Timeline

Francesca Di Nunzio
Head of Structure
21 Nov 2022
event

“First live track detection of HIV DNA in Humanized model by single-cell imaging”

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02 Nov 2022
event

Groupe de Reflexion SIDA (GRS) meeting: “Role of membraneless organelles in viral replication”

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31 Oct 2022
publication

HIV-induced membraneless organelles orchestrate post-nuclear entry steps.

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21 Jul 2022
event

Groupe de Reflexion SIDA (GRS) seminar: “Functional and structural studies of the T cell response against two major human viruses: HIV-1 and SARS-CoV-2”

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30 Jan 2022
project

Project 3: HIV-1 and nuclear membraneless organelles

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30 Jan 2022
project

Project 2: Deciphering the early steps of HIV-1 infection: discovery of a new early step mechanism.

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30 Jan 2022
project

Project 1: Ultrastructural conformation states of HIV-1 during the early steps of viral infection

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13 Oct 2021
event

Groupe de Réflexion SIDA (GRS) meeting: “The cytoskeleton and viruses”

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09 Sep 2021
course

MOOC Viruses and Human Cancers

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04 Aug 2021
publication

Membraneless organelles restructured and built by pandemic viruses: HIV-1 and SARS-CoV-2.

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20 Jun 2021
publication

The Viral Capsid: A Master Key to Access the Host Nucleus.

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10 Feb 2021
publication

The HIV-1 Capsid: From Structural Component to Key Factor for Host Nuclear Invasion.

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04 Jan 2021
publication

Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages.

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18 May 2020
publication

Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes.

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17 Mar 2020
publication

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core.

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09 Jan 2019
team

Advanced Molecular Virology

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12 Sep 2018
publication

Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells.

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31 Jul 2018
publication

[Host nuclear pore factors: team players of HIV-1 nuclear translocation and integration].

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12 Feb 2016
project

Group for AIDS Research

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10 Feb 2016
publication

SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.

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10 Jun 2015
publication

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal.

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06 Mar 2015
publication

Chromatin organization at the nuclear pore favours HIV replication.

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01 Jan 2014
publication

FlAsH-PALM: super-resolution pointillist imaging with FlAsH-tetracysteine labeling.

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01 Jan 2014
publication

Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses

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27 Nov 2013
publication

TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.

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16 Sep 2013
publication

New insights in the role of nucleoporins: a bridge leading to concerted steps from HIV-1 nuclear entry until integration.

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21 Mar 2013
publication

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.

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25 Sep 2012
publication

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration.

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14 May 2012
publication

Superresolution imaging of HIV in infected cells with FlAsH-PALM.

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07 Mar 2012
publication

TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core

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13 Feb 2012
publication

HIV-derived vectors for therapy and vaccination against HIV.

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10 Nov 2011
publication

Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection.

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06 Jul 2011
publication

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha

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19 Oct 2009
publication

Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase

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17 Jul 2009
publication

Structural basis for functional tetramerization of lentiviral integrase

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23 Sep 2008
publication

Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors

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17 Sep 2008
publication

Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity

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01 Sep 2007
publication

Transduction of human hematopoietic stem cells by lentiviral vectors pseudotyped with the RD114-TR chimeric envelope glycoprotein

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19 Nov 2006
publication

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells

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