2012

publication

HIV-derived vectors for therapy and vaccination against HIV.

01 Jan 2012

publication

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration.

10 Nov 2011

publication

Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection.

01 Sep 2011

publication

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha.

19 Oct 2009

publication

Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase.

01 Jul 2009

publication

Structural basis for functional tetramerization of lentiviral integrase.

01 Dec 2008

publication

Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors.

01 Dec 2008

publication

Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity.

01 Sep 2007

publication

Transduction of human hematopoietic stem cells by lentiviral vectors pseudotyped with the RD114-TR chimeric envelope glycoprotein.

01 Dec 2006

publication

A little guide for advanced search:

Groupe de Réflexion SIDA (GRS) meeting: “Mucosal immunity to viruses”

Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle.

[The HIV-1 capsid : a karyopherin-like that enables the virus to traverse nucleoporin condensates and invade the cell nucleus].

In vivo HIV-1 nuclear condensates safeguard against cGAS and license reverse transcription.

Long COVID Syndrome: A Narrative Review on Burden of Age and Vaccination.

Etude du mécanisme de persistance à l’état latent du virus de l’immunodéficience humaine dénommé « condensat » : NEWVIRBIO (2023-036)

Group de Reflexion SIDA (GRS) seminar: “New insights in the regulation of HIV expression and latency”

Characterization of Nuclear HIV-Induced Membraneless Organelles Through Fluorescence Microscopy.

Groupe de Réflexion SIDA (GRS) meeting: “HIV sensing, nuclear import, and latency”

HIV-Induced CPSF6 Condensates.

40 years of HIV science

Stress-induced condensate switch awakens sleeping viruses.

Biomolecular condensates: insights into early and late steps of the HIV-1 replication cycle.

HIV-induced membraneless organelles orchestrate post-nuclear entry steps.

“First live track detection of HIV DNA in Humanized model by single-cell imaging”

Groupe de Reflexion SIDA (GRS) meeting: “Role of membraneless organelles in viral replication”

Groupe de Reflexion SIDA (GRS) seminar: “Functional and structural studies of the T cell response against two major human viruses: HIV-1 and SARS-CoV-2”

Project 3: HIV-1 and nuclear membraneless organelles

Project 2: Deciphering the early steps of HIV-1 infection: discovery of a new early step mechanism.

Project 1: Ultrastructural conformation states of HIV-1 during the early steps of viral infection

Groupe de Réflexion SIDA (GRS) meeting: “The cytoskeleton and viruses”

MOOC Viruses and Human Cancers

Membraneless organelles restructured and built by pandemic viruses: HIV-1 and SARS-CoV-2.

The Viral Capsid: A Master Key to Access the Host Nucleus.

The HIV-1 Capsid: From Structural Component to Key Factor for Host Nuclear Invasion.

Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages.

Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes.

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core.

Advanced Molecular Virology

Features of Primary Chronic Headache in Children and Adolescents and Validity of Ichd 3 Criteria.

Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells.

[Host nuclear pore factors: team players of HIV-1 nuclear translocation and integration].

SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.

Group for AIDS Research

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal.

Chromatin organization at the nuclear pore favours HIV replication.

Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses.

FlAsH-PALM: super-resolution pointillist imaging with FlAsH-tetracysteine labeling.

New insights in the role of nucleoporins: a bridge leading to concerted steps from HIV-1 nuclear entry until integration.

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.

TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.

Superresolution imaging of HIV in infected cells with FlAsH-PALM.

TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core.

HIV-derived vectors for therapy and vaccination against HIV.

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration.

Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection.

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha.

Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase.

Structural basis for functional tetramerization of lentiviral integrase.

Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors.

Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity.

Transduction of human hematopoietic stem cells by lentiviral vectors pseudotyped with the RD114-TR chimeric envelope glycoprotein.

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells.