Ligne de temps

Vincenzo Di Bartolo
Chercheur(euse) Permanent(e)
05 mars 2024
publication

Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids

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18 juil. 2023
publication

T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations

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15 avr. 2022
news

New publication – The tumor suppressor Adenomatous polyposis coli regulates T lymphocyte migration

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15 avr. 2022
publication

The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration.

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06 oct. 2021
publication

Cell Polarity Regulators, Multifunctional Organizers of Lymphocyte Activation and Function.

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21 oct. 2020
publication

Coordinating Cytoskeleton and Molecular Traffic in T Cell Migration, Activation, and Effector Functions.

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24 juin 2020
publication

Adenomatous Polyposis Coli Modulates Actin and Microtubule Cytoskeleton at the Immunological Synapse to Tune CTL Functions.

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10 mars 2020
publication

ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation.

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01 juil. 2019
publication

Histamine releasing factor and elongation factor 1 alpha secreted via malaria parasites extracellular vesicles promote immune evasion by inhibiting specific T cell responses.

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07 mars 2019
project

Projet de Recherche Clinique : Impact des mutations du gène APC (Adenomatous polyposis coli) dans les réponses immunes anti-tumorales

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12 oct. 2018
project

CoSImmGEn-F : constitution d’une cohorte de sujets atteints de polypose adénomateuse familiale et porteurs d’une mutation du gène APC afin d’étudier le rôle de la génétique du système immunitaire et de l’environnement dans la maladie

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03 oct. 2018
publication

HIV-1 Nef Hijacks Lck and Rac1 Endosomal Traffic To Dually Modulate Signaling-Mediated and Actin Cytoskeleton-Mediated T Cell Functions.

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26 avr. 2018
publication

Cell Biology of T Cell Receptor Expression and Regulation.

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03 oct. 2017
publication

Adenomatous Polyposis Coli Defines Treg Differentiation and Anti-inflammatory Function through Microtubule-Mediated NFAT Localization.

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24 févr. 2017
publication

Rab11-FIP3 Regulation of Lck Endosomal Traffic Controls TCR Signal Transduction.

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20 janv. 2017
publication

Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function.

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22 juin 2016
project

Think tank: Cancer

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06 mai 2016
publication

Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation.

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28 janv. 2016
publication

Comparative Anatomy of Phagocytic and Immunological Synapses.

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01 janv. 2016
publication

Editorial: Molecular Dynamics at the Immunological Synapse.

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07 juil. 2015
project

How the dynamics of signaling complexes at the immunological synapse controls T cell activation

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06 juil. 2015
project

Cytoskeleton, immunological synapse and T cell activation: role of Ezrin and Adenomatous polyposis coli

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11 mai 2015
team

Immunorégulation

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21 nov. 2011
publication

Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation.

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18 juil. 2011
publication

Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression.

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21 avr. 2011
publication

The Shigella flexneri type three secretion system effector IpgD inhibits T cell migration by manipulating host phosphoinositide metabolism.

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15 juin 2010
publication

Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse.

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30 déc. 2009
publication

Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events.

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01 sept. 2008
publication

Tailoring T-cell receptor signals by proximal negative feedback mechanisms.

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19 mars 2007
publication

A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76.

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11 janv. 2007
publication

ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation.

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01 déc. 2005
publication

CD8 T cell sensory adaptation dependent on TCR avidity for self-antigens.

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01 févr. 2005
publication

Sequence tag scanning: a new explorative strategy for recognition of unexpected protein alterations by nanoelectrospray ionization-tandem mass spectrometry

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01 août 2004
publication

Large-scale screening for genes involved in T-cell signaling: do we know all the players now?

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01 avr. 2004
publication

T-cell receptor-induced phosphorylation of the zeta chain is efficiently promoted by ZAP-70 but not Syk

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01 sept. 2003
publication

Proximal changes in signal transduction that modify CD8+ T cell responsiveness in vivo

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01 janv. 2003
publication

Induction of the NF-kappaB cascade by recruitment of the scaffold molecule NEMO to the T cell receptor

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01 oct. 2002
publication

In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern

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15 août 2002
publication

TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70.

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01 févr. 2002
publication

Tyrosine 315 determines optimal recruitment of ZAP-70 to the T cell antigen receptor.

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20 août 2001
publication

T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase

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18 juin 2001
publication

Functional dichotomy in natural killer cell signaling: Vav1-dependent and -independent mechanisms

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25 oct. 1999
publication

The Rift Valley fever virus nonstructural protein NSs is phosphorylated at serine residues located in casein kinase II consensus motifs in the carboxy-terminus.

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15 août 1999
publication

Redundant role of the Syk protein tyrosine kinase in mouse NK cell differentiation

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14 mai 1999
publication

Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck.

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05 mars 1999
publication

Tyrosine 319, a newly identified phosphorylation site of ZAP-70, plays a critical role in T cell antigen receptor signaling.

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15 sept. 1998
publication

An improved retroviral gene transfer technique demonstrates inhibition of CD4-CD8- thymocyte development by kinase-inactive ZAP-70

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01 janv. 1997
publication

Further evidence for an endogenous digitalis-like compound in newborn and adult plasma detected by anti-ouabain antiserum

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20 déc. 1996
publication

Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways.

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01 janv. 1996
publication

Binding of human GM-CSF to synthetic peptides of the alpha subunit of its receptor

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01 juin 1995
publication

The stimulatory effect on human erythrocyte rubidium-86 uptake by anti-cardiac-glycoside antibodies

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27 févr. 1995
publication

Autoantibodies directed against ribosomal P proteins: use of a multiple antigen peptide as the coating agent in ELISA

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01 janv. 1995
publication

Evidence for an endogenous ouabain-like immunoreactive factor in human newborn plasma coeluted with ouabain on HPLC

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01 déc. 1994
publication

An immunodominant epitope in a functional domain near the N-terminus of human granulocyte-macrophage colony-stimulating factor identified by cross-reaction of synthetic peptides with neutralizing anti-protein and anti-peptide antibodies

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01 juil. 1993
publication

BQ-123 inhibits both endothelin 1 and endothelin 3 mediated C6 rat glioma cell proliferation suggesting an atypical endothelin receptor

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