Ligne de temps
Vincenzo Di Bartolo
Chercheur(euse) Permanent(e)
23 oct. 2024
05 mars 2024
publication
Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids
Lire plus18 juil. 2023
publication
T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations
Lire plus15 avr. 2022
news
New publication – The tumor suppressor Adenomatous polyposis coli regulates T lymphocyte migration
Lire plus15 avr. 2022
publication
The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration.
Lire plus06 oct. 2021
publication
Cell Polarity Regulators, Multifunctional Organizers of Lymphocyte Activation and Function.
Lire plus21 oct. 2020
publication
Coordinating Cytoskeleton and Molecular Traffic in T Cell Migration, Activation, and Effector Functions.
Lire plus24 juin 2020
publication
Adenomatous Polyposis Coli Modulates Actin and Microtubule Cytoskeleton at the Immunological Synapse to Tune CTL Functions.
Lire plus10 mars 2020
publication
ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation.
Lire plus01 juil. 2019
publication
Histamine releasing factor and elongation factor 1 alpha secreted via malaria parasites extracellular vesicles promote immune evasion by inhibiting specific T cell responses.
Lire plus07 mars 2019
project
Projet de Recherche Clinique : Impact des mutations du gène APC (Adenomatous polyposis coli) dans les réponses immunes anti-tumorales
Lire plus12 oct. 2018
project
CoSImmGEn-F : constitution d’une cohorte de sujets atteints de polypose adénomateuse familiale et porteurs d’une mutation du gène APC afin d’étudier le rôle de la génétique du système immunitaire et de l’environnement dans la maladie
Lire plus03 oct. 2018
publication
HIV-1 Nef Hijacks Lck and Rac1 Endosomal Traffic To Dually Modulate Signaling-Mediated and Actin Cytoskeleton-Mediated T Cell Functions.
Lire plus26 avr. 2018
03 oct. 2017
publication
Adenomatous Polyposis Coli Defines Treg Differentiation and Anti-inflammatory Function through Microtubule-Mediated NFAT Localization.
Lire plus24 févr. 2017
publication
Rab11-FIP3 Regulation of Lck Endosomal Traffic Controls TCR Signal Transduction.
Lire plus20 janv. 2017
publication
Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function.
Lire plus22 juin 2016
06 mai 2016
publication
Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation.
Lire plus28 janv. 2016
01 janv. 2016
07 juil. 2015
project
How the dynamics of signaling complexes at the immunological synapse controls T cell activation
Lire plus06 juil. 2015
project
Cytoskeleton, immunological synapse and T cell activation: role of Ezrin and Adenomatous polyposis coli
Lire plus11 mai 2015
21 nov. 2011
publication
Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation.
Lire plus18 juil. 2011
publication
Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression.
Lire plus21 avr. 2011
publication
The Shigella flexneri type three secretion system effector IpgD inhibits T cell migration by manipulating host phosphoinositide metabolism.
Lire plus15 juin 2010
publication
Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse.
Lire plus30 déc. 2009
publication
Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events.
Lire plus01 sept. 2008
19 mars 2007
publication
A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76.
Lire plus11 janv. 2007
publication
ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation.
Lire plus01 déc. 2005
01 févr. 2005
publication
Sequence tag scanning: a new explorative strategy for recognition of unexpected protein alterations by nanoelectrospray ionization-tandem mass spectrometry
Lire plus01 août 2004
publication
Large-scale screening for genes involved in T-cell signaling: do we know all the players now?
Lire plus01 avr. 2004
publication
T-cell receptor-induced phosphorylation of the zeta chain is efficiently promoted by ZAP-70 but not Syk
Lire plus01 sept. 2003
publication
Proximal changes in signal transduction that modify CD8+ T cell responsiveness in vivo
Lire plus01 janv. 2003
publication
Induction of the NF-kappaB cascade by recruitment of the scaffold molecule NEMO to the T cell receptor
Lire plus01 oct. 2002
publication
In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern
Lire plus15 août 2002
01 févr. 2002
publication
Tyrosine 315 determines optimal recruitment of ZAP-70 to the T cell antigen receptor.
Lire plus20 août 2001
publication
T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase
Lire plus18 juin 2001
publication
Functional dichotomy in natural killer cell signaling: Vav1-dependent and -independent mechanisms
Lire plus25 oct. 1999
publication
The Rift Valley fever virus nonstructural protein NSs is phosphorylated at serine residues located in casein kinase II consensus motifs in the carboxy-terminus.
Lire plus15 août 1999
publication
Redundant role of the Syk protein tyrosine kinase in mouse NK cell differentiation
Lire plus14 mai 1999
publication
Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck.
Lire plus05 mars 1999
publication
Tyrosine 319, a newly identified phosphorylation site of ZAP-70, plays a critical role in T cell antigen receptor signaling.
Lire plus15 sept. 1998
publication
An improved retroviral gene transfer technique demonstrates inhibition of CD4-CD8- thymocyte development by kinase-inactive ZAP-70
Lire plus01 janv. 1997
publication
Further evidence for an endogenous digitalis-like compound in newborn and adult plasma detected by anti-ouabain antiserum
Lire plus20 déc. 1996
publication
Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways.
Lire plus01 janv. 1996
publication
Binding of human GM-CSF to synthetic peptides of the alpha subunit of its receptor
Lire plus01 juin 1995
publication
The stimulatory effect on human erythrocyte rubidium-86 uptake by anti-cardiac-glycoside antibodies
Lire plus27 févr. 1995
publication
Autoantibodies directed against ribosomal P proteins: use of a multiple antigen peptide as the coating agent in ELISA
Lire plus01 janv. 1995
publication
Evidence for an endogenous ouabain-like immunoreactive factor in human newborn plasma coeluted with ouabain on HPLC
Lire plus01 déc. 1994
publication
An immunodominant epitope in a functional domain near the N-terminus of human granulocyte-macrophage colony-stimulating factor identified by cross-reaction of synthetic peptides with neutralizing anti-protein and anti-peptide antibodies
Lire plus01 juil. 1993
publication