Timeline

Nadia Izadi-Pruneyre
Group Leader
09 Jul 2019
news

Post-doc available

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23 May 2019
publication

Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches

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09 Apr 2019
publication

Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus.

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26 Jan 2019
event

11th Conference “NMR: a tool for Biology”, 28-30 Jan 2019

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24 Jan 2019
patent

Docking method based on saturation transfer difference NMR data, and means for its implementation WO 2019/011987

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18 Dec 2018
publication

Target engagement and binding mode of an anti-tuberculosis drug to its bacterial target deciphered in whole living cells by NMR.

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06 Apr 2018
event

Seminar of the Department of Structural Biology and Chemistry

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05 Apr 2018
event

Inhibiting Chromatin Assembly by Targeting Histone Chaperones

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09 Mar 2018
project

Protein synthesis machinery of Trypanosomatid as a therapeutic target

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27 Dec 2017
event

Dr. OCHSENBEIN Françoise – “Inhibiting Chromatin Assembly by Targeting Histone Chaperones” (CANCELLED)

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28 Nov 2017
project

ViBrANT (Viral and Bacterial Adhesin Network Training)

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09 Oct 2017
publication

Structure of the calcium-dependent type 2 secretion pseudopilus

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21 May 2017
publication

1H, 15N and 13C resonance assignments and secondary structure of PulG, the major pseudopilin from Klebsiella oxytoca type 2 secretion system.

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27 May 2016
publication

Structural basis of the signaling through a bacterial membrane receptor HasR deciphered by an integrative approach.

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09 Sep 2015
tool

Nuclear Magnetic Resonance spectrometers

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31 Aug 2015
project

Binding mode of promising antituberculosis clinical compounds to their bacterial target

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28 Aug 2015
team

Structural Biology of Membrane Complexes

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22 Jul 2015
project

FiberSpace

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07 Jul 2015
project

Bacterial Transmembrane Signaling

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01 Jun 2015
publication

A tribute to Cécile Wandersman

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11 May 2015
team

Structural Bioinformatics

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11 Apr 2014
publication

Interaction of a partially disordered antisigma factor with its partner, the signaling domain of the TonB-dependent transporter HasR

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19 Mar 2013
publication

The structure of HasB reveals a new class of TonB protein fold

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15 Dec 2012
publication

¹H, ¹⁵N and ¹³C resonance assignments of PpdD, a type IV pilin from enterohemorrhagic Escherichia coli

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14 Jun 2012
publication

Role of the iron axial ligands of heme carrier HasA in heme uptake and release

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14 Mar 2012
publication

(1)H, (13)C and (15)N resonance assignments of the periplasmic signalling domain of HasR, a TonB-dependent outer membrane heme transporter

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11 Feb 2009
publication

Mapping the interaction between the hemophore HasA and its outer membrane receptor HasR using CRINEPT-TROSY NMR spectroscopy

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14 Jan 2009
publication

Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex

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28 Mar 2008
publication

Modulation by substrates of the interaction between the HasR outer membrane receptor and its specific TonB-like protein, HasB

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19 Jan 2008
publication

Novel heme ligand displacement by CO in the soluble hemophore HasA and its proximal ligand mutants: implications for heme uptake and release

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27 Dec 2007
publication

Deciphering the structural role of histidine 83 for heme binding in hemophore HasA

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04 Dec 2007
publication

Comparative analysis of structural and dynamic properties of the loaded and unloaded hemophore HasA: functional implications

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03 Nov 2007
publication

(1)H, (13)C and (15)N resonance assignments of the C-terminal domain of HasB, a specific TonB like protein, from Serratia marcescens

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04 May 2007
publication

Mutagenesis and molecular modeling reveal three key extracellular loops of the membrane receptor HasR that are involved in hemophore HasA binding

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25 Oct 2006
publication

The crystal structure of the secreted dimeric form of the hemophore HasA reveals a domain swapping with an exchanged heme ligand

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14 Jun 2006
publication

The heme transfer from the soluble HasA hemophore to its membrane-bound receptor HasR is driven by protein-protein interaction from a high to a lower affinity binding site

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01 Oct 2003
publication

Role of the tyrosine corner motif in the stability of neocarzinostatin

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01 Oct 2003
publication

Ligand delivery by haem carrier proteins: the binding of Serratia marcescens haemophore to its outer membrane receptor is mediated by two distinct peptide regions

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16 Sep 2003
publication

Thermodynamics of heme binding to the HasA(SM) hemophore: effect of mutations at three key residues for heme uptake

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01 Nov 2001
publication

Key interactions in the immunoglobulin-like structure of apo-neocarzinostatin: evidence from nuclear magnetic resonance relaxation data and molecular dynamics simulations

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01 Nov 2000
publication

Functional aspects of the heme bound hemophore HasA by structural analysis of various crystal forms

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01 Mar 2000
publication

Simple and accurate determination of global tau(R) in proteins using (13)C or (15)N relaxation data

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01 Jan 2000
publication

Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease

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01 Jun 1999
publication

Backbone NMR assignment and secondary structure of the 19 kDa hemophore HasA

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01 Jun 1999
publication

The crystal structure of HasA, a hemophore secreted by Serratia marcescens

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01 Apr 1999
publication

NMR studies of the C-terminal secretion signal of the haem-binding protein, HasA

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10 Jun 1997
publication

Purification and characterization of an extracellular heme-binding protein, HasA, involved in heme iron acquisition

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