Timeline

Hélène Strick-Marchand
Group Leader
25 Aug 2023
publication

A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR+ cells during antibody-mediated immune responses.

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01 Nov 2021
publication

A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters

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09 Sep 2021
course

MOOC Viruses and Human Cancers

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06 Apr 2021
project

Modeling SARS-CoV-2 infection and immune responses in humanized mouse models

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06 Mar 2021
publication

Animal Models for Hepatitis B: Does the Supply Meet the Demand?

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24 Jun 2020
publication

Potent human broadly neutralizing antibodies to hepatitis B virus from natural controllers.

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06 Mar 2020
project

Immune profiling to guide host-directed interventions to cure HBV

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27 Feb 2020
publication

In-vitro and in-vivo models for hepatitis B cure research

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27 Jan 2020
publication

Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses In Vitro and in Humanized Mice.

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01 Jun 2019
publication

Accelerated thymopoiesis and improved T-cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice.

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01 Aug 2018
publication

A human immune system mouse model with robust lymph node development.

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17 Apr 2018
event

“Disruptive Discoveries for HIV, HCV and HBV Infections” by Raymond Schinazi – Virology & Immunology departments joint seminar

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01 Mar 2018
publication

Who Defends the Stem Cell’s Citadel?

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30 Dec 2017
news

Yin and Yang of IL-2 Therapy

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24 Nov 2017
publication

Regulatory T cells control toxicity in a humanized model of IL-2 therapy

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31 Aug 2017
publication

Modeling hepatitis virus infections and treatment strategies in humanized mice

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26 Apr 2017
event

Raymond Schinazi seminar

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06 Apr 2017
publication

A functional DC cross talk promotes human ILC homeostasis in humanized mice.

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19 Mar 2017
news

‘ILC-poiesis’: A new model of human ILC differentiation

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09 Mar 2017
publication

Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.

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01 Mar 2016
publication

A novel Flt3-deficient HIS mouse model with selective enhancement of human DC development.

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18 Feb 2016
publication

Progressive developmental restriction, acquisition of left-right identity and cell growth behavior during lobe formation in mouse liver development

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21 Oct 2015
project

Pathogen co-infection : HIV, TB, Malaria and HCV

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05 Sep 2015
project

Humanized mouse models for studying viral hepatitis

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16 Jul 2015
team

Group: Humanized mice for infectious disease modeling

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11 May 2015
team

Innate Immunity

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10 Feb 2015
publication

Towards an HBV cure: state-of-the-art and unresolved questions–report of the ANRS workshop on HBV cure

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01 Jan 2014
publication

Animal models to test hiPS-derived hepatocytes in the context of inherited metabolic liver diseases.

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01 Oct 2012
publication

Ectopic expression of murine CD47 minimizes macrophage rejection of human hepatocyte xenografts in immunodeficient mice

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02 Jun 2012
publication

Production of hepatitis B defective particles is dependent on liver status

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12 Oct 2011
publication

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

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30 Aug 2011
publication

Autonomous and extrinsic regulation of thymopoiesis in human immune system (HIS) mice

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25 Jul 2011
publication

Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo

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28 Mar 2011
publication

IL-15 transpresentation promotes both human T-cell reconstitution and T-cell-dependent antibody responses in vivo

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01 May 2010
publication

Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development

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23 Jul 2009
publication

Humanized mice for modeling human infectious disease: challenges, progress, and outlook

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01 Dec 2008
publication

Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer

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15 Aug 2008
publication

Lymphocytes support oval cell-dependent liver regeneration

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05 Jun 2008
publication

Morphogenetic competence of HNF4 alpha-deficient mouse hepatic cells

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12 Sep 2007
publication

Gamma c cytokines condition the progressive differentiation of CD4+ T cells

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19 Jul 2007
publication

Transcriptional profiling of bipotential embryonic liver cells to identify liver progenitor cell surface markers

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01 Sep 2006
publication

Plasticity of hepatic cell differentiation: bipotential adult mouse liver clonal cell lines competent to differentiate in vitro and in vivo

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01 Dec 2004
publication

Transcription factor HNF-6/OC-1 inhibits the stimulation of the HNF-3alpha/Foxa1 gene by TGF-beta in mouse liver

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20 May 2004
publication

Bipotential mouse embryonic liver stem cell lines contribute to liver regeneration and differentiate as bile ducts and hepatocytes

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01 Nov 2003
publication

Isolation and characterization of mouse hepatic stem cells in vitro

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01 Jan 2003
publication

Embryonic liver cells and permanent lines as models for hepatocyte and bile duct cell differentiation

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01 Oct 2002
publication

Inducible differentiation and morphogenesis of bipotential liver cell lines from wild-type mouse embryos

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