Ligne de temps
Florence Cordier
Chercheur(euse) Permanent(e)
02 févr. 2023
publication
Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system.
Lire plus01 févr. 2023
news
Bacterial pathogenicity: improving understanding of an essential process – molecule secretion
Lire plus16 mars 2022
01 janv. 2022
publication
Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7.
Lire plus01 oct. 2021
publication
1 H, 15 N and 13 C resonance assignments of the C-terminal domain of PulL, a component of the Klebsiella oxytoca type II secretion system
Lire plus06 nov. 2020
publication
Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
Lire plus18 août 2020
publication
Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate.
Lire plus17 oct. 2019
event
Department of Structural Biology and Chemisry seminar: Xavier Morelli, Integrated strategy for hit-to-lead optimization: the (Cova)DOTS approach (‘Diversity Oriented Target-focused Synthesis’)
Lire plus23 mai 2019
publication
Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches
Lire plus26 janv. 2019
05 sept. 2018
28 juin 2018
09 mars 2018
08 févr. 2018
project
Mutations in PDZ Binding Motif (PBM)-containing proteins associated to the Usher syndrome
Lire plus28 sept. 2017
publication
Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem
Lire plus01 août 2017
publication
Conformational switch of harmonin, a submembrane scaffold protein of the hair cell mechanoelectrical transduction machinery
Lire plus09 juil. 2016
publication
(1)H, (13)C and (15)N backbone resonance assignments and dynamic properties of the PDZ tandem of Whirlin
Lire plus31 mai 2016
publication
Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ.
Lire plus09 sept. 2015
16 juil. 2015
07 juil. 2015
11 mai 2015
05 mai 2015
05 mars 2015
publication
Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus.
Lire plus18 oct. 2014
30 sept. 2014
publication
Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain.
Lire plus07 déc. 2012
publication
Ordered phosphorylation events in two independent cascades of the PTEN C-tail revealed by NMR
Lire plus14 août 2012
publication
Interference with the PTEN-MAST2 interaction by a viral protein leads to cellular relocalization of PTEN
Lire plus12 oct. 2011
publication
Peptides targeting the PDZ domain of PTPN4 are efficient inducers of glioblastoma cell death
Lire plus29 août 2011
publication
Pharmacological and structural characterization of long-sarafotoxins, a new family of endothelin-like peptides: Role of the C-terminus extension
Lire plus19 janv. 2010
publication
Attenuation of rabies virulence: takeover by the cytoplasmic domain of its envelope protein
Lire plus23 oct. 2009
publication
DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding
Lire plus25 nov. 2008
30 janv. 2008
publication
Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation
Lire plus01 janv. 2008
publication
Direct detection of N-H[…]O=C hydrogen bonds in biomolecules by NMR spectroscopy
Lire plus01 janv. 2008
publication
Direct detection of N-H[…]N hydrogen bonds in biomolecules by NMR spectroscopy
Lire plus07 juil. 2006
publication
DNA recognition by the brinker repressor–an extreme case of coupling between binding and folding
Lire plus01 août 2005
publication
Nuclear magnetic resonance as a quantitative tool to study interactions in biomacromolecules
Lire plus17 déc. 2004
01 sept. 2004
publication
Quantitative comparison of the hydrogen bond network of A-state and native ubiquitin by hydrogen bond scalar couplings
Lire plus01 juil. 2004
publication
Quantification of H/D isotope effects on protein hydrogen-bonds by h3JNC’ and 1JNC’ couplings and peptide group 15N and 13C’ chemical shifts
Lire plus24 déc. 2003
publication
Direct observation of Calpha-Halpha…O=C hydrogen bonds in proteins by interresidue h3JCalphaC’ scalar couplings
Lire plus12 avr. 2002
publication
Temperature-dependence of protein hydrogen bond properties as studied by high-resolution NMR
Lire plus01 janv. 2001
01 janv. 2001
01 déc. 2000
publication
Ligand-induced strain in hydrogen bonds of the c-Src SH3 domain detected by NMR
Lire plus15 mars 2000
publication
Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain
Lire plus01 oct. 1999
01 juin 1999
publication
Measurement of 3hJNC’ connectivities across hydrogen bonds in a 30 kDa protein
Lire plus17 mars 1999
publication
Purple membrane induced alignment of biological macromolecules in the magnetic field
Lire plus24 févr. 1999
publication
Direct observation of hydrogen bonds in proteins by interresidue (3h)J(NC ‘) scalar couplings
Lire plus01 févr. 1999
publication
A doublet-separated sensitivity-enhanced HSQC for the determination of scalar and dipolar one-bond J-couplings
Lire plus14 août 1998
publication
Solution structure, rotational diffusion anisotropy and local backbone dynamics of Rhodobacter capsulatus cytochrome c2
Lire plus13 mai 1998
publication
Precision and uncertainty in the characterization of anisotropic rotational diffusion by N-15 relaxation
Lire plus01 mars 1996
publication
Measurement of (13)C (α)- (13)CO cross-relaxation rates in (15)N-/ (13)C-labelled proteins
Lire plus01 nov. 1995
publication
Determination of an initial set of NOE-derived distance constraints for the structure determination of N-15/C-13-labeled proteins
Lire plus01 févr. 1995