Dr. Christophe d’Enfert is a Professor at Institut Pasteur and the Head of the Fungal Biology and Pathogenicity Unit at Institut Pasteur. Dr. d’Enfert gained his PhD at Institut Pasteur working on protein secretion in Gram-negative bacteria. During his post-doctoral training at the University of California at Berkeley, he studied protein secretion in yeast. Since 1992, he joined Institut Pasteur to study human pathogenic fungi and has developed both fundamental and applied research on two major fungal pathogens, Candida albicans and Aspergillus fumigatus. Current research in his laboratory focuses on the development of tools for functional genomics of C. albicans and the study of C. albicans genome dynamics and diversity, biofilm formation and morphogenesis.
Christophe d’Enfert is also Scientific Director of Institut Pasteur. He joined Institut Pasteur management in March 2018 as Vice President for Technology and Scientific Programs, in charge of the running and development of core facilities, large infrastructure programs and the implementation of incentive programs. In January 2020, he was appointed Scientific Director of Institut Pasteur, coordinating scientific and medical activities, scientific evaluation and recruitments, access to technology, and teaching.
Dr. d’Enfert was the Vice-Chair of Institut Pasteur Genomes and Genetics Department from 2009 to 2014 and the founding Chair of Institut Pasteur Department of Mycology from 2014 to 2018. He was also a Visiting Professor at Ecole Polytechnique in France from 2004 to 2016 and Scientific Director per interim of the French Technology Research Institute BIOASTER.
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2024Metabolic reprogramming during Candida albicans planktonic-biofilm transition is modulated by the transcription factors Zcf15 and Zcf26., PLoS Biol 2024 Jun; 22(6): e3002693.
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2024A gain-of-function mutation in zinc cluster transcription factor Rob1 Drives Candida albicans adaptive growth in the cystic fibrosis lung environment., PLoS Pathog 2024 Apr; 20(4): e1012154.
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2023Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response., Gut Microbes 2023 Dec; 15(2): 2287618.
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2023The pathogenic and colonization potential of Candida africana., Microbes Infect 2023 Sep; (): 105230.
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2023The Pga59 cell wall protein is an amyloid forming protein involved in adhesion and biofilm establishment in the pathogenic yeast Candida albicans., NPJ Biofilms Microbiomes 2023 Jan; 9(1): 6.
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2022Bending stiffness of Candida albicans hyphae as a proxy of cell wall properties., Lab Chip 2022 Sep; (): .
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2022A phylogenetically-restricted essential cell cycle progression factor in the human pathogen Candida albicans., Nat Commun 2022 Jul; 13(1): 4256.
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2022Spatiotemporal dynamics of calcium signals during neutrophil cluster formation., Proc Natl Acad Sci U S A 2022 Jul; 119(29): e2203855119.
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2022A protocol for ultrastructural study of Candida albicans biofilm using transmission electron microscopy., STAR Protoc 2022 Jul; 3(3): 101514.
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2022Multiple Stochastic Parameters Influence Genome Dynamics in a Heterozygous Diploid Eukaryotic Model., J Fungi (Basel) 2022 Jun; 8(7): .
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