Timeline

Célia Caillet-Saguy

Permanent Researcher

03 Oct 2024

course

Cours Pasteur Structure et fonction des protéines

01 Jan 2024

publication

A short sequence in the tail of SARS-CoV-2 envelope protein controls accessibility of its PDZ-binding motif to the cytoplasm.

01 Jan 2023

publication

Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity.

28 Oct 2022

project

Hijacking of host PDZ proteins during hepatitis B virus infection

01 Jan 2022

publication

Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins.

01 Jan 2022

publication

Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7.

15 Nov 2021

publication

PDZ-Containing Proteins Targeted by the ACE2 Receptor.

30 Sep 2021

course

Biochimie des Protéines

19 Jul 2021

project

Myosins-Usher2 proteins complexes in hearing loss

17 Apr 2021

publication

Host PDZ-containing proteins targeted by SARS-Cov-2.

05 Feb 2021

publication

Role of PDZ-binding motif from West Nile virus NS5 protein on viral replication.

13 Jan 2021

publication

Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein.

01 Jan 2021

publication

PDZ Sample Quality Assessment by Biochemical and Biophysical Characterizations.

06 Nov 2020

publication

Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.

13 Oct 2020

course

Biochimie des Protéines

16 Jul 2020

project

Identification of cellular PDZ-containing Proteins targeted by the virus SARS-Cov-2 during infection (PPCOVi)

07 Jul 2020

publication

Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.

01 Jan 2020

publication

Interactomic affinity profiling by holdup assay: Acetylation and distal residues impact the PDZome-binding specificity of PTEN phosphatase.

01 Oct 2019

publication

Identification of protein-protein and ribonucleoprotein complexes containing Hfq.

15 May 2019

publication

Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein.

08 Feb 2018

project

Mutations in PDZ Binding Motif (PBM)-containing proteins associated to the Usher syndrome

11 Aug 2017

publication

Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains.

31 May 2016

publication

Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ.

11 May 2015

team

Humoral Immunology

05 Mar 2015

publication

Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus.

30 Sep 2014

publication

Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain.

19 Feb 2014

publication

Polymerases of hepatitis C viruses and flaviviruses: structural and mechanistic insights and drug development.

14 Jun 2012

publication

Role of the iron axial ligands of heme carrier HasA in heme uptake and release.

24 Apr 2012

publication

Two crucial early steps in RNA synthesis by the hepatitis C virus polymerase involve a dual role of residue 405

08 Oct 2011

publication

An objective assessment of conformational variability in complexes of hepatitis C virus polymerase with non-nucleoside inhibitors

01 Oct 2011

publication

Human leukocyte antigen B27 selects for rare escape mutations that significantly impair hepatitis C virus replication and require compensatory mutations

05 Jan 2011

publication

A comprehensive structure-function comparison of hepatitis C virus strain JFH1 and J6 polymerases reveals a key residue stimulating replication in cell culture across genotypes

11 Feb 2009

publication

Mapping the interaction between the hemophore HasA and its outer membrane receptor HasR using CRINEPT-TROSY NMR spectroscopy.

19 Jan 2008

publication

Novel heme ligand displacement by CO in the soluble hemophore HasA and its proximal ligand mutants: implications for heme uptake and release

27 Dec 2007

publication

Deciphering the structural role of histidine 83 for heme binding in hemophore HasA.

11 Jan 2006

publication

A little guide for advanced search:

Timeline

Cours Pasteur Structure et fonction des protéines

A short sequence in the tail of SARS-CoV-2 envelope protein controls accessibility of its PDZ-binding motif to the cytoplasm.

Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity.

Hijacking of host PDZ proteins during hepatitis B virus infection

Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins.

Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7.

PDZ-Containing Proteins Targeted by the ACE2 Receptor.

Biochimie des Protéines

Myosins-Usher2 proteins complexes in hearing loss

Host PDZ-containing proteins targeted by SARS-Cov-2.

Role of PDZ-binding motif from West Nile virus NS5 protein on viral replication.

Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein.

PDZ Sample Quality Assessment by Biochemical and Biophysical Characterizations.

Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.

Biochimie des Protéines

Identification of cellular PDZ-containing Proteins targeted by the virus SARS-Cov-2 during infection (PPCOVi)

Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.

Interactomic affinity profiling by holdup assay: Acetylation and distal residues impact the PDZome-binding specificity of PTEN phosphatase.

Identification of protein-protein and ribonucleoprotein complexes containing Hfq.

Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein.

Mutations in PDZ Binding Motif (PBM)-containing proteins associated to the Usher syndrome

Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains.

Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ.

Humoral Immunology

Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus.

Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain.

Polymerases of hepatitis C viruses and flaviviruses: structural and mechanistic insights and drug development.

Role of the iron axial ligands of heme carrier HasA in heme uptake and release.

Two crucial early steps in RNA synthesis by the hepatitis C virus polymerase involve a dual role of residue 405

An objective assessment of conformational variability in complexes of hepatitis C virus polymerase with non-nucleoside inhibitors

Human leukocyte antigen B27 selects for rare escape mutations that significantly impair hepatitis C virus replication and require compensatory mutations

A comprehensive structure-function comparison of hepatitis C virus strain JFH1 and J6 polymerases reveals a key residue stimulating replication in cell culture across genotypes

Mapping the interaction between the hemophore HasA and its outer membrane receptor HasR using CRINEPT-TROSY NMR spectroscopy.

Novel heme ligand displacement by CO in the soluble hemophore HasA and its proximal ligand mutants: implications for heme uptake and release

Deciphering the structural role of histidine 83 for heme binding in hemophore HasA.

Direct-detected 13C NMR to investigate the iron(III) hemophore HasA.