Timeline

Frédéric Tangy
Head of Structure
02 Sep 2020
publication

RIG-I and PKR, but not stress granules, mediate the pro-inflammatory response to yellow fever virus.

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15 Jan 2019
publication

Uncovering Flavivirus Host Dependency Factors through a Genome-Wide Gain-of-Function Screen.

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01 Oct 2018
publication

DI-tector: defective interfering viral genomes’ detector for next-generation sequencing data.

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10 Jul 2018
publication

RIG-I Recognizes the 5′ Region of Dengue and Zika Virus Genomes.

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25 Sep 2017
event

10-Year Anniversary of the Institut Pasteur International Vaccinology Course

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21 Sep 2017
event

2017 INTERNATIONAL SOCIETY FOR VACCINES ANNUAL CONGRESS at INSTITUT PASTEUR

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14 Aug 2017
publication

Original chemical series of pyrimidine biosynthesis inhibitors that boost the antiviral interferon response

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31 May 2017
publication

Identification of a small molecule that primes the type I interferon response to cytosolic DNA

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24 Apr 2017
event

GPF Vaccinology day

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27 Feb 2017
event

VIROLOGY DEPARTMENT SEMINAR

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18 Oct 2016
publication

Oncolytic measles virus induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by human myeloid and plasmacytoid dendritic cells.

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24 Mar 2016
publication

Comparative analysis of viral RNA signatures on different RIG-I-like receptors

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12 Feb 2016
project

Group for AIDS Research

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10 Feb 2016
project

Emergency response to global threats of emerging and re-emerging pathogens

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08 Oct 2015
project

GPF Vaccinology Call 1: Open call for new ideas for cutting-edge science investigations in vaccinology.

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08 Oct 2015
project

GPF Vaccinology Call 2: Accelerating Preclinical Development of Vaccine Candidates

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07 Oct 2015
program_project

Major Federating Program Vaccinology

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01 Oct 2015
patent

A dengue virus chimeric polyepitope composed of fragments of non-structural proteins and its use in an immunogenic composition against dengue virus infection (E14305984.8)

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26 Sep 2015
project

Comics on vaccination

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04 Aug 2015
program_project

Defeat Dengue

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28 Jul 2015
project

Alkoxypyrazoles, inhibitors of dihydroorotate dehydrogenase (DHODH)

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04 Jul 2015
project

Bivalent vaccines derived from measles vaccine

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30 Jun 2015
publication

Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)

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11 May 2015
team

Innovation lab : vaccines

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02 Mar 2015
publication

Immunogenicity, safety, and tolerability of a recombinant measles-virus-based chikungunya vaccine: a randomised, double-blind, placebo-controlled, active-comparator, first-in-man trial

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06 Feb 2015
publication

[Stimulation of the antiviral innate immune response by pyrimidine biosynthesis inhibitors: a surprise of phenotypic screening]

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06 Jan 2015
publication

Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH)

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01 Jan 2015
publication

A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions

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23 Dec 2014
publication

Evidence for an intranasal immune response to human respiratory syncytial virus infection in cynomolgus macaques

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29 Aug 2014
publication

Use of SLAM and PVRL4 and identification of pro-HB-EGF as cell entry receptors for wild type phocine distemper virus

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05 May 2014
publication

High-throughput screening for broad-spectrum chemical inhibitors of RNA viruses

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29 Jan 2014
publication

Large-scale nucleotide optimization of simian immunodeficiency virus reduces its capacity to stimulate type I interferon in vitro

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28 Jan 2014
publication

Protection from SARS coronavirus conferred by live measles vaccine expressing the spike glycoprotein

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27 Jan 2014
publication

Whole Pichia pastoris yeast expressing measles virus nucleoprotein as a production and delivery system to multimerize Plasmodium antigens

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17 Oct 2013
publication

Yellow fever vaccine attenuation revealed: loss of diversity

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03 Oct 2013
publication

Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity

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30 Sep 2013
publication

Vaccines in development against West Nile virus

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07 Aug 2013
publication

The Golgi protein ACBD3, an interactor for poliovirus protein 3A, modulates poliovirus replication

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04 Jun 2013
publication

A recombinant measles vaccine expressing chikungunya virus-like particles is strongly immunogenic and protects mice from lethal challenge with chikungunya virus

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26 Apr 2013
publication

Species-specific impact of the autophagy machinery on Chikungunya virus infection

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01 Apr 2013
publication

Identification of RNA partners of viral proteins in infected cells

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28 Mar 2013
publication

Antitumor Virotherapy by Attenuated Measles Virus (MV)

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20 Mar 2013
publication

On dihydroorotate dehydrogenases and their inhibitors and uses

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14 Jan 2013
publication

The V protein of Tioman virus is incapable of blocking type I interferon signaling in human cells

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13 Dec 2012
publication

RelAp43, a member of the NF-κB family involved in innate immune response against Lyssavirus infection

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14 Sep 2012
publication

A phenotypic assay to identify Chikungunya virus inhibitors targeting the nonstructural protein nsP2

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13 Sep 2012
publication

Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A

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08 Aug 2012
publication

Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase

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02 May 2012
publication

Measles vaccine expressing the secreted form of West Nile virus envelope glycoprotein induces protective immunity in squirrel monkeys, a new model of West Nile virus infection

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02 May 2012
publication

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes

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18 Apr 2012
publication

The biased nucleotide composition of HIV-1 triggers type I interferon response and correlates with subtype D increased pathogenicity

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18 Jan 2012
publication

Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component

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12 Sep 2011
publication

Proteomic analysis of virus-host interactions in an infectious context using recombinant viruses

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03 Sep 2011
publication

A chimeric measles virus with a lentiviral envelope replicates exclusively in CD4+/CCR5+ cells

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20 Jul 2011
publication

The interaction of flavivirus M protein with light chain Tctex-1 of human dynein plays a role in late stages of virus replication

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09 Sep 2010
publication

Virus-host protein interactions in RNA viruses

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03 Aug 2010
publication

Pediatric measles vaccine expressing a dengue tetravalent antigen elicits neutralizing antibodies against all four dengue viruses

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14 Apr 2010
publication

Enhanced gene silencing in cells cured of persistent virus infection by RNA interference

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11 Nov 2009
publication

Structure of the nucleoprotein binding domain of Mokola virus phosphoprotein

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27 Oct 2009
publication

Study of human RIG-I polymorphisms identifies two variants with an opposite impact on the antiviral immune response

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18 Sep 2009
publication

Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor

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17 Jul 2009
publication

NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein

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22 Jun 2009
publication

Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS

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05 Apr 2009
publication

Live attenuated measles vaccine expressing HIV-1 Gag virus like particles covered with gp160DeltaV1V2 is strongly immunogenic

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12 Nov 2008
publication

Inhibition of IFN-alpha/beta signaling by two discrete peptides within measles virus V protein that specifically bind STAT1 and STAT2

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17 Jun 2008
publication

Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein

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30 May 2008
publication

Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs

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12 Dec 2007
publication

Pediatric measles vaccine expressing a dengue antigen induces durable serotype-specific neutralizing antibodies to dengue virus

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14 Sep 2007
publication

Recombinant vector derived from live attenuated measles virus: potential for flavivirus vaccines

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07 Aug 2007
publication

Measles virus V protein blocks Jak1-mediated phosphorylation of STAT1 to escape IFN-alpha/beta signaling

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22 Aug 2005
publication

A recombinant live attenuated measles vaccine vector primes effective HLA-A0201-restricted cytotoxic T lymphocytes and broadly neutralizing antibodies against HIV-1 conserved epitopes

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01 May 2005
publication

A paediatric vaccination vector based on live attenuated measles vaccine

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10 Apr 2005
publication

The antimicrobial peptide dermaseptin S4 inhibits HIV-1 infectivity in vitro

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01 Jan 2005
publication

Live attenuated measles vaccine as a potential multivalent pediatric vaccination vector

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15 Dec 2004
publication

A chimeric human T cell leukemia virus type I bearing a deltaR Moloney-murine leukemia virus envelope infects mice persistently and induces humoral and cellular immune responses

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10 Dec 2004
publication

Live measles vaccine expressing the secreted form of the West Nile virus envelope glycoprotein protects against West Nile virus encephalitis

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01 Jan 2004
publication

A single injection of recombinant measles virus vaccines expressing human immunodeficiency virus (HIV) type 1 clade B envelope glycoproteins induces neutralizing antibodies and cellular immune responses to HIV

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01 Aug 2002
publication

A chimeric human T-cell lymphotropic virus type 1 with the envelope glycoprotein of Moloney murine leukemia virus is infectious for murine cells

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