Timeline

Francesca Di Nunzio

Group Leader

13 Sep 2020

project

Early steps of HIV-1 life cycle

18 May 2020

publication

Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes.

17 Mar 2020

publication

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core.

09 Jan 2019

team

Group: Francesca Di Nunzio

12 Sep 2018

publication

Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells

31 Jul 2018

publication

[Host nuclear pore factors: team players of HIV-1 nuclear translocation and integration]

03 Jul 2015

project

Project

10 Jun 2015

publication

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal

11 May 2015

team

Molecular Virology and Vaccinology

06 Mar 2015

publication

Chromatin organization at the nuclear pore favours HIV replication

01 Jan 2014

publication

FlAsH-PALM: super-resolution pointillist imaging with FlAsH-tetracysteine labeling

01 Jan 2014

publication

Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses

27 Nov 2013

publication

TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication

16 Sep 2013

publication

New insights in the role of nucleoporins: a bridge leading to concerted steps from HIV-1 nuclear entry until integration

21 Mar 2013

publication

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

25 Sep 2012

publication

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration

14 May 2012

publication

Superresolution imaging of HIV in infected cells with FlAsH-PALM

07 Mar 2012

publication

TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core

13 Feb 2012

publication

HIV-derived vectors for therapy and vaccination against HIV

10 Nov 2011

publication

Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection

06 Jul 2011

publication

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha

19 Oct 2009

publication

Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase

17 Jul 2009

publication

Structural basis for functional tetramerization of lentiviral integrase

23 Sep 2008

publication

Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors

17 Sep 2008

publication

Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity

01 Sep 2007

publication

Transduction of human hematopoietic stem cells by lentiviral vectors pseudotyped with the RD114-TR chimeric envelope glycoprotein

19 Nov 2006

publication

A little guide for advanced search:

Timeline

Early steps of HIV-1 life cycle

Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes.

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core.

Group: Francesca Di Nunzio

Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells

[Host nuclear pore factors: team players of HIV-1 nuclear translocation and integration]

Project

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal

Molecular Virology and Vaccinology

Chromatin organization at the nuclear pore favours HIV replication

FlAsH-PALM: super-resolution pointillist imaging with FlAsH-tetracysteine labeling

Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses

TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication

New insights in the role of nucleoporins: a bridge leading to concerted steps from HIV-1 nuclear entry until integration

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration

Superresolution imaging of HIV in infected cells with FlAsH-PALM

TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core

HIV-derived vectors for therapy and vaccination against HIV

Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha

Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase

Structural basis for functional tetramerization of lentiviral integrase

Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors

Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity

Transduction of human hematopoietic stem cells by lentiviral vectors pseudotyped with the RD114-TR chimeric envelope glycoprotein

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells