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X-ray diffraction
X-Ray Diffraction system is composed by : – A RIGAKU micromax 007 X-ray generator with standard rotating anode (wavelength 1.54 Å). – A system of multi-layer X-ray optics from OSMIC. – A mar345dtb […]
Generation of crystallization
Crystal optimization service To refine the conditions of crystallization, the robot Matrixmaker allows to generate solutions of crystallization on various kind of supports (tubes 50 ml, tubes 15 ml, tube Eppendorf 1.5 or 2 […]
Crystallization screening
Application process of crystallization at 18°C or 4°C In the platform we can setup high-throughput crystallization experiments (18°C or 4°C) with the vapour diffusion (sitting or hanging drop), the microbatch, and the cubic phase […]
Équipements
Serveur Bi-Processeur Intel Xeon • •
Serveur Bi-Processeur Intel Xeon baie de disques RAID Fibrenetix For datas analysis and storages
X Ray generator • •
X Ray generator Anode tournante (Rigaku MicroMax-O7) avec deux détecteurs à plaque image (MAR-345, MAR-300) Cryogenic systems (Cryojet Oxford Instruments, Oxford Cryosystem) for tridimensional structures of proteins
Robot Matrixmaker • •
Robot Matrixmaker Refinement of cristallization solutions Possible supports: Deep-Well, VDX(24 puits), tubes Eppendorf, 15ml, 50ml.
Robot Mosquito • •
Robot Mosquito Nanodrop cristallization Drop volumes from 100 to 1000nl Sitting drop Hanging drop possible
Membres
Ahmed Haouz
Responsable de Structure
Responsable
Anciens Membres
2000
2000
Name
Position
2015
2019
Sakina Kandouz
Undergraduate Student
2015
2019
Isabelle Miras
Technician
2015
2019
Jocelyne Fraysse
Administrative Staff
2015
2019
Frederick Saul
Retired scientist
Projets
Financements
Publications
Télécharger-
2020Evolution of abiotic cubane chemistries in a nucleic acid aptamer allows selective recognition of a malaria biomarker., Proc. Natl. Acad. Sci. U.S.A. 2020 Jul; (): .
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2020PLA2G1B is involved in CD4 anergy and CD4 lymphopenia in HIV-infected patients., J. Clin. Invest. 2020 Jun; 130(6): 2872-2887.
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2020Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum., Nat Commun 2020 Apr; 11(1): 1641.
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2020An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete, Elife 2020 Mar;9.
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2020Defective lytic transglycosylase disrupts cell morphogenesis by hindering cell wall de-O-acetylation in Neisseria meningitidis., Elife 2020 Feb; 9(): .
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2020Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein., Nat Commun 2020 01; 11(1): 596.
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2019High-Throughput Crystallization Pipeline at the Crystallography Core Facility of the Institut Pasteur, Molecules 2019 Dec;24(24).
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2019Directly Sequenced Genomes of Contemporary Strains of Syphilis Reveal Recombination-Driven Diversity in Genes Encoding Predicted Surface-Exposed Antigens, Front Microbiol 2019;10:1691.
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2019Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein, Sci Rep 2019 May;9(1):7438.
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2019Double autoinhibition mechanism of signal transduction ATPases with numerous domains (STAND) with a tetratricopeptide repeat sensor, Nucleic Acids Res. 2019 Apr;47(7):3795-3810.
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Contact
Phone : 01 40 61 39 30
Email : pf6@pasteur.fr
Adress :
25 Rue du Docteur Roux
75724, Paris France