Ligne de temps
Nadia Izadi-Pruneyre
Responsable de Structure
30 oct. 2024
publication
Dynamic interplay between a TonB-dependent heme transporter and a TonB protein in a membrane environment
Lire plus05 juil. 2024
01 avr. 2024
07 févr. 2024
07 févr. 2024
01 févr. 2024
06 janv. 2024
publication
Ton motor conformational switch and peptidoglycan role in bacterial nutrient uptake.
Lire plus23 nov. 2023
publication
The Mla system of diderm Firmicute Veillonella parvula reveals an ancestral transenvelope bridge for phospholipid trafficking.
Lire plus12 nov. 2023
publication
A poly-proline II helix in YadA from Yersinia enterocolitica serotype O:9 facilitates heparin binding through electrostatic interactions.
Lire plus07 nov. 2023
publication
Structural Analysis of Proteins from Bacterial Secretion Systems and Their Assemblies by NMR Spectroscopy
Lire plus25 août 2023
event
DBSC workshop “Optimal Prediction of Protein Complex Structures with AlphaFold Made Easy” on September 26th
Lire plus02 févr. 2023
publication
Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system.
Lire plus01 févr. 2023
news
Bacterial pathogenicity: improving understanding of an essential process – molecule secretion
Lire plus27 janv. 2023
11 sept. 2022
project
Energir: Comprendre les mécanismes moléculaires d’acquisition du fer chez les bactéries à Gram-négatif, par une approche intégrative
Lire plus28 avr. 2022
publication
Secondary structure and 1H, 15 N & 13C resonance assignments of the periplasmic domain of OutG, major pseudopilin from Dickeya dadantii type II secretion system.
Lire plus13 avr. 2022
publication
Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog
Lire plus16 mars 2022
01 oct. 2021
publication
1 H, 15 N and 13 C resonance assignments of the C-terminal domain of PulL, a component of the Klebsiella oxytoca type II secretion system
Lire plus28 sept. 2021
project
ANR OM-LipAsy: Outer membrane lipid asymmetry in Veillonella parvula, an atypical diderm Firmicute
Lire plus11 sept. 2021
publication
Computational and biochemical analysis of type IV pilus dynamics and stability.
Lire plus14 juil. 2021
publication
Host-Pathogen Adhesion as the Basis of Innovative Diagnostics for Emerging Pathogens.
Lire plus22 juin 2020
20 déc. 2019
event
Department of Structural Biology and Chemistry seminar: Dr. Olivier Lambert, Antibiotic resistance and contribution of Multidrug Efflux Pumps: Structural and functional insights.
Lire plus29 nov. 2019
31 juil. 2019
09 juil. 2019
23 mai 2019
publication
Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches
Lire plus09 avr. 2019
publication
Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus.
Lire plus26 janv. 2019
24 janv. 2019
patent
Docking method based on saturation transfer difference NMR data, and means for its implementation WO 2019/011987
Lire plus18 déc. 2018
publication
Target engagement and binding mode of an anti-tuberculosis drug to its bacterial target deciphered in whole living cells by NMR.
Lire plus06 avr. 2018
05 avr. 2018
09 mars 2018
27 déc. 2017
event
Dr. OCHSENBEIN Françoise – “Inhibiting Chromatin Assembly by Targeting Histone Chaperones” (CANCELLED)
Lire plus28 nov. 2017
01 oct. 2017
publication
1H, 15N and 13C resonance assignments and secondary structure of PulG, the major pseudopilin from Klebsiella oxytoca type 2 secretion system.
Lire plus27 mai 2016
publication
Structural basis of the signaling through a bacterial membrane receptor HasR deciphered by an integrative approach.
Lire plus09 sept. 2015
31 août 2015
project
Binding mode of promising antituberculosis clinical compounds to their bacterial target
Lire plus28 août 2015
22 juil. 2015
07 juil. 2015
01 juin 2015
15 sept. 2014
11 avr. 2014
publication
Interaction of a partially disordered antisigma factor with its partner, the signaling domain of the TonB-dependent transporter HasR
Lire plus19 mars 2013
15 déc. 2012
publication
¹H, ¹⁵N and ¹³C resonance assignments of PpdD, a type IV pilin from enterohemorrhagic Escherichia coli
Lire plus14 mars 2012
publication
(1)H, (13)C and (15)N resonance assignments of the periplasmic signalling domain of HasR, a TonB-dependent outer membrane heme transporter
Lire plus11 févr. 2009
publication
Mapping the interaction between the hemophore HasA and its outer membrane receptor HasR using CRINEPT-TROSY NMR spectroscopy.
Lire plus14 janv. 2009
publication
Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex
Lire plus28 mars 2008
publication
Modulation by substrates of the interaction between the HasR outer membrane receptor and its specific TonB-like protein, HasB
Lire plus19 janv. 2008
publication
Novel heme ligand displacement by CO in the soluble hemophore HasA and its proximal ligand mutants: implications for heme uptake and release
Lire plus04 déc. 2007
publication
Comparative analysis of structural and dynamic properties of the loaded and unloaded hemophore HasA: functional implications
Lire plus03 nov. 2007
publication
(1)H, (13)C and (15)N resonance assignments of the C-terminal domain of HasB, a specific TonB like protein, from Serratia marcescens
Lire plus04 mai 2007
publication
Mutagenesis and molecular modeling reveal three key extracellular loops of the membrane receptor HasR that are involved in hemophore HasA binding
Lire plus25 oct. 2006
publication
The crystal structure of the secreted dimeric form of the hemophore HasA reveals a domain swapping with an exchanged heme ligand
Lire plus14 juin 2006
publication
The heme transfer from the soluble HasA hemophore to its membrane-bound receptor HasR is driven by protein-protein interaction from a high to a lower affinity binding site
Lire plus01 oct. 2003
01 oct. 2003
publication
Ligand delivery by haem carrier proteins: the binding of Serratia marcescens haemophore to its outer membrane receptor is mediated by two distinct peptide regions
Lire plus16 sept. 2003
publication
Thermodynamics of heme binding to the HasA(SM) hemophore: effect of mutations at three key residues for heme uptake
Lire plus01 nov. 2001
publication
Key interactions in the immunoglobulin-like structure of apo-neocarzinostatin: evidence from nuclear magnetic resonance relaxation data and molecular dynamics simulations
Lire plus01 nov. 2000
publication
Functional aspects of the heme bound hemophore HasA by structural analysis of various crystal forms
Lire plus01 mars 2000
publication
Simple and accurate determination of global tau(R) in proteins using (13)C or (15)N relaxation data
Lire plus01 janv. 2000
01 juin 1999
01 juin 1999
01 avr. 1999
publication
NMR studies of the C-terminal secretion signal of the haem-binding protein, HasA
Lire plus10 juin 1997
publication