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  • Director of Center
  • Director of Department
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© Research
Laboratory Junior Group (G5) /

Comparative functional genomics

Department of Genomes and Genetics

About

The Comparative Functional Genomics G5 group investigates how evolutionary innovations arise in vertebrate genomes through changes in gene sequences, gene expression and gene regulation. Our main model is the evolution of menstruation, a reproductive trait which was acquired during the evolution of primates, which we investigate by comparing primate uterus samples with a combination of single-cell functional assays and computational analysis. We also develop bioinformatics models and frameworks to study how gene expression and regulation changes through time, and cellular models to test how evolutionary changes in gene function result in measurable molecular phenotypes.

Publications

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