Timeline

Patrick Trieu-Cuot
Head of Structure
04 Apr 2019
publication

Risk Factors for Infant Colonization by Hypervirulent CC17 Group B Streptococcus: Toward the Understanding of Late-onset Disease

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25 Sep 2018
publication

The plasminogen binding protein PbsP is required for brain invasion by hypervirulent CC17 Group B streptococci

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07 Aug 2018
publication

A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection

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21 Jul 2018
publication

The Streptococcus agalactiae cell wall-anchored protein PbsP mediates adhesion to and invasion of epithelial cells by exploiting the host vitronectin/α integrin axis

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16 Apr 2018
publication

Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus

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26 Dec 2017
publication

Colorectal cancer specific conditions promote gut colonization

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20 Nov 2017
publication

Cyclic di-AMP in host-pathogen interactions

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20 Jan 2017
publication

Regulation of PI-2b Pilus Expression in Hypervirulent Streptococcus agalactiae ST-17 BM110

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21 Nov 2016
publication

Changing Epidemiology of Group B Streptococcus Susceptibility to Fluoroquinolones and Aminoglycosides in France

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05 Oct 2016
publication

Environmental fatty acids enable emergence of infectious Staphylococcus aureus resistant to FASII-targeted antimicrobials

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22 Sep 2016
publication

The Pil3 pilus of Streptococcus gallolyticus binds to intestinal mucins and to fibrinogen

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13 Jul 2016
publication

Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production

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08 Apr 2016
event

Journées du Département de Microbiologie

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16 Feb 2016
publication

PbsP, a cell wall-anchored protein that binds plasminogen to promote hematogenous dissemination of group B Streptococcus

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12 Feb 2016
publication

Streptococci Engage TLR13 on Myeloid Cells in a Site-Specific Fashion

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01 Jan 2016
publication

Molecular Characterization of Nonhemolytic and Nonpigmented Group B Streptococci Responsible for Human Invasive Infections

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16 Dec 2015
publication

A Safe and Stable Neonatal Vaccine Targeting GAPDH Confers Protection against Group B Streptococcus Infections in Adult Susceptible Mice

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25 Sep 2015
publication

Evidence for the Sialylation of PilA, the PI-2a Pilus-Associated Adhesin of Streptococcus agalactiae Strain NEM316

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16 Sep 2015
team

Group : Patrick Trieu-Cuot

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17 Jul 2015
publication

Srr2, a multifaceted adhesin expressed by ST-17 hypervirulent Group B Streptococcus involved in binding to both fibrinogen and plasminogen

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02 Jul 2015
project

Biology of Gram positive Pathogens

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05 Jun 2015
publication

Group B streptococcus neonatal invasive infections, France 2007-2012

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30 May 2015
publication

Single nucleotide resolution RNA-seq uncovers new regulatory mechanisms in the opportunistic pathogen Streptococcus agalactiae

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28 May 2015
publication

Multiparametric AFM reveals turgor-responsive net-like peptidoglycan architecture in live streptococci

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26 May 2015
publication

Streptococcus gallolyticus Pil3 Pilus Is Required for Adhesion to Colonic Mucus and for Colonization of Mouse Distal Colon

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11 May 2015
team

Biology of Gram-Positive Pathogens

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28 Jan 2015
publication

Corrigendum: Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline

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31 Oct 2014
publication

Molecular mapping of the cell wall polysaccharides of the human pathogen Streptococcus agalactiae

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27 Oct 2014
publication

Capsular polysaccharide of Group B Streptococcus mediates biofilm formation in the presence of human plasma

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18 Aug 2014
publication

Molecular characterization of Streptococcus agalactiae isolates harboring small erm(T)-carrying plasmids

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04 Aug 2014
publication

Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline

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25 Jul 2014
publication

FbsC, a novel fibrinogen-binding protein, promotes Streptococcus agalactiae-host cell interactions

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05 May 2014
publication

O-Glycosylation of the N-terminal region of the serine-rich adhesin Srr1 of Streptococcus agalactiae explored by mass spectrometry

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01 Apr 2014
publication

RNA and β-hemolysin of group B Streptococcus induce interleukin-1β (IL-1β) by activating NLRP3 inflammasomes in mouse macrophages

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16 Jan 2014
publication

Single cell stochastic regulation of pilus phase variation by an attenuation-like mechanism

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15 Jan 2014
publication

Extracellular nucleotide catabolism by the Group B Streptococcus ectonucleotidase NudP increases bacterial survival in blood

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22 Oct 2013
publication

Construction of isogenic mutants in Streptococcus gallolyticus based on the development of new mobilizable vectors

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27 Sep 2013
publication

TLR2-induced IL-10 production impairs neutrophil recruitment to infected tissues during neonatal bacterial sepsis

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14 Jun 2013
publication

Analysis of the Streptococcus agalactiae exoproteome

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07 Jun 2013
publication

SecA localization and SecA-dependent secretion occurs at new division septa in group B Streptococcus

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02 May 2013
publication

Group B Streptococcus hijacks the host plasminogen system to promote brain endothelial cell invasion

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21 Feb 2013
publication

The Abi-domain protein Abx1 interacts with the CovS histidine kinase to control virulence gene expression in group B Streptococcus

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21 Sep 2012
publication

Capsular switching in group B Streptococcus CC17 hypervirulent clone: a future challenge for polysaccharide vaccine development

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06 Sep 2012
publication

D-alanylation of lipoteichoic acids confers resistance to cationic peptides in group B streptococcus by increasing the cell wall density

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04 Aug 2012
publication

Adult zebrafish model of bacterial meningitis in Streptococcus agalactiae infection

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24 Jul 2012
publication

Epidemiologically and clinically relevant Group B Streptococcus isolates do not bind collagen but display enhanced binding to human fibrinogen

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16 Jul 2012
publication

Molecular basis for different levels of tet(M) expression in Streptococcus pneumoniae clinical isolates

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14 Jun 2012
publication

Role of the Group B antigen of Streptococcus agalactiae: a peptidoglycan-anchored polysaccharide involved in cell wall biogenesis

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20 Mar 2012
publication

Rga, a RofA-like regulator, is the major transcriptional activator of the PI-2a pilus in Streptococcus agalactiae

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23 Jan 2012
publication

Group B streptococcus GAPDH is released upon cell lysis, associates with bacterial surface, and induces apoptosis in murine macrophages

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16 Jan 2012
publication

Activation of the NLRP3 inflammasome by group B streptococci

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27 Dec 2011
publication

Group B Streptococcus surface proteins as major determinants for meningeal tropism

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12 Dec 2011
publication

Effect of PhoP-PhoQ activation by broad repertoire of antimicrobial peptides on bacterial resistance

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01 Dec 2011
publication

An in silico model for identification of small RNAs in whole bacterial genomes: characterization of antisense RNAs in pathogenic Escherichia coli and Streptococcus agalactiae strains

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17 Nov 2011
publication

Inhibition of IL-10 production by maternal antibodies against Group B Streptococcus GAPDH confers immunity to offspring by favoring neutrophil recruitment

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31 Oct 2011
publication

Molecular characterization of a Streptococcus gallolyticus genomic island encoding a pilus involved in endocarditis

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05 Oct 2011
publication

Epidemiology of invasive Streptococcus pyogenes infections in France in 2007

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29 Aug 2011
publication

Invasive group B streptococcal infections in adults, France (2007-2010)

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29 Aug 2011
publication

Invasive group A streptococcal infections in adults, France (2006-2010)

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28 Apr 2011
publication

[A breakthrough in the understanding of neonatal group B streptococcus meningitis]

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15 Apr 2011
publication

The GBS PI-2a pilus is required for virulence in mice neonates

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19 Feb 2011
publication

Comparison of the Diversilab® system with multi-locus sequence typing and pulsed-field gel electrophoresis for the characterization of Streptococcus agalactiae invasive strains

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18 Oct 2010
publication

The surface protein HvgA mediates group B streptococcus hypervirulence and meningeal tropism in neonates

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22 Mar 2010
publication

The 2-Cys peroxiredoxin alkyl hydroperoxide reductase c binds heme and participates in its intracellular availability in Streptococcus agalactiae

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05 Feb 2010
publication

Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis

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27 Jan 2010
publication

Cell surface of Lactococcus lactis is covered by a protective polysaccharide pellicle

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08 May 2009
publication

Dual role for pilus in adherence to epithelial cells and biofilm formation in Streptococcus agalactiae

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24 Apr 2009
publication

Molecular dissection of the secA2 locus of group B Streptococcus reveals that glycosylation of the Srr1 LPXTG protein is required for full virulence

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01 Mar 2009
publication

Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

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18 Dec 2008
publication

Atypical association of DDE transposition with conjugation specifies a new family of mobile elements

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11 Dec 2008
publication

TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA

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02 Oct 2008
publication

Shaping a bacterial genome by large chromosomal replacements, the evolutionary history of Streptococcus agalactiae

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01 Oct 2008
publication

Invasive group B streptococcal infections in infants, France

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01 May 2008
publication

Lipoproteins are critical TLR2 activating toxins in group B streptococcal sepsis

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01 Feb 2008
publication

Fluoroquinolone-resistant group B streptococci in acute exacerbation of chronic bronchitis

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09 Jun 2007
publication

Interaction with human plasminogen system turns on proteolytic activity in Streptococcus agalactiae and enhances its virulence in a mouse model

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17 Apr 2007
publication

Comparative evaluation of VITEK 2 for antimicrobial susceptibility testing of group B Streptococcus

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21 Mar 2007
publication

Multiplex PCR assay for rapid and accurate capsular typing of group B streptococci

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05 Feb 2007
publication

The putative glycosyltransferase-encoding gene cylJ and the group B Streptococcus (GBS)-specific gene cylK modulate hemolysin production and virulence of GBS

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01 Feb 2007
publication

Streptococcus agalactiae GAPDH is a virulence-associated immunomodulatory protein

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25 Sep 2006
publication

The Group B Streptococcus NADH oxidase Nox-2 is involved in fatty acid biosynthesis during aerobic growth and contributes to virulence

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01 Jun 2006
publication

Assembly and role of pili in group B streptococci

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21 Apr 2006
publication

Rapid detection of the “highly virulent” group B Streptococcus ST-17 clone

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01 Apr 2006
publication

Roles of environmental heme, and menaquinone, in streptococcus agalactiae

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19 Jan 2006
publication

Genomic diversity and evolution within the species Streptococcus agalactiae

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01 Jun 2005
publication

The SrtA Sortase of Streptococcus agalactiae is required for cell wall anchoring of proteins containing the LPXTG motif, for adhesion to epithelial cells, and for colonization of the mouse intestine

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01 Jun 2005
publication

Use of genotypic identification by sodA sequencing in a prospective study to examine the distribution of coagulase-negative Staphylococcus species among strains recovered during septic orthopedic surgery and evaluate their significance

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15 May 2005
publication

Role of lipoteichoic acid in the phagocyte response to group B streptococcus

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01 May 2005
publication

Prospective evaluation of a real-time PCR assay for detection of group B streptococci in vaginal swabs from pregnant women

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01 May 2005
publication

Rapid and accurate identification of human isolates of Pasteurella and related species by sequencing the sodA gene

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01 Apr 2005
publication

Respiration metabolism of Group B Streptococcus is activated by environmental haem and quinone and contributes to virulence

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01 Apr 2005
publication

Genetic basis of antibiotic resistance in clinical isolates of Streptococcus gallolyticus (Streptococcus bovis)

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01 Feb 2005
publication

[Why group A streptococci is strictly pathogen in human? A first answer given by a humanized mouse model]

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28 Jan 2005
publication

Sorting sortases: a nomenclature proposal for the various sortases of Gram-positive bacteria

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01 Dec 2004
publication

CovS/CovR of group B streptococcus: a two-component global regulatory system involved in virulence

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01 Oct 2004
publication

Accuracy of phenotypic and genotypic testing for identification of Streptococcus pneumoniae and description of Streptococcus pseudopneumoniae sp. nov

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01 Oct 2004
publication

Use of sodA sequencing for the identification of clinical isolates of coagulase-negative staphylococci

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01 Sep 2003
publication

Attenuated virulence of Streptococcus agalactiae deficient in D-alanyl-lipoteichoic acid is due to an increased susceptibility to defensins and phagocytic cells

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01 Feb 2003
publication

Role of the Streptococcus agalactiae ClpP serine protease in heat-induced stress defence and growth arrest

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01 Feb 2003
publication

Genetic basis of antibiotic resistance in Streptococcus agalactiae strains isolated in a French hospital

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01 Nov 2002
publication

Genetics of streptococci, lactococci, and enterococci: review of the sixth international conference

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01 Sep 2002
publication

Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease

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01 Jul 2002
publication

Taxonomic dissection of the Streptococcus bovis group by analysis of manganese-dependent superoxide dismutase gene (sodA) sequences: reclassification of ‘Streptococcus infantarius subsp. coli’ as Streptococcus lutetiensis sp. nov. and of Streptococcus bovis biotype 11.2 as Streptococcus pasteurianus sp. nov

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01 Jul 2002
publication

Native valve endocarditis due to Enterococcus hirae

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01 Jan 2002
publication

Formation of D-alanyl-lipoteichoic acid is required for adhesion and virulence of Listeria monocytogenes

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01 Dec 2001
publication

Rapid and accurate species-level identification of coagulase-negative staphylococci by using the sodA gene as a target

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01 Nov 2001
publication

Regulation of D-alanyl-lipoteichoic acid biosynthesis in Streptococcus agalactiae involves a novel two-component regulatory system

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15 Sep 2001
publication

Minimizing potential resistance: the molecular view

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01 Aug 2001
publication

Contribution of Mn-cofactored superoxide dismutase (SodA) to the virulence of Streptococcus agalactiae

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01 Apr 2001
publication

Identification of new genes involved in the virulence of Listeria monocytogenes by signature-tagged transposon mutagenesis

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01 Jun 2000
publication

Optimization of green fluorescent protein expression vectors for in vitro and in vivo detection of Listeria monocytogenes

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01 Mar 2000
publication

Characterization of the Tn916-like transposon Tn3872 in a strain of abiotrophia defectiva (Streptococcus defectivus) causing sequential episodes of endocarditis in a child

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01 Jan 2000
publication

Sequencing the gene encoding manganese-dependent superoxide dismutase for rapid species identification of enterococci

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01 Jul 1999
publication

Characterization of IS1541-like elements in Yersinia enterocolitica and Yersinia pseudotuberculosis

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01 Dec 1998
publication

Structural and functional characterization of IS1358 from Vibrio cholerae

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01 Apr 1998
publication

Circularization of Tn916 is required for expression of the transposon-encoded transfer functions: characterization of long tetracycline-inducible transcripts reading through the attachment site

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01 Jan 1998
publication

A novel extended-spectrum TEM-type beta-lactamase (TEM-52) associated with decreased susceptibility to moxalactam in Klebsiella pneumoniae

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01 Jan 1998
publication

Molecular characterization of IS1541 insertions in the genome of Yersinia pestis

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01 Jan 1998
publication

Identification of streptococci to species level by sequencing the gene encoding the manganese-dependent superoxide dismutase

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19 Dec 1997
publication

Molecular characterization and expression analysis of the superoxide dismutase gene from Streptococcus agalactiae

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15 Nov 1997
publication

A broad-host-range mobilizable shuttle vector for the construction of transcriptional fusions to beta-galactosidase in gram-positive bacteria

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01 Apr 1997
publication

Use of an excision reporter plasmid to study the intracellular mobility of the conjugative transposon Tn916 in gram-positive bacteria

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01 Jan 1997
publication

Summary of the round table discussion on genome structure and regulation of gene expression in streptococci and enterococci

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01 Jan 1997
publication

Emergence of vancomycin resistance in the genus Streptococcus: characterization of a vanB transferable determinant in Streptococcus bovis

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01 May 1996
publication

Chromosomal gentamicin resistance transposon Tn3706 in Streptococcus agalactiae B128

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01 Jan 1996
publication

The inlA gene required for cell invasion is conserved and specific to Listeria monocytogenes

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15 Aug 1995
publication

Characterization of superoxide dismutase genes from gram-positive bacteria by polymerase chain reaction using degenerate primers

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01 Feb 1995
publication

Conjugative transposition of Tn916-related elements from Enterococcus faecalis to Escherichia coli and Pseudomonas fluorescens

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15 Sep 1994
publication

Heterogeneric conjugal transfer of the pheromone-responsive plasmid pIP964 (IncHlyI) of Enterococcus faecalis in the apparent absence of pheromone induction

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01 Dec 1993
publication

Study of heterogeneity of chloramphenicol acetyltransferase (CAT) genes in streptococci and enterococci by polymerase chain reaction: characterization of a new CAT determinant

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01 May 1993
publication

Enhanced conjugative transfer of plasmid DNA from Escherichia coli to Staphylococcus aureus and Listeria monocytogenes

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01 Apr 1993
publication

Sequence requirements for target activity in site-specific recombination mediated by the Int protein of transposon Tn 1545

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01 Nov 1992
publication

Nucleotide sequence of the chloramphenicol resistance determinant of the streptococcal plasmid pIP501

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01 Feb 1992
publication

Genetic basis of tetracycline resistance in clinical isolates of Listeria monocytogenes

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01 Feb 1992
publication

Conjugal transfer of plasmid DNA from Enterococcus faecalis to Escherichia coli in digestive tracts of gnotobiotic mice

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30 Sep 1991
publication

An integrative vector exploiting the transposition properties of Tn1545 for insertional mutagenesis and cloning of genes from gram-positive bacteria

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01 Aug 1991
publication

Nucleotide sequences specific for Tn1545-like conjugative transposons in pneumococci and staphylococci resistant to tetracycline

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01 Jul 1991
publication

Conjugative transposition of Tn916 requires the excisive and integrative activities of the transposon-encoded integrase

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15 Jun 1991
publication

Shuttle vectors containing a multiple cloning site and a lacZ alpha gene for conjugal transfer of DNA from Escherichia coli to gram-positive bacteria

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01 Jan 1991
publication

Inducible transfer of conjugative transposon Tn1545 from Enterococcus faecalis to Listeria monocytogenes in the digestive tracts of gnotobiotic mice

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01 Sep 1990
publication

The integration-excision system of the conjugative transposon Tn 1545 is structurally and functionally related to those of lambdoid phages

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25 Jul 1990
publication

A pair of mobilizable shuttle vectors conferring resistance to spectinomycin for molecular cloning in Escherichia coli and in gram-positive bacteria

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25 Jun 1990
publication

Nucleotide sequence of the erythromycin resistance gene of the conjugative transposon Tn1545

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16 Jun 1990
publication

Transferable plasmid-mediated antibiotic resistance in Listeria monocytogenes

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01 Aug 1989
publication

Molecular characterization of two proteins involved in the excision of the conjugative transposon Tn1545: homologies with other site-specific recombinases

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01 Jan 1989
publication

[Current aspects of bacterial resistance to antibiotics]

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01 Sep 1988
publication

Conjugative plasmid transfer from Enterococcus faecalis to Escherichia coli

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01 Jul 1988
publication

Mechanism of action of spiramycin and other macrolides

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01 Sep 1987
publication

Origin, evolution and dissemination of antibiotic resistance genes

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01 May 1987
publication

Nucleotide sequence of the kanamycin resistance determinant of the pneumococcal transposon Tn1545: evolutionary relationships and transcriptional analysis of aphA-3 genes

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01 Oct 1986
publication

Evolution and transfer of aminoglycoside resistance genes under natural conditions

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11 Sep 1986
publication

Nucleotide sequence of the tetM tetracycline resistance determinant of the streptococcal conjugative shuttle transposon Tn1545

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16 Dec 1985
publication

In vivo transfer of genetic information between gram-positive and gram-negative bacteria

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01 Sep 1985
publication

Structural relationship between the genes encoding 3′-aminoglycoside phosphotransferases in Campylobacter and in gram-positive cocci

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01 Jul 1985
publication

Transposition behavior of IS15 and its progenitor IS15-delta: are cointegrates exclusive end products?

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01 Jan 1985
publication

DNA sequences specifying the transcription of the streptococcal kanamycin resistance gene in Escherichia coli and Bacillus subtilis

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01 Oct 1984
publication

Nucleotide sequence of the transposable element IS15

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01 Sep 1983
publication

An IS15 insertion generates an eight-base-pair duplication of the target DNA

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01 Sep 1983
publication

Nucleotide sequence of the Streptococcus faecalis plasmid gene encoding the 3’5″-aminoglycoside phosphotransferase type III

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01 Feb 1982
publication

Purification and characterization of bovine gastricsin

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01 Jan 1982
publication

Study of the heterogeneity of bovine pepsin A by pseudo isoelectric focusing

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