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  • tool
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  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
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  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
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  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
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Projects

Project
Ongoing
5 Members

Cytoplasmic mRNA degradation pathways

Micheline Fromont-Racine (PI)

Cellular mRNAs are subjected to a balance between synthesis and degradation, which determines the shape of the transcriptome and greatly participates to protein homeostasis. In addition to the general degradation pathways, which ensure the […]
Project
Ongoing
7 Members

Translation and Ribosome rescue

Micheline Fromont-Racine (PI)

Translation involves four main steps: initiation, elongation, termination and recycling. Each step is highly controlled and can be modulated depending on the mRNA characteristics. The first step begins with the binding of eIF3 to […]
Project
Ongoing
4 Members

Quality Control at the Ribosome

Micheline Fromont-Racine (PI)

Gene expression is controlled and regulated by nuclear and cytoplasmic surveillance mechanisms in order to preserve the integrity of genetic information. Some of the mechanisms occur in the nucleus during transcription and maturation of […]
Project
Ongoing
7 Members

Non-sense mediated mRNA decay mechanisms

Cosmin Saveanu (PI)

Non-sense mediated mRNA decay (NMD) is a fundamental and conserved mechanism with a major role in shaping the levels of individual RNAs in a eukaryotic cell by efficiently removing RNAs in which a stop […]

Publications

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