Project
Medicinal Chemistry [54]
Project
Alkoxypyrazoles, new chemical entities
Group
Group: Biochemistry and chemobiology
Hélène Munier-Lehmann
2015
Publication
Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)
Journal of medicinal chemistry
Lucas-Hourani M, Munier-Lehmann H, El Mazouni F, Malmquist NA, Harpon J, Coutant EP, Guillou S, Helynck O, Noel A, Scherf A, Phillips MA, Tangy F, Vidalain PO, Janin YL
Platform
Chemogenomic and Biological Screening Platform (PF-CCB)
Fabrice Agou
Laboratory
Trypanosomatids Infectious Processes
Paola Minoprio
Laboratory
Chemistry of Biomolecules
Laurence Mulard
Laboratory
Integrative Neurobiology of Cholinergic Systems
Uwe Maskos
Full Professor
Permanent Researcher
Olivier Dussurget
Group : Bacterial Pathogenesis and Antibacterial Agents
In a globalized world heading for a post-antibiotic era, refined understanding of human, animal and environmental interactions with pathogenic bacteria is of utmost importance. The primary aim of our research is to discover bacterial […]
Permanent Researcher
Laurence Mulard
Group: Carbohydrates and Bioconjugates
Associate Professor
Permanent Researcher
Sylvie Pochet
Permanent Researcher
Sophie Vichier-Guerre
Epigenetic Chemical Biology
Department
Structural Biology and Chemistry
The scientists, engineers, technicians, students and postdoctoral fellows in the Structural Biology and Chemistry Department study complex biological systems through a range of integrated approaches. We use observational techniques, experimentation and cutting-edge tools to […]
2014
Publication
Synthesis of novel 9-aryl and heteroarylpurine derivatives via copper mediated coupling reaction
Tetrahedron Letters
Laurence Morellato, Valérie Huteau and Sylvie Pochet
2010
Publication
ATPase inhibitors of heat-shock protein 90, second season
Drug discovery today
Janin YL
2009
Publication