Ligne de temps
Frédéric Tangy
Chercheur(euse) Permanent(e)
09 mars 2024
publication
Comparative analysis of rabies pathogenic and vaccine strains detection by RIG-I-like receptors.
Lire plus05 févr. 2024
19 déc. 2023
publication
NDP52 mediates an antiviral response to hepatitis B virus infection through Rab9-dependent lysosomal degradation pathway.
Lire plus30 sept. 2023
11 mars 2023
publication
Rapid protection induced by a single-shot Lassa vaccine in male cynomolgus monkeys
Lire plus15 juil. 2022
publication
Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1
Lire plus22 déc. 2021
publication
sgDI-tector: defective interfering viral genome bioinformatics for detection of coronavirus subgenomic RNAs
Lire plus14 déc. 2021
01 nov. 2021
publication
A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters
Lire plus09 sept. 2021
01 sept. 2021
publication
Discovery of genes that modulate flavivirus replication in an interferon-dependent manner
Lire plus09 juin 2021
publication
A single-shot Lassa vaccine induces long-term immunity and protects cynomolgus monkeys against heterologous strains.
Lire plus27 janv. 2021
publication
Proteomic Analysis Uncovers Measles Virus Protein C Interaction With p65–iASPP Protein Complex
Lire plus27 oct. 2020
publication
Retinoic Acid Inducible Gene I and Protein Kinase R, but Not Stress Granules, Mediate the Proinflammatory Response to Yellow Fever Virus
Lire plus15 janv. 2019
publication
Uncovering Flavivirus Host Dependency Factors through a Genome-Wide Gain-of-Function Screen.
Lire plus01 oct. 2018
publication
DI-tector: defective interfering viral genomes’ detector for next-generation sequencing data.
Lire plus10 juil. 2018
25 sept. 2017
21 sept. 2017
14 août 2017
publication
Original chemical series of pyrimidine biosynthesis inhibitors that boost the antiviral interferon response
Lire plus24 avr. 2017
27 févr. 2017
18 oct. 2016
publication
Oncolytic measles virus induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by human myeloid and plasmacytoid dendritic cells.
Lire plus24 mars 2016
publication
Comparative analysis of viral RNA signatures on different RIG-I-like receptors
Lire plus12 févr. 2016
08 oct. 2015
project
GPF Vaccinology Call 1: Open call for new ideas for cutting-edge science investigations in vaccinology.
Lire plus08 oct. 2015
project
GPF Vaccinology Call 2: Accelerating Preclinical Development of Vaccine Candidates
Lire plus07 oct. 2015
01 oct. 2015
patent
A dengue virus chimeric polyepitope composed of fragments of non-structural proteins and its use in an immunogenic composition against dengue virus infection (E14305984.8)
Lire plus26 sept. 2015
28 juil. 2015
04 juil. 2015
30 juin 2015
publication
Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)
Lire plus02 mars 2015
publication
Immunogenicity, safety, and tolerability of a recombinant measles-virus-based chikungunya vaccine: a randomised, double-blind, placebo-controlled, active-comparator, first-in-man trial
Lire plus06 janv. 2015
publication
Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH)
Lire plus01 janv. 2015
publication
A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions
Lire plus23 déc. 2014
publication
Evidence for an intranasal immune response to human respiratory syncytial virus infection in cynomolgus macaques
Lire plus29 août 2014
publication
Use of SLAM and PVRL4 and identification of pro-HB-EGF as cell entry receptors for wild type phocine distemper virus
Lire plus05 mai 2014
publication
High-throughput screening for broad-spectrum chemical inhibitors of RNA viruses
Lire plus28 janv. 2014
publication
Protection from SARS coronavirus conferred by live measles vaccine expressing the spike glycoprotein
Lire plus27 janv. 2014
publication
Whole Pichia pastoris yeast expressing measles virus nucleoprotein as a production and delivery system to multimerize Plasmodium antigens.
Lire plus17 oct. 2013
03 oct. 2013
publication
Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity
Lire plus30 sept. 2013
07 août 2013
publication
The Golgi protein ACBD3, an interactor for poliovirus protein 3A, modulates poliovirus replication
Lire plus04 juin 2013
publication
A recombinant measles vaccine expressing chikungunya virus-like particles is strongly immunogenic and protects mice from lethal challenge with chikungunya virus
Lire plus01 juin 2013
publication
Species-specific impact of the autophagy machinery on Chikungunya virus infection.
Lire plus01 avr. 2013
28 mars 2013
20 mars 2013
14 janv. 2013
publication
The V protein of Tioman virus is incapable of blocking type I interferon signaling in human cells
Lire plus13 déc. 2012
publication
RelAp43, a member of the NF-κB family involved in innate immune response against Lyssavirus infection
Lire plus14 sept. 2012
publication
A phenotypic assay to identify Chikungunya virus inhibitors targeting the nonstructural protein nsP2
Lire plus13 sept. 2012
08 août 2012
publication
Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase
Lire plus02 mai 2012
publication
Measles vaccine expressing the secreted form of West Nile virus envelope glycoprotein induces protective immunity in squirrel monkeys, a new model of West Nile virus infection
Lire plus02 mai 2012
publication
A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes
Lire plus01 mars 2012
publication
Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component.
Lire plus12 sept. 2011
publication
Proteomic analysis of virus-host interactions in an infectious context using recombinant viruses
Lire plus03 sept. 2011
publication
A chimeric measles virus with a lentiviral envelope replicates exclusively in CD4+/CCR5+ cells
Lire plus20 juil. 2011
publication
The interaction of flavivirus M protein with light chain Tctex-1 of human dynein plays a role in late stages of virus replication
Lire plus09 sept. 2010
03 août 2010
publication
Pediatric measles vaccine expressing a dengue tetravalent antigen elicits neutralizing antibodies against all four dengue viruses
Lire plus14 avr. 2010
publication
Enhanced gene silencing in cells cured of persistent virus infection by RNA interference
Lire plus11 nov. 2009
27 oct. 2009
publication
Study of human RIG-I polymorphisms identifies two variants with an opposite impact on the antiviral immune response
Lire plus18 sept. 2009
publication
Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor
Lire plus17 juil. 2009
publication
NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein
Lire plus22 juin 2009
05 avr. 2009
publication
Live attenuated measles vaccine expressing HIV-1 Gag virus like particles covered with gp160DeltaV1V2 is strongly immunogenic
Lire plus12 nov. 2008
publication
Inhibition of IFN-alpha/beta signaling by two discrete peptides within measles virus V protein that specifically bind STAT1 and STAT2
Lire plus17 juin 2008
publication
Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein
Lire plus30 mai 2008
publication
Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs
Lire plus12 déc. 2007
publication
Pediatric measles vaccine expressing a dengue antigen induces durable serotype-specific neutralizing antibodies to dengue virus
Lire plus14 sept. 2007
publication
Recombinant vector derived from live attenuated measles virus: potential for flavivirus vaccines
Lire plus07 août 2007
publication
Measles virus V protein blocks Jak1-mediated phosphorylation of STAT1 to escape IFN-alpha/beta signaling
Lire plus22 août 2005
publication
A recombinant live attenuated measles vaccine vector primes effective HLA-A0201-restricted cytotoxic T lymphocytes and broadly neutralizing antibodies against HIV-1 conserved epitopes
Lire plus01 mai 2005
10 avr. 2005
01 janv. 2005
publication
Live attenuated measles vaccine as a potential multivalent pediatric vaccination vector
Lire plus15 déc. 2004
publication
A chimeric human T cell leukemia virus type I bearing a deltaR Moloney-murine leukemia virus envelope infects mice persistently and induces humoral and cellular immune responses.
Lire plus10 déc. 2004
publication
Live measles vaccine expressing the secreted form of the West Nile virus envelope glycoprotein protects against West Nile virus encephalitis
Lire plus01 janv. 2004
publication
A single injection of recombinant measles virus vaccines expressing human immunodeficiency virus (HIV) type 1 clade B envelope glycoproteins induces neutralizing antibodies and cellular immune responses to HIV
Lire plus01 août 2002
publication