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MOOC Viruses and Human Cancers
The MOOC offers a broad overview of the state of knowledge on viruses associated with cancer, the different mechanisms of carcinogenesis, the host immune response and progress in preventing tumors. Registration on: https://www.fun-mooc.fr/en/courses/viruses-and-human-cancers/ […]
2021-09-03 09:00:00 2021-10-31 22:00:00 Europe/Paris MOOC Viruses and Human Cancers The MOOC offers a broad overview of the state of knowledge on viruses associated with cancer, the different mechanisms of carcinogenesis, the host immune response and progress in preventing tumors. Registration on: https://www.fun-mooc.fr/en/courses/viruses-and-human-cancers/ […] Institut Pasteur, Rue du Docteur Roux, Paris, France
Alphavirus myopathies and arthritis: modeling and understanding the mechanisms of disease development and persistence
Valérie Choumet (PI)
Arthropod-borne alphaviruses are distributed worldwide and cause considerable human morbidity and mortality. Alphaviruses cause a variety of human diseases, with clinical signs varying from fever or rash to significant inflammatory pathologies including encephalitis (e.g. […]
Interactions between Human T lymphotropic virus type 1 (HTLV-1) and the blood-brain barrier
Philippe Afonso (PI)
Human T-lymphotropic virus type 1 (HTLV-1) is the etiological agent of a slowly progressive neurodegenerative disease, HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). This disease develops upon infiltration of HTLV-1-infected lymphocytes into the central nervous system, […]
2017HTLV-1-induced leukotriene B4 secretion by T cells promotes T cell recruitment and virus propagation., Nat Commun. 2017 Jun 22;8:15890..
2013Productive infection of human skeletal muscle cells by pandemic and seasonal influenza A(H1N1) viruses, PLoS ONE 2013;8(11):e79628.
2013HTLV-1-associated inflammatory myopathies: low proviral load and moderate inflammation in 13 patients from West Indies and West Africa, J. Clin. Virol. 2013 May;57(1):70-6.
2012Transcytosis of HTLV-1 across a tight human epithelial barrier and infection of subepithelial dendritic cells, Blood 2012 Jul;120(3):572-80.
2010Preclinical studies of a modified vaccinia virus Ankara-based HIV candidate vaccine: antigen presentation and antiviral effect, J. Virol. 2010 May;84(10):5314-28.
2008Alteration of blood-brain barrier integrity by retroviral infection, PLoS Pathog. 2008 Nov;4(11):e1000205.
2008Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein, J. Biol. Chem. 2008 Aug;283(32):21899-908.
2007Human blood-brain barrier disruption by retroviral-infected lymphocytes: role of myosin light chain kinase in endothelial tight-junction disorganization, J. Immunol. 2007 Aug;179(4):2576-83.
2007Human muscle satellite cells as targets of Chikungunya virus infection, PLoS ONE 2007;2(6):e527.
2007Characterization of reemerging chikungunya virus, PLoS Pathog. 2007 Jun;3(6):e89.
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