Désolé, cet article est seulement disponible en EN.
Cliquez pour voir le graph
Connexions
Cliquez pour voir la ligne de temps
Ligne de temps
Présentation
Projets Transversaux
Projets
CV
Uwe Maskos is a native Bavarian. He studied Physics and Chemistry. A graduate of New College, Oxford, he carried out his doctoral work with Professor Sir Edwin M. Southern (Lasker 2005), inventor of the ‘Southern Blot’, pursuing a highly original project, creating what was then going to become the first ever ‘DNA chips’. Having finished his DPhil at an early age, he went on to work in Neurobiology, a discipline that had started to captivate his interest already for a while. In Ron McKay’s laboratory, working at the National Institutes of Health (NIH), he developed a method of intra-uterine transplantation of neural stem cells. This was subsequently used to study the integration of cells derived from knock-out (KO) animals, human stem cells, and from differentiated embryonic stem (ES) cells, that he was also able to derive de novo. He was tenured working with Professor Jean-Pierre Changeux developing novel tools to study the neuronal nicotinic acetylcholine receptor (nAChR) in vivo. He is heading a Research Unit at the Institut Pasteur. In 2010 he received the Prix Duquesne.
Publications
Télécharger-
2024Serum autoantibodies against α7-nicotinic receptors in subgroups of patients with bipolar disorder or schizophrenia: clinical features and link with peripheral inflammation, Translational Psychiatry, 2024, 14 (1), pp.146. ⟨10.1038/s41398-024-02853-8⟩.
-
2023An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies., Nat Commun 2023 Sep; 14(1): 5964.
-
2023Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor., Cell Mol Life Sci 2023 May; 80(6): 164.
-
2023Developmental Changes of Human Neural Progenitor Cells Grafted into the Ventricular System and Prefrontal Cortex of Mouse Brain in Utero., Cells 2023 Mar; 12(7): .
-
2023Impact of the gut microbiome on nicotine’s motivational effects and glial cells in the ventral tegmental area in male mice., Neuropsychopharmacology 2023 Mar; (): .
-
2023Functional maturation of human iPSC-derived pyramidal neurons in vivo is dependent on proximity with the host tissue., Front Cell Neurosci 2023 ; 17(): 1259712.
-
2022[Nicotinic acetylcholine receptor and chronic obstructive pulmonary disease]., Med Sci (Paris) ; 38(8-9): 637-639.
-
2022The Nicotinic Receptor Polymorphism rs16969968 Is Associated with Airway Remodeling and Inflammatory Dysregulation in COPD Patients., Cells 2022 Sep; 11(19): .
-
2022Divergent Roles of α5 and β4 Nicotinic Receptor Subunits in Food Reward and Nicotine-induced Weight Loss in Male Mice., Endocrinology 2022 Jul; 163(7): .
-
2022Nicotinic receptors as SARS-CoV-2 spike co-receptors?, Med Hypotheses 2022 Jan; 158(): 110741.
-
+Voir la liste complète de publications