Timeline

Florence Cordier
Permanent Researcher
02 Feb 2023
publication

Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system.

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01 Feb 2023
news

Bacterial pathogenicity: improving understanding of an essential process – molecule secretion

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16 Mar 2022
event

Half-day Latest innovations and Applications in CryoEM& CryoET

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01 Jan 2022
publication

Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7.

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01 Oct 2021
publication

1 H, 15 N and 13 C resonance assignments of the C-terminal domain of PulL, a component of the Klebsiella oxytoca type II secretion system

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06 Nov 2020
publication

Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.

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18 Aug 2020
publication

Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate.

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17 Oct 2019
event

Department of Structural Biology and Chemisry seminar: Xavier Morelli, Integrated strategy for hit-to-lead optimization: the (Cova)DOTS approach (‘Diversity Oriented Target-focused Synthesis’)

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23 May 2019
publication

Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches

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26 Jan 2019
event

11th Conference “NMR: a tool for Biology”, 28-30 Jan 2019

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05 Sep 2018
publication

Structural plasticity of the HHD2 domain of whirlin.

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28 Jun 2018
team

Biological NMR and HDX-MS Technological Platform

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09 Mar 2018
publication

Tuning interval Branch-and-Prune for protein structure determination

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08 Feb 2018
project

Mutations in PDZ Binding Motif (PBM)-containing proteins associated to the Usher syndrome

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28 Sep 2017
publication

Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem

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01 Aug 2017
publication

Conformational switch of harmonin, a submembrane scaffold protein of the hair cell mechanoelectrical transduction machinery

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09 Jul 2016
publication

(1)H, (13)C and (15)N backbone resonance assignments and dynamic properties of the PDZ tandem of Whirlin

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31 May 2016
publication

Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ.

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09 Sep 2015
tool

Nuclear Magnetic Resonance spectrometers

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16 Jul 2015
team

Signalling and Molecular interactions

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07 Jul 2015
project

Bacterial Transmembrane Signaling

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11 May 2015
team

Structural Bioinformatics

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05 May 2015
publication

Deciphering the unconventional peptide binding to the PDZ domain of MAST2

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05 Mar 2015
publication

Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus.

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18 Oct 2014
publication

Quantitative and dynamic analysis of PTEN phosphorylation by NMR

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30 Sep 2014
publication

Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain.

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07 Dec 2012
publication

Ordered phosphorylation events in two independent cascades of the PTEN C-tail revealed by NMR

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14 Aug 2012
publication

Interference with the PTEN-MAST2 interaction by a viral protein leads to cellular relocalization of PTEN

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12 Oct 2011
publication

Peptides targeting the PDZ domain of PTPN4 are efficient inducers of glioblastoma cell death

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29 Aug 2011
publication

Pharmacological and structural characterization of long-sarafotoxins, a new family of endothelin-like peptides: Role of the C-terminus extension

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19 Jan 2010
publication

Attenuation of rabies virulence: takeover by the cytoplasmic domain of its envelope protein

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23 Oct 2009
publication

DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding

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25 Nov 2008
publication

The zinc finger of NEMO is a functional ubiquitin-binding domain

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30 Jan 2008
publication

Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation

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01 Jan 2008
publication

Direct detection of N-H[…]O=C hydrogen bonds in biomolecules by NMR spectroscopy

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01 Jan 2008
publication

Direct detection of N-H[…]N hydrogen bonds in biomolecules by NMR spectroscopy

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07 Jul 2006
publication

DNA recognition by the brinker repressor–an extreme case of coupling between binding and folding

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01 Aug 2005
publication

Nuclear magnetic resonance as a quantitative tool to study interactions in biomacromolecules

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17 Dec 2004
publication

Insights into biomolecular hydrogen bonds from hydrogen bond scalar couplings

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01 Sep 2004
publication

Quantitative comparison of the hydrogen bond network of A-state and native ubiquitin by hydrogen bond scalar couplings

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01 Jul 2004
publication

Quantification of H/D isotope effects on protein hydrogen-bonds by h3JNC’ and 1JNC’ couplings and peptide group 15N and 13C’ chemical shifts

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24 Dec 2003
publication

Direct observation of Calpha-Halpha…O=C hydrogen bonds in proteins by interresidue h3JCalphaC’ scalar couplings

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12 Apr 2002
publication

Temperature-dependence of protein hydrogen bond properties as studied by high-resolution NMR

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01 Jan 2001
publication

An introduction to hydrogen bond scalar couplings

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01 Jan 2001
publication

Scalar couplings across hydrogen bonds

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01 Dec 2000
publication

Ligand-induced strain in hydrogen bonds of the c-Src SH3 domain detected by NMR

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15 Mar 2000
publication

Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain

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01 Oct 1999
publication

Observation of through-hydrogen-bond 2hJHC’ in a perdeuterated protein

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01 Jun 1999
publication

Measurement of 3hJNC’ connectivities across hydrogen bonds in a 30 kDa protein

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17 Mar 1999
publication

Purple membrane induced alignment of biological macromolecules in the magnetic field

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24 Feb 1999
publication

Direct observation of hydrogen bonds in proteins by interresidue (3h)J(NC ‘) scalar couplings

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01 Feb 1999
publication

A doublet-separated sensitivity-enhanced HSQC for the determination of scalar and dipolar one-bond J-couplings

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14 Aug 1998
publication

Solution structure, rotational diffusion anisotropy and local backbone dynamics of Rhodobacter capsulatus cytochrome c2

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13 May 1998
publication

Precision and uncertainty in the characterization of anisotropic rotational diffusion by N-15 relaxation

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01 Mar 1996
publication

Measurement of (13)C (α)- (13)CO cross-relaxation rates in (15)N-/ (13)C-labelled proteins

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01 Nov 1995
publication

Determination of an initial set of NOE-derived distance constraints for the structure determination of N-15/C-13-labeled proteins

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01 Feb 1995
publication

High-resolution 3D HNCOCA experiment applied to a 28 kDa paramagnetic protein

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