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Projets
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RESEARCH POSITIONS
| 2018-present | Associate Professor and Team Leader in the Unité HIV inflammation et persistance, Institut Pasteur, Paris, France. |
| 2014-2017 | Assistant Professor and Team Leader in the Unité HIV inflammation et persistance, Institut Pasteur, Paris, France. |
| 2010-2014 | Assistant Professor in the Unité de Régulation des Infections Rétrovirales, Institut Pasteur, Paris, France. |
| 2007-2009 | Senior Scientist in the Unité de Régulation des Infections Rétrovirales, Institut Pasteur, Paris, France. |
| 2003-2007 | Postdoctoral position in the Unité de Régulation des Infections Rétrovirales, Institut Pasteur, Paris, France. Research advisor: Dr. Gianfranco Pancino. Project: Mechanism of resistance to HIV-1 infection in human primary cells. |
| 2002-2003 | Postdoctoral position in the Division of Viral Products, Center for Biologics Evaluation and Research (CBER), U.S. Food and Drug Administration (FDA), Bethesda MD, USA. Research advisor: Dr. Carol D. Weiss. Project: Rational approaches to block HIV entry. |
| 1998-2001 | PhD student in the Unidad de Biofisica (CSIC-UPV/EHU), Department of Biochemistry, University of the Basque Country, Leioa, Spain. Research advisor: Prof. J.L. Nieva. Project: Mechanisms of virus-induced membrane fusion. |
| 1995-1998 | Undergraduate Student in the Unidad de Biofísica (CSIC-UPV/EHU), University of the Basque Country, Leioa, Spain. Research advisors: Prof. A. Alonso and Prof. E. A. Rivas. Projects: Effects of lipids in membrane fusion and Effects of surfactants in the different phases of lipids on model membranes. |
ACADEMIC QUALIFICATION
| 2013 | HDR in Life Sciences, Université Pierre et Marie Curie, Paris VI, Paris, France. |
| 2001 | PhD in Biochemistry and Molecular Biology, University of the Basque Country, Leioa, Spain. “Membrane interacting domains in virus and prions”. Suma Cum Laude. |
| 2000 | MSc degree, in Biochemistry. University of the Basque Country, Leioa, Spain. |
| 1998 | Graduated in Biochemistry, University of the Basque Country, Leioa, Spain. |
SOME ADDITIONAL PROFESSIONAL RESPONSABILITIES
| 2017-present | President of Scientific and Medical Committee of SIDACTION | ||
| 2014-present | Coordinator of the ANRS RHIVIERA consortium on HIV remission | ||
| 2013-present | Coordinator of the ANRS International Post-Treatment Controllers cohort | ||
| 2013-present | Member of the Scientific and Medical Committee of SIDACTION | ||
| 2012-present | Member of the Scientific Committee of CO6 ANRS PRIMO cohort | ||
| 2012-present | Member of Institut Pasteur’s Groupe de Réflexion sur le SIDA (GRS) | ||
| 2012-present | Member of the Steering Committee of CO21 ANRS CODEX cohort | ||
| 2011-2017 | Co-president of the ANRS coordinated action AC32 “HIV reservoirs” | ||
| 2010-2017 | Elected Member of Institut Pasteur’s Virology Department Council | ||
Publications
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2021Antiretroviral therapy for HIV controllers: Reasons for initiation and outcomes in the French ANRS-CO21 CODEX cohort., EClinicalMedicine 2021 Jul; 37(): 100963.
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2021Ultrasensitive detection of p24 in plasma samples from people with primary and chronic HIV-1 infection., J Virol 2021 May; (): .
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2021SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity., Nat Commun 2021 02; 12(1): 1282.
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2021CD32+CD4+ T Cells Sharing B Cell Properties Increase With Simian Immunodeficiency Virus Replication in Lymphoid Tissues., Front Immunol 2021 ; 12(): 695148.
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2021Immunometabolism and HIV-1 pathogenesis: food for thought., Nat. Rev. Immunol. 2021 Jan;21(1):5-19.
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2020Optimal Maturation of the SIV-Specific CD8+ T Cell Response after Primary Infection Is Associated with Natural Control of SIV: ANRS SIC Study., Cell Rep 2020 09; 32(12): 108174.
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2020Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments., Cell Rep 2020 Aug; 32(7): 108037.
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2020The genome-wide methylation profile of CD4+ T cells from HIV-infected individuals identifies distinct patterns associated with disease progression., Clin Infect Dis 2020 Jul; (): .
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2020Extremely low viral reservoir in treated chronically HIV-1-infected individuals., EBioMedicine 2020 Jul; 57(): 102830.
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2020Antiapoptotic Clone 11-Derived Peptides Induce In Vitro Death of CD4+ T Cells Susceptible to HIV-1 Infection., J Virol 2020 07; 94(14): .
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