“Functional CURE under some ENIGMATIC mechanisms: Choke-and-Mute, rather than Shoot-and-Kill ?” by Jacques Leibowitch – VIROLOGY DEPARTMENT SEMINAR
HIV signature on RIG-I-like receptors
The pathogenesis of HIV infection, and in particular the development of immunodeficiency, remains incompletely understood. During HIV infection both innate and adaptive immune responses are raised, but they appear to be insufficient or too […]
REEMFOAMY : Human infection with zoonotic simian foamy retroviruses: role of virological and immunological factors in restricting viral emergence
The public health relevance of retroviruses of zoonotic origin is illustrated by the human immunodeficiency virus (HIV) epidemic, the worldwide distribution of human T-lymphotropic viruses (HTLVs), and the morbidity and mortality associated with both […]
Mechanisms of HIV-1 replication and interaction with the immune system. More than 35 years after its appearance, the HIV/AIDS epidemic represents more than ever a public health threat worldwide. About 37 million people are […]
An unprecedented epidemic of Chikungunya virus (CHIKV) infection recently occurred in countries of the Indian Ocean area, causing an acute and painful syndrome with strong fever, asthenia, skin rash, polyarthritis, and lethal cases […]
2018A human immune system mouse model with robust lymph node development, Nat. Methods 2018 Aug;15(8):623-630.
2017More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins, Retrovirology 2017 Nov;14(1):53.
2017HIV Fusion in Dendritic Cells Occurs Mainly at the Surface and Is Limited by Low CD4 Levels, J. Virol. 2017 Nov;91(21).
2017IFITM3 requires an amphipathic helix for antiviral activity, EMBO Rep. 2017 Aug;.
2017HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response, Mol. Cell 2017 Jul;.
2017Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells, EMBO J. 2017 Jun;36(12):1653-1668.
2017CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses, Nature 2017 Mar;543(7646):564-567.
2017Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents, J. Virol. 2017 03;91(6).
2017Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity, Immunity 2017 Feb;46(2):301-314.
2017Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement, Nat Commun 2017 Feb;8:14253.
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