Ligne de temps

Ahmed Haouz
Responsable de Structure
30 Jan 2020
publication

Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein

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05 Dec 2019
publication

High-Throughput Crystallization Pipeline at the Crystallography Core Facility of the Institut Pasteur

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23 Apr 2019
publication

Double autoinhibition mechanism of signal transduction ATPases with numerous domains (STAND) with a tetratricopeptide repeat sensor

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16 Mar 2019
publication

The crystal structure of Rv2991 from Mycobacterium tuberculosis: An F binding protein with unknown function

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20 Feb 2019
publication

Orthobunyavirus spike architecture and recognition by neutralizing antibodies

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02 Feb 2019
publication

First-in-class allosteric inhibitors of bacterial IMPDHs

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27 Dec 2018
publication

Mercury(II) Binding to Metallothionein in Mytilus edulis revealed by High Energy-Resolution XANES Spectroscopy

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29 Oct 2018
publication

Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography

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26 Sep 2018
publication

An extracellular Leptospira interrogans leucine-rich repeat protein binds human E- and VE-cadherins

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01 Sep 2018
publication

An extracellular Leptospira interrogans leucine‐rich repeat protein binds human E‐ and VE‐cadherins

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13 Aug 2018
publication

Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes

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04 Aug 2018
publication

Conformational plasticity of the response regulator CpxR, a key player in Gammaproteobacteria virulence and drug-resistance

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15 Jul 2018
publication

Structural insights into the signalling mechanisms of two-component systems

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17 Feb 2018
publication

Structural snapshots along the reaction mechanism of the atypical poplar thioredoxin-like2.1

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18 Oct 2017
publication

Structure-function dissection of the Pseudorabies virus glycoprotein B fusion loops

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25 Jul 2017
publication

OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity

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23 May 2017
publication

Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope

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22 Feb 2017
publication

Bulgecin A: The Key to a Broad-Spectrum Inhibitor  That Targets Lytic Transglycosylases

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08 Jul 2016
publication

Insights into Brain Glycogen Metabolism: The Structure of Human Brain Glycogen Phosphorylase

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31 May 2016
publication

Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ

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18 May 2016
publication

Structural basis for haem piracy from host haemopexin by Haemophilus influenzae

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14 Nov 2015
publication

Structural insights into the loss of penicillinase and the gain of ceftazidimase activities by OXA-145 β-lactamase in Pseudomonas aeruginosa

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25 Aug 2015
publication

Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation

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02 Jul 2015
project

Chagas

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23 May 2015
publication

Structural characterization of a novel subfamily of leucine-rich repeat proteins from the human pathogen Leptospira interrogans

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17 Feb 2015
team

Cristallographie

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23 Jan 2015
publication

Insight into cofactor recognition in arylamine N-acetyltransferase enzymes: structure of Mesorhizobium loti arylamine N-acetyltransferase in complex with coenzyme A

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12 Jan 2015
publication

Recognition determinants of broadly neutralizing human antibodies against dengue viruses

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29 Nov 2014
publication

Glutathionyl-hydroquinone reductases from poplar are plastidial proteins that deglutathionylate both reduced and oxidized glutathionylated quinones

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29 Oct 2014
publication

Structural and functional characterization of an arylamine N-acetyltransferase from the pathogen Mycobacterium abscessus: differences from other mycobacterial isoforms and implications for selective inhibition

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15 Oct 2014
publication

Structural and functional features of Crl proteins and identification of conserved surface residues required for interaction with the RpoS/σS subunit of RNA polymerase

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27 Sep 2014
publication

Visualization of a substrate-induced productive conformation of the catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in SGNH esterase family members

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24 Sep 2014
publication

Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c

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10 Sep 2014
publication

A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase

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15 Aug 2014
publication

Structural and enzymatic insights into Lambda glutathione transferases from Populus trichocarpa, monomeric enzymes constituting an early divergent class specific to terrestrial plants

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01 Aug 2014
publication

6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: synthesis, structural studies and cytotoxic activities

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10 Apr 2014
publication

Structural basis of eukaryotic cell-cell fusion

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23 Dec 2013
publication

Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation

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11 Oct 2013
publication

Structural and functional characterization of an orphan ATP-binding cassette ATPase involved in manganese utilization and tolerance in Leptospira spp

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16 Jun 2013
publication

Structural and biochemical characterization of an active arylamine N-acetyltransferase possessing a non-canonical Cys-His-Glu catalytic triad

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24 Sep 2012
publication

In the absence of thioredoxins, what are the reductants for peroxiredoxins in Thermotoga maritima?

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11 Sep 2012
publication

Structural and functional characterization of VanG D-Ala:D-Ser ligase associated with vancomycin resistance in Enterococcus faecalis

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09 Jul 2012
publication

Crystal structure and functional mapping of human ASMT, the last enzyme of the melatonin synthesis pathway

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03 May 2012
publication

Conformational changes upon ligand binding in the essential class II fumarase Rv1098c from Mycobacterium tuberculosis

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26 Jan 2012
publication

Purification, crystallization and preliminary X-ray characterization of Bacillus cereus arylamine N-acetyltransferase 3 [(BACCR)NAT3]

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12 Oct 2011
publication

Peptides targeting the PDZ domain of PTPN4 are efficient inducers of glioblastoma cell death

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01 Jul 2011
publication

Insights into the Rrf2 repressor family–the structure of CymR, the global cysteine regulator of Bacillus subtilis

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01 Sep 2010
publication

Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance

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20 Aug 2010
publication

Molecular basis of vancomycin dependence in VanA-type Staphylococcus aureus VRSA-9

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15 Feb 2010
publication

Crystal structure of Mycobacterium tuberculosis LppA, a lipoprotein confined to pathogenic mycobacteria

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13 Nov 2009
publication

Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel

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23 Oct 2009
publication

DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding

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04 Oct 2009
publication

Recombinant plant gamma carbonic anhydrase homotrimers bind inorganic carbon

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23 Sep 2009
publication

Crystallization and preliminary X-ray analysis of a D-Ala:D-Ser ligase associated with VanG-type vancomycin resistance

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18 Sep 2009
publication

Structure of Mycobacterium tuberculosis Rv2714, a representative of a duplicated gene family in Actinobacteria

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04 Sep 2009
publication

Structural plasticity and catalysis regulation of a thermosensor histidine kinase

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16 Jan 2009
publication

Genome-wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis

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01 Jan 2008
publication

Crystal structure of a monoclonal antibody directed against an antigenic determinant common to Ogawa and Inaba serotypes of Vibrio cholerae O1

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20 Dec 2007
publication

Overproduction, purification, crystallization and preliminary X-ray analysis of the peroxiredoxin domain of a larger natural hybrid protein from Thermotoga maritima

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01 Oct 2007
publication

The crystal structure of Trypanosoma cruzi arginine kinase

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27 Jul 2007
publication

The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria

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02 Jul 2007
publication

Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives — a screening based on affinity for the UMP-CMP binding site

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15 Dec 2006
publication

The crystal structure of Rv0813c from Mycobacterium tuberculosis reveals a new family of fatty acid-binding protein-like proteins in bacteria

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22 Nov 2006
publication

Three dimensional structure and implications for the catalytic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei

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02 May 2006
publication

The crystal structure of Mycobacterium tuberculosis adenylate kinase in complex with two molecules of ADP and Mg2+ supports an associative mechanism for phosphoryl transfer

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25 Nov 2002
publication

Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism

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01 Jun 2002
publication

Database searching for thymidine and thymidylate kinase inhibitors using three-dimensional structure-based methods

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01 Jun 2002
publication

The crystal structure of the mouse apoptosis-inducing factor AIF

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