Timeline

Vincenzo Di Bartolo
Group Leader
07 Mar 2019
project

Projet de Recherche Clinique : Impact des mutations du gène APC (Adenomatous polyposis coli) dans les réponses immunes anti-tumorales

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30 Oct 2018
news

Recrutement de patients atteints de polypose familiale porteurs de mutation du gène APC

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12 Oct 2018
project

CoSImmGEn-F : constitution d’une cohorte de sujets atteints de polypose adénomateuse familiale et porteurs d’une mutation du gène APC afin d’étudier le rôle de la génétique du système immunitaire et de l’environnement dans la maladie

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24 Feb 2017
publication

Rab11-FIP3 Regulation of Lck Endosomal Traffic Controls TCR Signal Transduction

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20 Jan 2017
publication

Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function

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22 Jun 2016
project

Think tank: Cancer

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06 May 2016
publication

Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation

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28 Jan 2016
publication

Comparative Anatomy of Phagocytic and Immunological Synapses

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16 Jul 2015
team

Group: Lymphocyte Signaling and Activation

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07 Jul 2015
project

How the dynamics of signaling complexes at the immunological synapse controls T cell activation

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06 Jul 2015
project

Cytoskeleton, immunological synapse and T cell activation: role of Ezrin and Adenomatous polyposis coli

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11 May 2015
team

Lymphocyte Cell Biology

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21 Nov 2011
publication

Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation

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18 Jul 2011
publication

Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression

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21 Apr 2011
publication

The Shigella flexneri type three secretion system effector IpgD inhibits T cell migration by manipulating host phosphoinositide metabolism

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15 Jun 2010
publication

Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse

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30 Dec 2009
publication

Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events

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01 Sep 2008
publication

Tailoring T-cell receptor signals by proximal negative feedback mechanisms

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12 Mar 2007
publication

A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76

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11 Jan 2007
publication

ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation

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01 Dec 2005
publication

CD8 T cell sensory adaptation dependent on TCR avidity for self-antigens

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01 Feb 2005
publication

Sequence tag scanning: a new explorative strategy for recognition of unexpected protein alterations by nanoelectrospray ionization-tandem mass spectrometry

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01 Aug 2004
publication

Large-scale screening for genes involved in T-cell signaling: do we know all the players now?

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01 Apr 2004
publication

T-cell receptor-induced phosphorylation of the zeta chain is efficiently promoted by ZAP-70 but not Syk

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01 Sep 2003
publication

Proximal changes in signal transduction that modify CD8+ T cell responsiveness in vivo

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01 Jan 2003
publication

Induction of the NF-kappaB cascade by recruitment of the scaffold molecule NEMO to the T cell receptor

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01 Oct 2002
publication

In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern

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15 Aug 2002
publication

TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70

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01 Feb 2002
publication

Tyrosine 315 determines optimal recruitment of ZAP-70 to the T cell antigen receptor

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20 Aug 2001
publication

T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase

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18 Jun 2001
publication

Functional dichotomy in natural killer cell signaling: Vav1-dependent and -independent mechanisms

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25 Oct 1999
publication

The Rift Valley fever virus nonstructural protein NSs is phosphorylated at serine residues located in casein kinase II consensus motifs in the carboxy-terminus

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15 Aug 1999
publication

Redundant role of the Syk protein tyrosine kinase in mouse NK cell differentiation

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14 May 1999
publication

Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck

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01 Mar 1999
publication

Tyrosine 319, a newly identified phosphorylation site of ZAP-70, plays a critical role in T cell antigen receptor signaling

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15 Sep 1998
publication

An improved retroviral gene transfer technique demonstrates inhibition of CD4-CD8- thymocyte development by kinase-inactive ZAP-70

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01 Jan 1997
publication

Further evidence for an endogenous digitalis-like compound in newborn and adult plasma detected by anti-ouabain antiserum

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20 Dec 1996
publication

Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways

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01 Jan 1996
publication

Binding of human GM-CSF to synthetic peptides of the alpha subunit of its receptor

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01 Jun 1995
publication

The stimulatory effect on human erythrocyte rubidium-86 uptake by anti-cardiac-glycoside antibodies

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27 Feb 1995
publication

Autoantibodies directed against ribosomal P proteins: use of a multiple antigen peptide as the coating agent in ELISA

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01 Jan 1995
publication

Evidence for an endogenous ouabain-like immunoreactive factor in human newborn plasma coeluted with ouabain on HPLC

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01 Dec 1994
publication

An immunodominant epitope in a functional domain near the N-terminus of human granulocyte-macrophage colony-stimulating factor identified by cross-reaction of synthetic peptides with neutralizing anti-protein and anti-peptide antibodies

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01 Jul 1993
publication

BQ-123 inhibits both endothelin 1 and endothelin 3 mediated C6 rat glioma cell proliferation suggesting an atypical endothelin receptor

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