Dr. Sadri ZNAIDI is a biochemist (B.Sc., M.Sc. from the University of Sherbrooke, Canada) and molecular biologist (Ph.D., from the University of Montreal, Canada), with expertise in yeast genetics and functional genomics. He is currently a RIIP (Institut Pasteur International Network) Affiliate Program Fellow, with affiliations at the Institut Pasteur in Tunis and Paris. His current work focuses on the implementation of systems biology-oriented approaches to identify and characterize components of the biological circuitry involved in the interaction of Candida albicans with the host environment.
Candida albicans colonization of abiotic and biotic surfaces
Biofilms formed by C. albicans on indwelling devices play a major role in the persistence of nosocomial infections, largely because of their elevated tolerance to antifungals. The Fungal Biology and Pathogenicity Unit at Institut […]
Regulation of Candida albicans morphogenesis
The Fungal Biology and Pathogenicity Unit at Institut Pasteur is interested in the regulation of the yeast-to-hypha transition in C. albicans because of its role in biofilm formation and, more generally, in virulence. While […]
FunComPath is a network within the Infect-ERA programme (www.infect-era.eu). Infect-ERA is an ERA-Net on human infectious diseases funded under the EU 7th Research Framework Programme (2013 – 2016). It is a continuation of the […]
Current: RIIP Affiliate Program Fellow, Institut Pasteur in Tunis & Paris
2010 – 2015: Postdoctoral fellow, Institut Pasteur, Paris, France
2004 – 2010: Ph.D., Molecular Biology, University of Montreal, Canada
2002 – 2004: M.Sc., Biochemistry, Université de Sherbrooke, Canada
1999 – 2002: B.Sc., Biochemistry, Université de Sherbrooke, Canada
2021Ethylzingerone, a Novel Compound with Antifungal Activity., Antimicrob Agents Chemother 2021 03; 65(4): .
2021High Frequency of Enterocytozoon bieneusi Genotype WL12 Occurrence among Immunocompromised Patients with Intestinal Microsporidiosis., J Fungi (Basel) 2021 Feb; 7(3): .
2020A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans., Nat Commun 2020 12; 11(1): 6224.
2020mSphere of Influence: Decoding Transcriptional Regulatory Networks To Illuminate the Mechanisms of Microbial Pathogenicity., mSphere 2020 01; 5(1): .
2020Identification and Characterization of Mediators of Fluconazole Tolerance in Candida albicans., Front Microbiol 2020 ; 11(): 591140.
2019From Genes to Networks: The Regulatory Circuitry Controlling Candida albicans Morphogenesis., Curr Top Microbiol Immunol 2019 ; 422(): 61-99.
2018A conserved fungal hub protein involved in adhesion and drug resistance in the human pathogen Candida albicans., Cell Surf 2018 Dec; 4(): 10-19.
2018Generating genomic platforms to study Candida albicans pathogenesis., Nucleic Acids Res 2018 08; 46(14): 6935-6949.
2018Systematic gene overexpression in Candida albicans identifies a regulator of early adaptation to the mammalian gut., Cell Microbiol 2018 Nov; 20(11): e12890.
2017The two-component response regulator Skn7 belongs to a network of transcription factors regulating morphogenesis in Candida albicans and independently limits morphogenesis-induced ROS accumulation., Mol Microbiol 2017 Oct; 106(1): 157-182.
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