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© Research
Publication : Biomolecular NMR assignments

(1)H, (13)C and (15)N resonance assignments of the periplasmic signalling domain of HasR, a TonB-dependent outer membrane heme transporter

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Biomolecular NMR assignments - 14 Mar 2012

Malki I, Cardoso de Amorim G, Simenel C, Prochnicka-Chalufour A, Delepierre M, Izadi-Pruneyre N

Link to Pubmed [PMID] – 22415545

Biomol NMR Assign 2013 Apr;7(1):43-6

TonB-dependent transporters (TBDTs) are bacterial outer membrane proteins that internalize nutrients such as vitamin B12, metal complexes, heme, some carbohydrates, etc. In addition to their transport activity, several TBDTs are also involved in a signalling cascade from the cell surface into the cytoplasm, via their periplasmic signalling domain. Here we report the backbone and side chain resonance assignments of the signalling domain of HasR, a TonB-dependent outer membrane heme transporter from Serratia marcescens as a first step towards its structural study.

http://www.ncbi.nlm.nih.gov/pubmed/22415545