Timeline

Francesca Di Nunzio

Head of Structure

21 Nov 2022

event

“First live track detection of HIV DNA in Humanized model by single-cell imaging”

02 Nov 2022

event

Groupe de Reflexion SIDA (GRS) meeting: “Role of membraneless organelles in viral replication”

31 Oct 2022

publication

HIV-induced membraneless organelles orchestrate post-nuclear entry steps.

21 Jul 2022

event

Groupe de Reflexion SIDA (GRS) seminar: “Functional and structural studies of the T cell response against two major human viruses: HIV-1 and SARS-CoV-2”

30 Jan 2022

project

Project 3: HIV-1 and nuclear membraneless organelles

30 Jan 2022

project

Project 2: Deciphering the early steps of HIV-1 infection: discovery of a new early step mechanism.

30 Jan 2022

project

Project 1: Ultrastructural conformation states of HIV-1 during the early steps of viral infection

13 Oct 2021

event

Groupe de Réflexion SIDA (GRS) meeting: “The cytoskeleton and viruses”

09 Sep 2021

course

MOOC Viruses and Human Cancers

04 Aug 2021

publication

Membraneless organelles restructured and built by pandemic viruses: HIV-1 and SARS-CoV-2.

20 Jun 2021

publication

The Viral Capsid: A Master Key to Access the Host Nucleus.

10 Feb 2021

publication

The HIV-1 Capsid: From Structural Component to Key Factor for Host Nuclear Invasion.

04 Jan 2021

publication

Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages.

18 May 2020

publication

Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes.

17 Mar 2020

publication

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core.

09 Jan 2019

team

Advanced Molecular Virology

12 Sep 2018

publication

Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells.

31 Jul 2018

publication

[Host nuclear pore factors: team players of HIV-1 nuclear translocation and integration].

12 Feb 2016

project

Group for AIDS Research

10 Feb 2016

publication

SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.

10 Jun 2015

publication

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal.

06 Mar 2015

publication

Chromatin organization at the nuclear pore favours HIV replication.

01 Jan 2014

publication

Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses

01 Jan 2014

publication

FlAsH-PALM: super-resolution pointillist imaging with FlAsH-tetracysteine labeling.

27 Nov 2013

publication

TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.

16 Sep 2013

publication

New insights in the role of nucleoporins: a bridge leading to concerted steps from HIV-1 nuclear entry until integration.

21 Mar 2013

publication

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.

25 Sep 2012

publication

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration.

14 May 2012

publication

Superresolution imaging of HIV in infected cells with FlAsH-PALM.

07 Mar 2012

publication

TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core

13 Feb 2012

publication

HIV-derived vectors for therapy and vaccination against HIV.

10 Nov 2011

publication

Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection.

06 Jul 2011

publication

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha

19 Oct 2009

publication

Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase

17 Jul 2009

publication

Structural basis for functional tetramerization of lentiviral integrase

23 Sep 2008

publication

Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors

17 Sep 2008

publication

Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity

01 Sep 2007

publication

Transduction of human hematopoietic stem cells by lentiviral vectors pseudotyped with the RD114-TR chimeric envelope glycoprotein

19 Nov 2006

publication

A little guide for advanced search:

“First live track detection of HIV DNA in Humanized model by single-cell imaging”

Groupe de Reflexion SIDA (GRS) meeting: “Role of membraneless organelles in viral replication”

HIV-induced membraneless organelles orchestrate post-nuclear entry steps.

Groupe de Reflexion SIDA (GRS) seminar: “Functional and structural studies of the T cell response against two major human viruses: HIV-1 and SARS-CoV-2”

Project 3: HIV-1 and nuclear membraneless organelles

Project 2: Deciphering the early steps of HIV-1 infection: discovery of a new early step mechanism.

Project 1: Ultrastructural conformation states of HIV-1 during the early steps of viral infection

Groupe de Réflexion SIDA (GRS) meeting: “The cytoskeleton and viruses”

MOOC Viruses and Human Cancers

Membraneless organelles restructured and built by pandemic viruses: HIV-1 and SARS-CoV-2.

The Viral Capsid: A Master Key to Access the Host Nucleus.

The HIV-1 Capsid: From Structural Component to Key Factor for Host Nuclear Invasion.

Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages.

Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes.

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core.

Advanced Molecular Virology

Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells.

[Host nuclear pore factors: team players of HIV-1 nuclear translocation and integration].

Group for AIDS Research

SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal.

Chromatin organization at the nuclear pore favours HIV replication.

Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses

FlAsH-PALM: super-resolution pointillist imaging with FlAsH-tetracysteine labeling.

TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.

New insights in the role of nucleoporins: a bridge leading to concerted steps from HIV-1 nuclear entry until integration.

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration.

Superresolution imaging of HIV in infected cells with FlAsH-PALM.

TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core

HIV-derived vectors for therapy and vaccination against HIV.

Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection.

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha

Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase

Structural basis for functional tetramerization of lentiviral integrase

Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors

Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity

Transduction of human hematopoietic stem cells by lentiviral vectors pseudotyped with the RD114-TR chimeric envelope glycoprotein

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells