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© Charles Dauguet
Virus VIH-2, second virus du sida isolé en 1985 par l'équipe du Pr. Montagnier de l'Institut Pasteur.
Publication : The lancet. HIV

HIV controllers: to treat or not to treat? Is that the right question?

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in The lancet. HIV - 14 Oct 2019

Noël N, Saez-Cirion A, Avettand-Fenoël V, Boufassa F, Lambotte O

Link to Pubmed [PMID] – 31624011

Lancet HIV 2019 Oct;

The term HIV controller refers to the small proportion of individuals infected with HIV who can spontaneously control viraemia to maintain very low viral loads. One major unresolved question is whether HIV controllers should receive antiretroviral therapy, given that international guidelines recommend treatment for all individuals who are infected with HIV. Differences in the definitions of a controller (in terms of the viral-load cutoff and the duration of viral control) and contrasting reports on CD4 T-cell decline, chronic immune activation, the cardiovascular risk, and loss of viral control in controllers have prevented the development of a consensus view.

https://www.ncbi.nlm.nih.gov/pubmed/31624011