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Quality Control at the Ribosome
Micheline Fromont-Racine (PI)
Gene expression is controlled and regulated by nuclear and cytoplasmic surveillance mechanisms in order to preserve the integrity of genetic information. Some of the mechanisms occur in the nucleus during transcription and maturation of […]
2019A specialised SKI complex assists the cytoplasmic RNA exosome in the absence of direct association with ribosomes, EMBO J. 2019 Jun;.
2018Nonsense-mediated mRNA decay involves two distinct Upf1-bound complexes, EMBO J. 2018 Oct;.
2017The Ribosome-bound Quality Control complex remains associated to aberrant peptides during their proteasomal targeting and interacts with Tom1 to limit protein aggregation, Mol. Biol. Cell 2017 ;28(9):1165-1176.
2016The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex, Science 2016 Dec;354(6318):1431-1433.
2016Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins, Nat Commun 2016 Dec;7:13582.
2016Role of the N-Acetylmuramoyl-l-Alanyl Amidase, AmiA, of Helicobacter pylori in Peptidoglycan Metabolism, Daughter Cell Separation, and Virulence, Microb. Drug Resist. 2016 Sep;22(6):477-86.
2016Rqc1 and Ltn1 prevent CAT-tail induced protein aggregation by efficient recruitment of Cdc48 on stalled 60S subunits, J. Biol. Chem. 2016;291(23):12245-53..
2014Proteomic analysis of intact flagella of procyclic Trypanosoma brucei cells identifies novel flagellar proteins with unique sub-localization and dynamics, Mol. Cell Proteomics 2014 Jul;13(7):1769-86.
2014Isolation, functional characterization and proteomic identification of CC2-PLA₂ from Cerastes cerastes venom: a basic platelet-aggregation-inhibiting factor, Protein J. 2014 Feb;33(1):61-74.
2013Differential expression of Ixodes ricinus salivary gland proteins in the presence of the Borrelia burgdorferi sensu lato complex, J Proteomics 2014 Jan;96:29-43.
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