Immunology [573]
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Immunology
Immune responses are highly coordinated processes that develop within complex tissue microenvironments. The research in our Department aims to uncover novel mechanisms regulating the development and functions of the immune system with the objective […]
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Parasites and Insect Vectors
The Parasites and Insect Vectors Department investigates the life cycle of parasites and their vectors. This research addresses global public health concerns and tackles the ongoing need for better prevention, control, and treatment. The department […]
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Genomes and Genetics
The teams of the department Genomes & Genetics are interested by questions related to gene regulation and evolutionary dynamics, including: Replication fidelity. Quality control of gene expression. Genetic diversity of populations and its impact […]
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Developmental and Stem Cell Biology
Developmental biology first made its appearance at Institut Pasteur when François Jacob, François Gros and their colleagues extended their pioneering work on mRNA in bacteria to gene regulation in eukaryotic systems. This led to […]
Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
Nature immunology
Bain CC, Bravo-Blas A, Scott CL, Gomez Perdiguero E, Geissmann F, Henri S, Malissen B, Osborne LC, Artis D, Mowat AMCancer immunology. Identifying the infiltrators
Science (New York, N.Y.)
Gomez Perdiguero E, Geissmann FMyb-independent macrophages: a family of cells that develops with their tissue of residence and is involved in its homeostasis
Cold Spring Harbor symposia on quantitative biology
Gomez Perdiguero E, Geissmann FLymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells
Cell stem cell
Böiers C, Carrelha J, Lutteropp M, Luc S, Green JC, Azzoni E, Woll PS, Mead AJ, Hultquist A, Swiers G, Perdiguero EG, Macaulay IC, Melchiori L, Luis TC, Kharazi S, Bouriez-Jones T, Deng Q, Pontén A, Atkinson D, Jensen CT, Sitnicka E, Geissmann F, Godin I, Sandberg R, de Bruijn MF, Jacobsen SEMicroglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
Nature neuroscience
Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, Wieghofer P, Heinrich A, Riemke P, Hölscher C, Müller DN, Luckow B, Brocker T, Debowski K, Fritz G, Opdenakker G, Diefenbach A, Biber K, Heikenwalder M, Geissmann F, Rosenbauer F, Prinz MDevelopment and homeostasis of “resident” myeloid cells: the case of the microglia
Glia
Gomez Perdiguero E, Schulz C, Geissmann FA lineage of myeloid cells independent of Myb and hematopoietic stem cells
Science (New York, N.Y.)
Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, Prinz M, Wu B, Jacobsen SE, Pollard JW, Frampton J, Liu KJ, Geissmann F![](https://research.pasteur.fr/wp-content/uploads/2016/10/research_pasteur-diagmicoll-volontaire-icareb-150x150.png)