My interest lies in the study of structure-function properties of synaptic ligand-gated ion channels, through functional approaches combining electrophysiology, molecular biology, pharmacology and thiol-modifying biochemistry. I am now exploring further this axis with structural […]
My focus is on the basic molecular mechanisms involved in neuronal signaling. Specifically I study the pentameric ligand-gated ion channel (pLGIC) family of receptors and the relationship between their structure and function. My […]
Dr. Sadri ZNAIDI is a biochemist (B.Sc., M.Sc. from the University of Sherbrooke, Canada) and molecular biologist (Ph.D., from the University of Montreal, Canada), with expertise in yeast genetics and functional genomics. He is […]
I did my Master and my PhD in the NMR unit of Biomolecules headed by Mrs. Delepierre at the Institut Pasteur. My thesis focused on the study of heme acquisition mechanism in bacteria. I […]
Using a combination of cutting edge microscopy techniques, I am investigating the physical mechanisms responsible for intermediate filaments dynamics in migrating cells and how they are controlled.
I investigate the potential role of the microtubule acetylation, a posttranslational modification, known to mark stable, long-lived microtubules, in the regulation of the dynamics of focal adhesion during collective migration of primary astrocytes in […]
Innate immunity and Leptospira La leptospirose est une zoonoose réémergente, négligée et de répartition mondiale, causée par des bactéries pathogènes incluant l’espèce Leptospira interrogans. Ces bactéries spiralées et motiles pénètrent leur hôte par la […]