Timeline

Asier Sáez-Cirión
Group Leader
02 Aug 2019
publication

The proportion of CD57+ cells among effector CD8+ T cells is lower HIV controllers compared to ART treated patients

Read more
10 May 2019
event

Groupe de Réflexion SIDA (GRS) meeting: “Mechanisms of HIV antigen presentation”

Read more
06 May 2019
publication

The Yellow Brick Road towards HIV Eradication

Read more
01 May 2019
publication

HIV Controllers Have Low Inflammation Associated with a Strong HIV-Specific Immune Response in Blood

Read more
08 Apr 2019
event

Groupe de Reflexion SIDA (GRS) seminar: “Determinants of HIV-1 broadly neutralizing antibody induction”

Read more
04 Mar 2019
event

Groupe de Réflexion SIDA (GRS) meeting: “Mechanisms of restriction of viral entry”

Read more
26 Feb 2019
publication

Safety of CD34 Hematopoietic Stem Cells and CD4 T Lymphocytes Transduced with LVsh5/C46 in HIV-1 Infected Patients with High-Risk Lymphoma

Read more
31 Jan 2019
project

Archive of the Group for AIDS Research

Read more
01 Jan 2019
publication

Dynamics in HIV-DNA levels over time in HIV controllers

Read more
19 Dec 2018
publication

Cellular Metabolism Is a Major Determinant of HIV-1 Reservoir Seeding in CD4 T Cells and Offers an Opportunity to Tackle Infection

Read more
21 Nov 2018
event

Groupe de Reflexion SIDA (GRS) seminar: “Tissue-like 3D environment shape modes of HIV-spread”

Read more
18 Sep 2018
event

Groupe de Réflexion SIDA (GRS) seminar: “Defining Correlates of Immunology using Systems Serology”

Read more
27 Aug 2018
news

MOOC on HIV Science (registration free)

Read more
22 May 2018
event

Groupe de Réflexion SIDA (GRS) meeting: “Humanized mice models for HIV studies”

Read more
27 Feb 2018
event

GRS (Groupe de Réflexion SIDA) meeting: “Immune reconstitution in HIV infection”

Read more
02 Feb 2018
event

Groupe de Réflexion SIDA (GRS) meeting: “Metabolism and HIV”

Read more
12 Jan 2018
publication

Immune Responses to Retroviruses

Read more
01 Jan 2018
publication

Cellular Determinants of HIV Persistence on Antiretroviral Therapy

Read more
31 Oct 2017
event

Groupe de Réflexion SIDA (GRS) meeting: “HIV vaccination strategies”

Read more
11 Oct 2017
publication

Saporin-conjugated tetramers identify efficacious anti-HIV CD8+ T-cell specificities

Read more
20 Sep 2017
publication

p21 Restricts HIV-1 in Monocyte-Derived Dendritic Cells through the Reduction of Deoxynucleoside Triphosphate Biosynthesis and Regulation of SAMHD1 Antiviral Activity

Read more
06 Sep 2017
publication

HLA-B*14:02-RESTRICTED ENV-SPECIFIC CD8+ T-CELL ACTIVITY HAS HIGHLY POTENT ANTIVIRAL EFFICACY ASSOCIATED WITH IMMUNE CONTROL OF HIV INFECTION

Read more
28 Jun 2017
publication

Clinical and public health implications of acute and early HIV detection and treatment: a scoping review

Read more
06 Apr 2017
event

GRS (Groupe de Reflexion SIDA) meeting: “Residual risk of HIV sexual transmission”

Read more
03 Apr 2017
publication

A Subset of Extreme Human Immunodeficiency Virus (HIV) Controllers Is Characterized by a Small HIV Blood Reservoir and a Weak T-Cell Activation Level

Read more
28 Feb 2017
publication

Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents

Read more
24 Sep 2016
publication

Polyfunctional HIV-specific T cells in Post-Treatment Controllers

Read more
26 Aug 2016
publication

Preservation of Lymphopoietic Potential and Virus Suppressive Capacity by CD8+ T Cells in HIV-2-Infected Controllers

Read more
19 Aug 2016
publication

Strong Ifitm1 Expression In Cd4 T Cells In Hiv Controllers Is Correlated With Immune Activation

Read more
10 Aug 2016
publication

Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset

Read more
09 Aug 2016
publication

Dendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles

Read more
11 Jul 2016
publication

International AIDS Society global scientific strategy: towards an HIV cure 2016

Read more
27 Apr 2016
publication

Long-term Spontaneous control of HIV-1 relates to low frequency of infected cells and inefficient viral reactivation

Read more
12 Feb 2016
project

Group for AIDS Research

Read more
09 Dec 2015
publication

HIV-1 virological remission lasting more than 12 years after interruption of early antiretroviral therapy in a perinatally infected teenager enrolled in the French ANRS EPF-CO10 paediatric cohort: a case report

Read more
10 Sep 2015
project

ICISTEM-International Collaboration to guide and investigate the potential for HIV cure by Stem Cell Transplantation

Read more
09 Sep 2015
project

Etude ANRS-EP59-CLEAC (Comparison of Late versus Early Antiretroviral therapy in HIV-infected Children) : Etude physiopathologique comparant l’impact de l’instauration précoce (avant 6 mois) ou tardive (après 2 ans) du traitement antirétroviral sur l’évolution immuno-virologique des enfants infectés par le VIH-1 en période périnatale)

Read more
03 Sep 2015
project

Natural Control of HIV-1 Infection

Read more
03 Sep 2015
project

Role of CD8 T cells responses in the control of HIV-2 infection-ANRS Immunovir2

Read more
16 Jul 2015
team

Group: Viral Reservoirs and Control

Read more
06 Jul 2015
publication

Immunologic and Virologic Progression in HIV Controllers: The Role of Viral “Blips” and Immune Activation in the ANRS CO21 CODEX Study

Read more
11 May 2015
team

HIV, Inflammation and Persistence

Read more
21 Apr 2015
publication

Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission

Read more
18 Feb 2015
publication

Intensive five-drug antiretroviral therapy regimen versus standard triple-drug therapy during primary HIV-1 infection (OPTIPRIM-ANRS 147): a randomised, open-label, phase 3 trial

Read more
14 Jan 2015
publication

Long-term control of simian immunodeficiency virus (SIV) in cynomolgus macaques not associated with efficient SIV-specific CD8+ T-cell responses

Read more
12 Jan 2015
publication

Immediate T-Helper 17 Polarization Upon Triggering CD11b/c on HIV-Exposed Dendritic Cells

Read more
01 Jan 2015
publication

Posttreatment controllers: what do they tell us?

Read more
06 Aug 2014
publication

High eomesodermin expression among CD57+ CD8+ T cells identifies a CD8+ T cell subset associated with viral control during chronic human immunodeficiency virus infection

Read more
07 Jul 2014
publication

Potential role for HIV-specific CD38-/HLA-DR+ CD8+ T cells in viral suppression and cytotoxicity in HIV controllers

Read more
12 May 2014
publication

Immune responses during spontaneous control of HIV and AIDS: what is the hope for a cure?

Read more
01 Apr 2014
publication

Reply to Pauls et al.: p21 is a master regulator of HIV replication in macrophages through dNTP synthesis block

Read more
11 Mar 2014
publication

HIV cure research: advances and prospects

Read more
20 Feb 2014
publication

What is the significance of posttreatment control of HIV infection vis-à-vis functional cure?

Read more
20 Feb 2014
publication

The link between CD8⁺ T-cell antigen-sensitivity and HIV-suppressive capacity depends on HLA restriction, target epitope and viral isolate

Read more
20 Feb 2014
publication

Elevated IP10 levels are associated with immune activation and low CD4⁺ T-cell counts in HIV controller patients

Read more
17 Jan 2014
publication

Blunted response to combination antiretroviral therapy in HIV elite controllers: an international HIV controller collaboration

Read more
16 Oct 2013
publication

Both HLA-B*57 and plasma HIV RNA levels contribute to the HIV-specific CD8+ T cell response in HIV controllers

Read more
30 Sep 2013
publication

p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway

Read more
23 Sep 2013
publication

High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers

Read more
01 Jul 2013
publication

HIV controllers: a genetically determined or inducible phenotype?

Read more
01 May 2013
publication

Will it be possible to live without antiretroviral therapy?

Read more
29 Mar 2013
publication

CD8 T-cells from most HIV-infected patients lack ex vivo HIV-suppressive capacity during acute and early infection

Read more
25 Mar 2013
publication

Immunovirologic control 24 months after interruption of antiretroviral therapy initiated close to HIV seroconversion

Read more
14 Mar 2013
publication

Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study

Read more
01 Jan 2013
publication

NKG2D expression on HIV-specific CD8+ T cells is reduced in viremic HIV-1-infected patients but maintained in HIV controllers

Read more
13 Oct 2012
publication

Immunodominance of HLA-B27-restricted HIV KK10-specific CD8(+) T-cells is not related to naïve precursor frequency

Read more
11 Oct 2012
publication

Antibodies attenuate the capacity of dendritic cells to stimulate HIV-specific cytotoxic T lymphocytes

Read more
06 Mar 2012
publication

Kidney transplantation in an elite HIV controller: limited impact of immunosuppressive therapy on viro-immunological status

Read more
03 Jun 2011
publication

Restriction of HIV-1 replication in macrophages and CD4+ T cells from HIV controllers

Read more
21 Apr 2011
publication

CD4 dynamics over a 15 year-period among HIV controllers enrolled in the ANRS French observatory

Read more
01 Nov 2010
publication

Natural resistance to HIV infection: lessons learned from HIV‐exposed uninfected individuals

Read more
13 May 2010
publication

Ex vivo T cell-based HIV suppression assay to evaluate HIV-specific CD8+ T-cell responses

Read more
15 Jun 2009
publication

Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses

Read more
23 Apr 2009
publication

Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity

Read more
04 Jan 2008
publication

The characteristic CD8+ T cell response in HIV controllers: an objective to achieve?

Read more
03 Jan 2008
publication

Interfacial pre-transmembrane domains in viral proteins promoting membrane fusion and fission

Read more
05 Nov 2007
publication

HIV controllers: how do they tame the virus?

Read more
16 May 2007
publication

Ku80 participates in the targeting of retroviral transgenes to the chromatin of CHO cells

Read more
11 May 2007
publication

Replication-competent HIV strains infect HIV controllers despite undetectable viremia (ANRS EP36 study)

Read more
11 Apr 2007
publication

HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype

Read more
08 Nov 2006
publication

Persistent resistance to HIV-1 infection in CD4 T cells from exposed uninfected Vietnamese individuals is mediated by entry and post-entry blocks

Read more
01 Nov 2006
publication

The engagement of activating FcgammaRs inhibits primate lentivirus replication in human macrophages

Read more
01 Jun 2006
publication

Quantitative real-time analysis of HIV-1 gene expression dynamics in single living primary cells

Read more
06 Apr 2005
publication

First Dominique Dormont International Conference on “Host-pathogen interactions in chronic infections – viral and host determinants of HCV, HCMV, and HIV infections”

Read more
01 Dec 2003
publication

Structural and functional roles of HIV-1 gp41 pretransmembrane sequence segmentation

Read more
01 Nov 2003
publication

The hydrophobic internal region of bovine prion protein shares structural and functional properties with HIV type 1 fusion peptide

Read more
01 Jan 2003
publication

Pre-transmembrane sequence of Ebola glycoprotein. Interfacial hydrophobicity distribution and interaction with membranes

Read more
19 Aug 2002
publication

Conformational transitions of membrane-bound HIV-1 fusion peptide

Read more
02 Apr 2002
publication

Sphingomyelin and cholesterol promote HIV-1 gp41 pretransmembrane sequence surface aggregation and membrane restructuring

Read more
31 Aug 2000
publication

Sphingolipids (Galactosylceramide and Sulfatide) in Lamellar−Hexagonal Phospholipid Phase Transitions and in Membrane Fusion

Read more
14 Jul 2000
publication

The pre-transmembrane region of the human immunodeficiency virus type-1 glycoprotein: a novel fusogenic sequence

Read more
01 Jan 2000
publication

Equilibrium and Kinetic Studies of the Solubilization of Phospholipid−Cholesterol Bilayers by C12E8. The Influence of the Lipid Phase Structure

Read more