Timeline

Francesca Di Nunzio
Group Leader
13 Sep 2020
project

Early steps of HIV-1 life cycle

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18 May 2020
publication

Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes.

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17 Mar 2020
publication

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core.

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09 Jan 2019
team

Group: Francesca Di Nunzio

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12 Sep 2018
publication

Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells

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31 Jul 2018
publication

[Host nuclear pore factors: team players of HIV-1 nuclear translocation and integration]

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03 Jul 2015
project

Project

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10 Jun 2015
publication

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal

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11 May 2015
team

Molecular Virology and Vaccinology

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06 Mar 2015
publication

Chromatin organization at the nuclear pore favours HIV replication

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01 Jan 2014
publication

FlAsH-PALM: super-resolution pointillist imaging with FlAsH-tetracysteine labeling

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01 Jan 2014
publication

Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses

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27 Nov 2013
publication

TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication

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16 Sep 2013
publication

New insights in the role of nucleoporins: a bridge leading to concerted steps from HIV-1 nuclear entry until integration

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21 Mar 2013
publication

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

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25 Sep 2012
publication

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration

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14 May 2012
publication

Superresolution imaging of HIV in infected cells with FlAsH-PALM

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07 Mar 2012
publication

TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core

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13 Feb 2012
publication

HIV-derived vectors for therapy and vaccination against HIV

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10 Nov 2011
publication

Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection

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06 Jul 2011
publication

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha

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19 Oct 2009
publication

Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase

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17 Jul 2009
publication

Structural basis for functional tetramerization of lentiviral integrase

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23 Sep 2008
publication

Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors

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17 Sep 2008
publication

Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity

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01 Sep 2007
publication

Transduction of human hematopoietic stem cells by lentiviral vectors pseudotyped with the RD114-TR chimeric envelope glycoprotein

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19 Nov 2006
publication

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells

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