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@asiersc.bsky.social
(March 13, 2025, 11:16 pm)
Présentation
Cours
HIV Science MOOC
In this MOOC we will review different aspects of HIV infection: from its biological origin and its identification as the causative agent of AIDS to the perspectives of eradication. >>Register here<< In this MOOC […]
2023-11-14 09:00:00
2024-01-31 22:00:00
Europe/Paris
HIV Science MOOC
In this MOOC we will review different aspects of HIV infection: from its biological origin and its identification as the causative agent of AIDS to the perspectives of eradication. >>Register here<< In this MOOC […]
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Projets
Anciennes Équipes
CV
RESEARCH POSITIONS
| 2018-present | Associate Professor and Team Leader in the Unité HIV inflammation et persistance, Institut Pasteur, Paris, France. |
| 2014-2017 | Assistant Professor and Team Leader in the Unité HIV inflammation et persistance, Institut Pasteur, Paris, France. |
| 2010-2014 | Assistant Professor in the Unité de Régulation des Infections Rétrovirales, Institut Pasteur, Paris, France. |
| 2007-2009 | Senior Scientist in the Unité de Régulation des Infections Rétrovirales, Institut Pasteur, Paris, France. |
| 2003-2007 | Postdoctoral position in the Unité de Régulation des Infections Rétrovirales, Institut Pasteur, Paris, France. Research advisor: Dr. Gianfranco Pancino. Project: Mechanism of resistance to HIV-1 infection in human primary cells. |
| 2002-2003 | Postdoctoral position in the Division of Viral Products, Center for Biologics Evaluation and Research (CBER), U.S. Food and Drug Administration (FDA), Bethesda MD, USA. Research advisor: Dr. Carol D. Weiss. Project: Rational approaches to block HIV entry. |
| 1998-2001 | PhD student in the Unidad de Biofisica (CSIC-UPV/EHU), Department of Biochemistry, University of the Basque Country, Leioa, Spain. Research advisor: Prof. J.L. Nieva. Project: Mechanisms of virus-induced membrane fusion. |
| 1995-1998 | Undergraduate Student in the Unidad de Biofísica (CSIC-UPV/EHU), University of the Basque Country, Leioa, Spain. Research advisors: Prof. A. Alonso and Prof. E. A. Rivas. Projects: Effects of lipids in membrane fusion and Effects of surfactants in the different phases of lipids on model membranes. |
ACADEMIC QUALIFICATION
| 2013 | HDR in Life Sciences, Université Pierre et Marie Curie, Paris VI, Paris, France. |
| 2001 | PhD in Biochemistry and Molecular Biology, University of the Basque Country, Leioa, Spain. “Membrane interacting domains in virus and prions”. Suma Cum Laude. |
| 2000 | MSc degree, in Biochemistry. University of the Basque Country, Leioa, Spain. |
| 1998 | Graduated in Biochemistry, University of the Basque Country, Leioa, Spain. |
SOME ADDITIONAL PROFESSIONAL RESPONSABILITIES
| 2017-present | President of Scientific and Medical Committee of SIDACTION | ||
| 2014-present | Coordinator of the ANRS RHIVIERA consortium on HIV remission | ||
| 2013-present | Coordinator of the ANRS International Post-Treatment Controllers cohort | ||
| 2013-present | Member of the Scientific and Medical Committee of SIDACTION | ||
| 2012-present | Member of the Scientific Committee of CO6 ANRS PRIMO cohort | ||
| 2012-present | Member of Institut Pasteur’s Groupe de Réflexion sur le SIDA (GRS) | ||
| 2012-present | Member of the Steering Committee of CO21 ANRS CODEX cohort | ||
| 2011-2017 | Co-president of the ANRS coordinated action AC32 “HIV reservoirs” | ||
| 2010-2017 | Elected Member of Institut Pasteur’s Virology Department Council | ||
Publications
Télécharger-
2024Antiviral capacity of the early CD8 T-cell response is predictive of natural control of SIV infection: Learning in vivo dynamics using ex vivo data., PLoS Comput Biol 2024 Sep; 20(9): e1012434.
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2024Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells., Nat Med 2024 Sep; (): .
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2024Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence., Nat Immunol 2024 Jun; (): .
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2024High concentrations of Maraviroc do not alter immunological and metabolic parameters of CD4 T cells., Sci Rep 2024 Jun; 14(1): 13980.
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2024Dynamics of virological and immunological markers of HIV persistence after allogeneic haematopoietic stem-cell transplantation in the IciStem cohort: a prospective observational cohort study., Lancet HIV 2024 Jun; 11(6): e389-e405.
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2024CD8 + T-cell priming is quantitatively but not qualitatively impaired in people with HIV-1 on antiretroviral therapy., AIDS 2024 Feb; 38(2): 161-166.
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2024Early antiretroviral therapy favors post-treatment SIV control associated with the expansion of enhanced memory CD8+ T-cells., Nat Commun 2024 Jan; 15(1): 178.
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2023[A shot of synTac to activate CD8+ T cells cytotoxic specific response against HIV]., Med Sci (Paris) 2023 Oct; 39(10): 783-786.
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2023Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller., Cell Host Microbe 2023 Jul; (): .
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2023Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infection., EBioMedicine 2023 Apr; 91(): 104557.
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