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© Giulia Manina, Institut Pasteur
Mycobacterium tuberculosis dual fluorescent reporter of metabolic activity. Green (active bacilli) and red fluorescence (quiescent bacilli) are merged, 100X magnification.

Events

Microfluidic Large-Scale Integration Applied to Molecular Diagnostics. Prof. Sebastian MAERKL (EPFL)

Building: François Jacob – Room: Auditorium François Jacob – Address: 28 Rue du Dr Roux, Paris, France
2016-11-10 10:30:00 2016-11-10 00:00:00 Europe/London Microfluidic Large-Scale Integration Applied to Molecular Diagnostics. Prof. Sebastian MAERKL (EPFL) We have developed microfluidic devices for high-throughput quantitative studies of protein interactions. In order to enable the measurement of transient molecular interactions we invented a novel detection mechanism based on mechanically induced trapping of […] 28 Rue du Dr Roux, Paris, France

Microfluidics Club at Pasteur Third Seminar: Dr. Gilgueng HWANG

Building: Metchnikoff – 67 – Room: Jules Bordet – Address: Institut Pasteur, 25 Rue du Docteur Roux, Paris, France
2017-03-30 17:30:00 2017-03-30 19:00:00 Europe/London Microfluidics Club at Pasteur Third Seminar: Dr. Gilgueng HWANG Microfluidics Club @ Pasteur Third Seminar Dr. Gilgueng HWANG Centre for Nanoscience and Nanotechnology CNRS                                           […] Institut Pasteur, 25 Rue du Docteur Roux, Paris, France

Projects

CV

Giulia Manina received her Master Degree (2005) and PhD in Genetic and Biomolecular Sciences (2009) from the University of Pavia, Italy. During her PhD studies, as part of a large EU Consortium, New Medicines for Tuberculosis (NM4TB), she worked towards the identification and characterization of the cellular target and resistance mechanism of benzothiazinones, a novel class of antimycobacterial drugs, which has now progressed to the pre-clinical stage. She was awarded the Novartis Prize in 2009 for the best publication on Microbial Pathogens (http://f1000.com/prime/1159796).

Giulia gained structural biology experience during her first short postdoctoral stint at the Institut Pasteur, Paris in 2009, where she performed the structural characterization of the enzyme responsible for benzothiazinones resistance.

She subsequently moved to the Swiss Federal Institute of Technology in Lausanne, Switzerland as a postdoctoral research fellow in the laboratory of Prof. John McKinney, where she has focused on the study of mycobacterial phenotypic heterogeneity, using fluorescent reporters in conjunction with time-lapse microfluidic microscopy. Giulia was awarded the Swiss TB Award 2015 from the Swiss Foundation for Tuberculosis Research, for her single-cell studies on Mycobacterium tuberculosis and for the identification of Non-Growing but Metabolically Active bacilli (NGMA) during infection (doi:10.1016/j.chom.2014.11.016).

Since May 2015 Giulia heads a 5-years junior group ‘Microbial Individuality and Infection’ as a part of the Department of Cell Biology and Infection at the Institut Pasteur in Paris, within the Laboratory of Excellence Integrative Biology of Emerging Infectious Diseases Framework (LabEx IBEID).

Giulia has also received the Qualification to Direct Research (HDR) from the University Paris Descartes (V) in January 2017.

Publications