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© Research
Publication : Seminars in liver disease

Isolation and characterization of mouse hepatic stem cells in vitro

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Seminars in liver disease - 01 Nov 2003

Weiss MC, Strick-Marchand H

Link to Pubmed [PMID] – 14722809

Semin. Liver Dis. 2003 Nov;23(4):313-24

This article covers mouse cell lines showing the properties of hepatoblasts or oval cells and describes hepatocyte differentiation obtained from embryonic stem (ES) cells and mesenchymal adult progenitor cells. It considers the methods used for cultivation and differentiation of the cells, as well as the strengths and weaknesses of the different systems and perspectives for future research. Emphasis is given to hepatoblast cell lines because this is the material for which bipotentiality has been most clearly demonstrated and for which proliferation and differentiation conditions have been worked out.

http://www.ncbi.nlm.nih.gov/pubmed/14722809