Camille Berthelot wants to understand how changes in gene expression and gene regulation can result in the acquisition of new traits and diseases along evolution. During her PhD at ENS Paris, she examined the dynamics of chromosomal rearrangements in mammals to understand how natural selection acts on genome structures. She then joined the Flicek lab at EMBL-EBI in Cambridge as a postdoc to investigate how gene regulation has evolved across 100 million years of mammalian evolution. In 2019, she obtained an ERC Starting Grant to illuminate the mechanisms behind the acquisition of menstruation in primates, and more generally how the uterine mucosa has changed functionally across mammals. Camille is a research associate at the French National Institute of Health and Medical Research, and she currently heads the Comparative Functional Genomics lab at Institut Pasteur in Paris.
Endometriosis is a chronic gynecologic disease that occurs when endometrial tissue, which normally lines the inside of the uterus, grows outside of the uterine cavity. Endometriosis is thought to develop when endometrial fragments contained […]
ERC-2019 – StG – EVOMENS
Decoding the genetics of menstruation evolution in primates The shedding of the superficial endometrium (menstruation) is a recent evolutionary attribute. It occurs only in few placental mammals (including humans and baboons), when in most […]
- from Sept 2021 : G5 junior group leader, Institut Pasteur
- 2016 – 2021 : INSERM research scientist, Institut de Biologie de l’Ecole Normale Supérieure, Paris, France – DYOGEN lab (head: Dr Hugues Roest Crollius)
- 2012 – 2015 : Postdoctoral fellow, EMBL-EBI, Cambridge, UK – Vertebrate Functional Genomics (head: Dr Paul Flicek)
- 2009 – 2012 : Ph.D student, Institut de Biologie de l’Ecole Normale Supérieure, Paris, France – Supervisor: Dr Hugues Roest Crollius
2023Genome structures resolve the early diversification of teleost fishes., Science 2023 Feb; 379(6632): 572-575.
2023Reconstruction of hundreds of reference ancestral genomes across the eukaryotic kingdom., Nat Ecol Evol 2023 Jan; (): .
2022An atlas of fish genome evolution reveals delayed rediploidization following the teleost whole-genome duplication., Genome Res 2022 Aug; (): .
2022Classification of non-coding variants with high pathogenic impact., PLoS Genet 2022 Apr; 18(4): e1010191.
2021The bowfin genome illuminates the developmental evolution of ray-finned fishes., Nat Genet 2021 09; 53(9): 1373-1384.
2020Synteny-Guided Resolution of Gene Trees Clarifies the Functional Impact of Whole-Genome Duplications., Mol Biol Evol 2020 11; 37(11): 3324-3337.
2019Adaptation of Proteins to the Cold in Antarctic Fish: A Role for Methionine?, Genome Biol Evol 2019 01; 11(1): 220-231.
2018Chromosome evolution at the origin of the ancestral vertebrate genome., Genome Biol 2018 10; 19(1): 166.
2018Complexity and conservation of regulatory landscapes underlie evolutionary resilience of mammalian gene expression., Nat Ecol Evol 2018 Jan; 2(1): 152-163.
2017Evolution of gene expression after whole-genome duplication: New insights from the spotted gar genome., J Exp Zool B Mol Dev Evol 2017 Nov; 328(7): 709-721.
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