Timeline
Florence Cordier
Permanent Researcher
02 Feb 2023
publication
Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system.
Read more01 Feb 2023
news
Bacterial pathogenicity: improving understanding of an essential process – molecule secretion
Read more16 Mar 2022
01 Jan 2022
publication
Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7.
Read more01 Oct 2021
publication
1 H, 15 N and 13 C resonance assignments of the C-terminal domain of PulL, a component of the Klebsiella oxytoca type II secretion system
Read more06 Nov 2020
publication
Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
Read more18 Aug 2020
publication
Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate.
Read more17 Oct 2019
event
Department of Structural Biology and Chemisry seminar: Xavier Morelli, Integrated strategy for hit-to-lead optimization: the (Cova)DOTS approach (‘Diversity Oriented Target-focused Synthesis’)
Read more23 May 2019
publication
Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches
Read more26 Jan 2019
05 Sep 2018
28 Jun 2018
09 Mar 2018
08 Feb 2018
project
Mutations in PDZ Binding Motif (PBM)-containing proteins associated to the Usher syndrome
Read more28 Sep 2017
publication
Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem
Read more01 Aug 2017
publication
Conformational switch of harmonin, a submembrane scaffold protein of the hair cell mechanoelectrical transduction machinery
Read more09 Jul 2016
publication
(1)H, (13)C and (15)N backbone resonance assignments and dynamic properties of the PDZ tandem of Whirlin
Read more31 May 2016
publication
Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ.
Read more09 Sep 2015
16 Jul 2015
07 Jul 2015
11 May 2015
05 May 2015
05 Mar 2015
publication
Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus.
Read more18 Oct 2014
30 Sep 2014
publication
Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain.
Read more07 Dec 2012
publication
Ordered phosphorylation events in two independent cascades of the PTEN C-tail revealed by NMR
Read more14 Aug 2012
publication
Interference with the PTEN-MAST2 interaction by a viral protein leads to cellular relocalization of PTEN
Read more12 Oct 2011
publication
Peptides targeting the PDZ domain of PTPN4 are efficient inducers of glioblastoma cell death
Read more29 Aug 2011
publication
Pharmacological and structural characterization of long-sarafotoxins, a new family of endothelin-like peptides: Role of the C-terminus extension
Read more19 Jan 2010
publication
Attenuation of rabies virulence: takeover by the cytoplasmic domain of its envelope protein
Read more23 Oct 2009
publication
DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding
Read more25 Nov 2008
30 Jan 2008
publication
Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation
Read more01 Jan 2008
publication
Direct detection of N-H[…]O=C hydrogen bonds in biomolecules by NMR spectroscopy
Read more01 Jan 2008
publication
Direct detection of N-H[…]N hydrogen bonds in biomolecules by NMR spectroscopy
Read more07 Jul 2006
publication
DNA recognition by the brinker repressor–an extreme case of coupling between binding and folding
Read more01 Aug 2005
publication
Nuclear magnetic resonance as a quantitative tool to study interactions in biomacromolecules
Read more17 Dec 2004
01 Sep 2004
publication
Quantitative comparison of the hydrogen bond network of A-state and native ubiquitin by hydrogen bond scalar couplings
Read more01 Jul 2004
publication
Quantification of H/D isotope effects on protein hydrogen-bonds by h3JNC’ and 1JNC’ couplings and peptide group 15N and 13C’ chemical shifts
Read more24 Dec 2003
publication
Direct observation of Calpha-Halpha…O=C hydrogen bonds in proteins by interresidue h3JCalphaC’ scalar couplings
Read more12 Apr 2002
publication
Temperature-dependence of protein hydrogen bond properties as studied by high-resolution NMR
Read more01 Jan 2001
01 Jan 2001
01 Dec 2000
publication
Ligand-induced strain in hydrogen bonds of the c-Src SH3 domain detected by NMR
Read more15 Mar 2000
publication
Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain
Read more01 Oct 1999
01 Jun 1999
publication
Measurement of 3hJNC’ connectivities across hydrogen bonds in a 30 kDa protein
Read more17 Mar 1999
publication
Purple membrane induced alignment of biological macromolecules in the magnetic field
Read more24 Feb 1999
publication
Direct observation of hydrogen bonds in proteins by interresidue (3h)J(NC ‘) scalar couplings
Read more01 Feb 1999
publication
A doublet-separated sensitivity-enhanced HSQC for the determination of scalar and dipolar one-bond J-couplings
Read more14 Aug 1998
publication
Solution structure, rotational diffusion anisotropy and local backbone dynamics of Rhodobacter capsulatus cytochrome c2
Read more13 May 1998
publication
Precision and uncertainty in the characterization of anisotropic rotational diffusion by N-15 relaxation
Read more01 Mar 1996
publication
Measurement of (13)C (α)- (13)CO cross-relaxation rates in (15)N-/ (13)C-labelled proteins
Read more01 Nov 1995
publication
Determination of an initial set of NOE-derived distance constraints for the structure determination of N-15/C-13-labeled proteins
Read more01 Feb 1995