Ligne de temps

Nadia Izadi-Pruneyre
Responsable de Structure
01 avr. 2024
publication

Mechanism of action of phthalazinone derivatives against rabies virus.

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07 févr. 2024
news

Des moteurs moléculaires produisent l’énergie nécessaire pour nourrir les bactéries

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07 févr. 2024
news

Des moteurs moléculaires produisent l’énergie nécessaire pour nourrir les bactéries

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06 janv. 2024
publication

Ton motor conformational switch and peptidoglycan role in bacterial nutrient uptake.

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23 nov. 2023
publication

The Mla system of diderm Firmicute Veillonella parvula reveals an ancestral transenvelope bridge for phospholipid trafficking.

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12 nov. 2023
publication

A poly-proline II helix in YadA from Yersinia enterocolitica serotype O:9 facilitates heparin binding through electrostatic interactions.

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07 nov. 2023
publication

Structural Analysis of Proteins from Bacterial Secretion Systems and Their Assemblies by NMR Spectroscopy

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25 août 2023
event

DBSC workshop “Optimal Prediction of Protein Complex Structures with AlphaFold Made Easy” on September 26th

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02 févr. 2023
publication

Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system.

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01 févr. 2023
news

Bacterial pathogenicity: improving understanding of an essential process – molecule secretion

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27 janv. 2023
event

NMR: a tool for biology XIIIth

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11 sept. 2022
project

Energir: Comprendre les mécanismes moléculaires d’acquisition du fer chez les bactéries à Gram-négatif, par une approche intégrative

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28 avr. 2022
publication

Secondary structure and 1H, 15 N & 13C resonance assignments of the periplasmic domain of OutG, major pseudopilin from Dickeya dadantii type II secretion system.

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13 avr. 2022
publication

Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog

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16 mars 2022
event

Half-day Latest innovations and Applications in CryoEM& CryoET

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01 oct. 2021
publication

1 H, 15 N and 13 C resonance assignments of the C-terminal domain of PulL, a component of the Klebsiella oxytoca type II secretion system

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28 sept. 2021
project

ANR OM-LipAsy: Outer membrane lipid asymmetry in Veillonella parvula, an atypical diderm Firmicute

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11 sept. 2021
publication

Computational and biochemical analysis of type IV pilus dynamics and stability.

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14 juil. 2021
publication

Host-Pathogen Adhesion as the Basis of Innovative Diagnostics for Emerging Pathogens.

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22 juin 2020
event

NMR: a tool for Biology XIIth

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20 déc. 2019
event

Department of Structural Biology and Chemistry seminar: Dr. Olivier Lambert, Antibiotic resistance and contribution of Multidrug Efflux Pumps: Structural and functional insights.

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29 nov. 2019
publication

Structure and function of minor pilins of type IV pili.

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31 juil. 2019
project

Synergy_T2SS

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09 juil. 2019
news

Post-doc available

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23 mai 2019
publication

Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches

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09 avr. 2019
publication

Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus.

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26 janv. 2019
event

11th Conference “NMR: a tool for Biology”, 28-30 Jan 2019

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24 janv. 2019
patent

Docking method based on saturation transfer difference NMR data, and means for its implementation WO 2019/011987

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18 déc. 2018
publication

Target engagement and binding mode of an anti-tuberculosis drug to its bacterial target deciphered in whole living cells by NMR.

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06 avr. 2018
event

Seminar of the Department of Structural Biology and Chemistry

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05 avr. 2018
event

Inhibiting Chromatin Assembly by Targeting Histone Chaperones

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09 mars 2018
project

Protein synthesis machinery of Trypanosomatid as a therapeutic target

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27 déc. 2017
event

Dr. OCHSENBEIN Françoise – “Inhibiting Chromatin Assembly by Targeting Histone Chaperones” (CANCELLED)

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28 nov. 2017
project

ViBrANT (Viral and Bacterial Adhesin Network Training)

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01 oct. 2017
publication

1H, 15N and 13C resonance assignments and secondary structure of PulG, the major pseudopilin from Klebsiella oxytoca type 2 secretion system.

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27 mai 2016
publication

Structural basis of the signaling through a bacterial membrane receptor HasR deciphered by an integrative approach.

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09 sept. 2015
tool

Nuclear Magnetic Resonance spectrometers

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31 août 2015
project

Binding mode of promising antituberculosis clinical compounds to their bacterial target

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28 août 2015
team

Systèmes transmembranaires bactériens

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22 juil. 2015
project

FiberSpace

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07 juil. 2015
project

Bacterial Transmembrane Signaling

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01 juin 2015
publication

A tribute to Cécile Wandersman

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15 sept. 2014
department

Biologie structurale et chimie

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11 avr. 2014
publication

Interaction of a partially disordered antisigma factor with its partner, the signaling domain of the TonB-dependent transporter HasR

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19 mars 2013
publication

The structure of HasB reveals a new class of TonB protein fold

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15 déc. 2012
publication

¹H, ¹⁵N and ¹³C resonance assignments of PpdD, a type IV pilin from enterohemorrhagic Escherichia coli

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14 mars 2012
publication

(1)H, (13)C and (15)N resonance assignments of the periplasmic signalling domain of HasR, a TonB-dependent outer membrane heme transporter

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11 févr. 2009
publication

Mapping the interaction between the hemophore HasA and its outer membrane receptor HasR using CRINEPT-TROSY NMR spectroscopy.

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14 janv. 2009
publication

Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex

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28 mars 2008
publication

Modulation by substrates of the interaction between the HasR outer membrane receptor and its specific TonB-like protein, HasB

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19 janv. 2008
publication

Novel heme ligand displacement by CO in the soluble hemophore HasA and its proximal ligand mutants: implications for heme uptake and release

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04 déc. 2007
publication

Comparative analysis of structural and dynamic properties of the loaded and unloaded hemophore HasA: functional implications

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03 nov. 2007
publication

(1)H, (13)C and (15)N resonance assignments of the C-terminal domain of HasB, a specific TonB like protein, from Serratia marcescens

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04 mai 2007
publication

Mutagenesis and molecular modeling reveal three key extracellular loops of the membrane receptor HasR that are involved in hemophore HasA binding

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25 oct. 2006
publication

The crystal structure of the secreted dimeric form of the hemophore HasA reveals a domain swapping with an exchanged heme ligand

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14 juin 2006
publication

The heme transfer from the soluble HasA hemophore to its membrane-bound receptor HasR is driven by protein-protein interaction from a high to a lower affinity binding site

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01 oct. 2003
publication

Role of the tyrosine corner motif in the stability of neocarzinostatin

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01 oct. 2003
publication

Ligand delivery by haem carrier proteins: the binding of Serratia marcescens haemophore to its outer membrane receptor is mediated by two distinct peptide regions

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16 sept. 2003
publication

Thermodynamics of heme binding to the HasA(SM) hemophore: effect of mutations at three key residues for heme uptake

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01 nov. 2001
publication

Key interactions in the immunoglobulin-like structure of apo-neocarzinostatin: evidence from nuclear magnetic resonance relaxation data and molecular dynamics simulations

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01 nov. 2000
publication

Functional aspects of the heme bound hemophore HasA by structural analysis of various crystal forms

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01 mars 2000
publication

Simple and accurate determination of global tau(R) in proteins using (13)C or (15)N relaxation data

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01 janv. 2000
publication

Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease

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01 juin 1999
publication

Backbone NMR assignment and secondary structure of the 19 kDa hemophore HasA

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01 juin 1999
publication

The crystal structure of HasA, a hemophore secreted by Serratia marcescens

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01 avr. 1999
publication

NMR studies of the C-terminal secretion signal of the haem-binding protein, HasA

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10 juin 1997
publication

Purification and characterization of an extracellular heme-binding protein, HasA, involved in heme iron acquisition

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