Tool Nuclear Magnetic Resonance spectrometers Muriel Delepierre • Iñaki Guijarro • Florence Cordier • Nicolas Wolff • Nadia Izadi-Pruneyre • Bruno Vitorge
Project Binding mode of promising antituberculosis clinical compounds to their bacterial target Nadia Izadi-Pruneyre
Project Design and optimization of new bioluminescent systems better-suited to in cellulo and in vivo conditions
Project Inhibitors of the 2’-deoxyribonucleotide N-hydrolase DNPH1, an enzyme involved in cellular growth and angiogenesis Sylvie Pochet • Pierre Alexandr Kaminski
2015 Publication Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH) Journal of medicinal chemistry Lucas-Hourani M, Munier-Lehmann H, El Mazouni F, Malmquist NA, Harpon J, Coutant EP, Guillou S, Helynck O, Noel A, Scherf A, Phillips MA, Tangy F, Vidalain PO, Janin YL
Full Professor Permanent Researcher Olivier Dussurget Group : Bacterial Pathogenesis and Antibacterial Agents In a globalized world heading for a post-antibiotic era, refined understanding of human, animal and environmental interactions with pathogenic bacteria is of utmost importance. The primary aim of our research is to discover bacterial […]