In the lab, we are focusing on bacterial mechanisms of survival in hostile environments containing sub-lethal antibiotic concentrations. The emergence of antibiotic resistance is increasingly associated with low antibiotic concentrations in the aquatic environment, […]
Sigolène MEILHAC is a developmental biologist and INSERM Research Director, leading since 2015 the team of Heart Morphogenesis jointly affiliated to the Institut Pasteur and Institut Imagine. Trained at the Ecole Normale Supérieure, she […]
The emergence of discrete cell identities from undifferentiated precursor cells is a central process in development and tissue homeostasis and repair, that when defective is at the basis of many human conditions including cancer […]
Born and bred in Alsace, France, I did my PhD at the Institut de Biologie Moleculaire et Cellulaire of Strasbourg, in the laboratory of Prof. Jules Hoffmann under the supervision of Dr. Dominique Ferrandon. […]
Intracellular traffic and cell compartmentalization Eukaryotic cells contain extensive internal membranes defining many compartments having each specific functions. However these organelles are constantly moving and reshaping, still retaining their identity. The maintenance of cell […]
Since the beginning of my career, my goal has been to understand the mechanisms of effector immune responses to viruses and the related viral countermeasures. During my thesis, I studied the origin of type […]
Dr. Gerald Späth currently holds a Research Director position at the Institut Pasteur in Paris, where he directs the Unit ‘Parasitologie moléculaire et Signalisation’ (12 members) and the Department ‘Parasites and Insect Vectors’ (ca. […]
Dr. Najma Rachidi is a senior Researcher and the leader of the molecular parasitology team in the PARSIG unit. Her team investigates Host-pathogen interactions to (i) understand how Leishmania survives in immune cells, which […]
Bernd Jagla is a chemist turned bioinformatician currently working on a R/Shiny application for single-cell RNAseq data analysis called SCHNAPPs, as well as unsupervised cytometry data analysis concentrating on the application of self-organizing maps […]
Immune responses are highly coordinated processes that develop within complex tissue microenvironments. The research in our Department aims to uncover novel mechanisms regulating the development and functions of the immune system with the objective […]