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Présentation
Cours
HIV Science MOOC
In this MOOC we will review different aspects of HIV infection: from its biological origin and its identification as the causative agent of AIDS to the perspectives of eradication. Register on: https://www.fun-mooc.fr/en/courses/hiv-science/ Flyer: MOOC_VIH_2022 […]
2022-03-15 09:00:00
2022-05-10 22:00:00
Europe/Paris
HIV Science MOOC
In this MOOC we will review different aspects of HIV infection: from its biological origin and its identification as the causative agent of AIDS to the perspectives of eradication. Register on: https://www.fun-mooc.fr/en/courses/hiv-science/ Flyer: MOOC_VIH_2022 […]
Projets
CV
RESEARCH POSITIONS
2018-present | Associate Professor and Team Leader in the Unité HIV inflammation et persistance, Institut Pasteur, Paris, France. |
2014-2017 | Assistant Professor and Team Leader in the Unité HIV inflammation et persistance, Institut Pasteur, Paris, France. |
2010-2014 | Assistant Professor in the Unité de Régulation des Infections Rétrovirales, Institut Pasteur, Paris, France. |
2007-2009 | Senior Scientist in the Unité de Régulation des Infections Rétrovirales, Institut Pasteur, Paris, France. |
2003-2007 | Postdoctoral position in the Unité de Régulation des Infections Rétrovirales, Institut Pasteur, Paris, France. Research advisor: Dr. Gianfranco Pancino. Project: Mechanism of resistance to HIV-1 infection in human primary cells. |
2002-2003 | Postdoctoral position in the Division of Viral Products, Center for Biologics Evaluation and Research (CBER), U.S. Food and Drug Administration (FDA), Bethesda MD, USA. Research advisor: Dr. Carol D. Weiss. Project: Rational approaches to block HIV entry. |
1998-2001 | PhD student in the Unidad de Biofisica (CSIC-UPV/EHU), Department of Biochemistry, University of the Basque Country, Leioa, Spain. Research advisor: Prof. J.L. Nieva. Project: Mechanisms of virus-induced membrane fusion. |
1995-1998 | Undergraduate Student in the Unidad de Biofísica (CSIC-UPV/EHU), University of the Basque Country, Leioa, Spain. Research advisors: Prof. A. Alonso and Prof. E. A. Rivas. Projects: Effects of lipids in membrane fusion and Effects of surfactants in the different phases of lipids on model membranes. |
ACADEMIC QUALIFICATION
2013 | HDR in Life Sciences, Université Pierre et Marie Curie, Paris VI, Paris, France. |
2001 | PhD in Biochemistry and Molecular Biology, University of the Basque Country, Leioa, Spain. “Membrane interacting domains in virus and prions”. Suma Cum Laude. |
2000 | MSc degree, in Biochemistry. University of the Basque Country, Leioa, Spain. |
1998 | Graduated in Biochemistry, University of the Basque Country, Leioa, Spain. |
SOME ADDITIONAL PROFESSIONAL RESPONSABILITIES
2017-present | President of Scientific and Medical Committee of SIDACTION | ||
2014-present | Coordinator of the ANRS RHIVIERA consortium on HIV remission | ||
2013-present | Coordinator of the ANRS International Post-Treatment Controllers cohort | ||
2013-present | Member of the Scientific and Medical Committee of SIDACTION | ||
2012-present | Member of the Scientific Committee of CO6 ANRS PRIMO cohort | ||
2012-present | Member of Institut Pasteur’s Groupe de Réflexion sur le SIDA (GRS) | ||
2012-present | Member of the Steering Committee of CO21 ANRS CODEX cohort | ||
2011-2017 | Co-president of the ANRS coordinated action AC32 “HIV reservoirs” | ||
2010-2017 | Elected Member of Institut Pasteur’s Virology Department Council |
Publications
Télécharger-
2022Autopsy Study Defines Composition and Dynamics of the HIV-1 Reservoir after Allogeneic Hematopoietic Stem Cell Transplantation with CCR5Δ32/Δ32 Donor Cells., Viruses 2022 09; 14(9): .
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2022NK cell spatial dynamics and IgA responses in gut-associated lymphoid tissues during SIV infections., Commun Biol 2022 Jul; 5(1): 674.
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2022Novel role of UHRF1 in the epigenetic repression of the latent HIV-1., EBioMedicine 2022 Apr; 79(): 103985.
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2022Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers., Nat Commun 2022 Apr; 13(1): 1944.
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2022Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control., J Clin Invest 2022 06; 132(11): .
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2022Expansion of Immature Neutrophils During SIV Infection Is Associated With Their Capacity to Modulate T-Cell Function., Front Immunol 2022 ; 13(): 781356.
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2021Antiretroviral therapy for HIV controllers: Reasons for initiation and outcomes in the French ANRS-CO21 CODEX cohort., EClinicalMedicine 2021 Jul; 37(): 100963.
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2021Ultrasensitive Detection of p24 in Plasma Samples from People with Primary and Chronic HIV-1 Infection., J Virol 2021 06; 95(14): e0001621.
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2021SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity., Nat Commun 2021 02; 12(1): 1282.
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2021Immunometabolism and HIV-1 pathogenesis: food for thought., Nat. Rev. Immunol. 2021 Jan;21(1):5-19.
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