Timeline
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Patrick Trieu-Cuot
Head of Structure
30 Nov 2023
publication
Transcriptome profiling of human col\onic cells exposed to the gut pathobiont Streptococcus gallolyticus subsp. gallolyticus.
Read more23 Mar 2023
publication
Gallocin A, an Atypical Two-Peptide Bacteriocin with Intramolecular Disulfide Bonds Required for Activity.
Read more11 Jan 2023
publication
The c-di-AMP-binding protein CbpB modulates the level of ppGpp alarmone in Streptococcus agalactiae.
Read more10 Nov 2022
11 Mar 2022
publication
Detection of Streptococcus gallolyticus and Four Other CRC- Associated Bacteria in Patient Stools Reveals a Potential “Driver” Role for Enterotoxigenic Bacteroides fragilis
Read more01 Jan 2022
publication
Detection of Streptococcus gallolyticus and Four Other CRC-Associated Bacteria in Patient Stools Reveals a Potential “Driver” Role for Enterotoxigenic Bacteroides fragilis.
Read more01 Sep 2021
publication
The CovR regulatory network drives the evolution of Group B Streptococcus virulence.
Read more30 Aug 2021
publication
Prevalence and Factors Associated with Maternal Group B Streptococcus Colonization in Madagascar and Senegal.
Read more01 Jul 2021
02 Feb 2021
publication
(p)ppGpp/GTP and Malonyl-CoA Modulate Staphylococcus aureus Adaptation to FASII Antibiotics and Provide a Basis for Synergistic Bi-Therapy.
Read more05 Jan 2021
publication
Characterization of a Four-Component Regulatory System Controlling Bacteriocin Production in Streptococcus gallolyticus.
Read more04 Apr 2019
publication
Risk Factors for Infant Colonization by Hypervirulent CC17 Group B Streptococcus: Toward the Understanding of Late-onset Disease
Read more25 Sep 2018
publication
The plasminogen binding protein PbsP is required for brain invasion by hypervirulent CC17 Group B streptococci
Read more07 Aug 2018
publication
A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection
Read more21 Jul 2018
publication
The Streptococcus agalactiae cell wall-anchored protein PbsP mediates adhesion to and invasion of epithelial cells by exploiting the host vitronectin/α integrin axis
Read more16 Apr 2018
publication
Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus
Read more26 Dec 2017
20 Nov 2017
20 Jan 2017
publication
Regulation of PI-2b Pilus Expression in Hypervirulent Streptococcus agalactiae ST-17 BM110
Read more21 Nov 2016
publication
Changing Epidemiology of Group B Streptococcus Susceptibility to Fluoroquinolones and Aminoglycosides in France
Read more05 Oct 2016
publication
Environmental fatty acids enable emergence of infectious Staphylococcus aureus resistant to FASII-targeted antimicrobials
Read more22 Sep 2016
publication
The Pil3 pilus of Streptococcus gallolyticus binds to intestinal mucins and to fibrinogen
Read more13 Jul 2016
publication
Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production
Read more08 Apr 2016
16 Feb 2016
publication
PbsP, a cell wall-anchored protein that binds plasminogen to promote hematogenous dissemination of group B Streptococcus
Read more12 Feb 2016
01 Jan 2016
publication
Molecular Characterization of Nonhemolytic and Nonpigmented Group B Streptococci Responsible for Human Invasive Infections
Read more16 Dec 2015
publication
A Safe and Stable Neonatal Vaccine Targeting GAPDH Confers Protection against Group B Streptococcus Infections in Adult Susceptible Mice
Read more25 Sep 2015
publication
Evidence for the Sialylation of PilA, the PI-2a Pilus-Associated Adhesin of Streptococcus agalactiae Strain NEM316
Read more17 Jul 2015
publication
Srr2, a multifaceted adhesin expressed by ST-17 hypervirulent Group B Streptococcus involved in binding to both fibrinogen and plasminogen
Read more02 Jul 2015
05 Jun 2015
30 May 2015
publication
Single nucleotide resolution RNA-seq uncovers new regulatory mechanisms in the opportunistic pathogen Streptococcus agalactiae
Read more28 May 2015
publication
Multiparametric AFM reveals turgor-responsive net-like peptidoglycan architecture in live streptococci
Read more26 May 2015
publication
Streptococcus gallolyticus Pil3 Pilus Is Required for Adhesion to Colonic Mucus and for Colonization of Mouse Distal Colon
Read more28 Jan 2015
publication
Corrigendum: Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline
Read more31 Oct 2014
publication
Molecular mapping of the cell wall polysaccharides of the human pathogen Streptococcus agalactiae
Read more27 Oct 2014
publication
Capsular polysaccharide of Group B Streptococcus mediates biofilm formation in the presence of human plasma
Read more18 Aug 2014
publication
Molecular characterization of Streptococcus agalactiae isolates harboring small erm(T)-carrying plasmids
Read more04 Aug 2014
publication
Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline.
Read more25 Jul 2014
publication
FbsC, a novel fibrinogen-binding protein, promotes Streptococcus agalactiae-host cell interactions
Read more05 May 2014
publication
O-Glycosylation of the N-terminal region of the serine-rich adhesin Srr1 of Streptococcus agalactiae explored by mass spectrometry
Read more01 Apr 2014
publication
RNA and β-hemolysin of group B Streptococcus induce interleukin-1β (IL-1β) by activating NLRP3 inflammasomes in mouse macrophages
Read more16 Jan 2014
publication
Single cell stochastic regulation of pilus phase variation by an attenuation-like mechanism
Read more15 Jan 2014
publication
Extracellular nucleotide catabolism by the Group B Streptococcus ectonucleotidase NudP increases bacterial survival in blood
Read more22 Oct 2013
publication
Construction of isogenic mutants in Streptococcus gallolyticus based on the development of new mobilizable vectors
Read more27 Sep 2013
publication
TLR2-induced IL-10 production impairs neutrophil recruitment to infected tissues during neonatal bacterial sepsis
Read more14 Jun 2013
07 Jun 2013
publication
SecA localization and SecA-dependent secretion occurs at new division septa in group B Streptococcus
Read more02 May 2013
publication
Group B Streptococcus hijacks the host plasminogen system to promote brain endothelial cell invasion
Read more21 Feb 2013
publication
The Abi-domain protein Abx1 interacts with the CovS histidine kinase to control virulence gene expression in group B Streptococcus
Read more21 Sep 2012
publication
Capsular switching in group B Streptococcus CC17 hypervirulent clone: a future challenge for polysaccharide vaccine development
Read more06 Sep 2012
publication
D-alanylation of lipoteichoic acids confers resistance to cationic peptides in group B streptococcus by increasing the cell wall density
Read more04 Aug 2012
publication
Adult zebrafish model of bacterial meningitis in Streptococcus agalactiae infection
Read more24 Jul 2012
publication
Epidemiologically and clinically relevant Group B Streptococcus isolates do not bind collagen but display enhanced binding to human fibrinogen
Read more16 Jul 2012
publication
Molecular basis for different levels of tet(M) expression in Streptococcus pneumoniae clinical isolates
Read more14 Jun 2012
publication
Role of the Group B antigen of Streptococcus agalactiae: a peptidoglycan-anchored polysaccharide involved in cell wall biogenesis
Read more20 Mar 2012
publication
Rga, a RofA-like regulator, is the major transcriptional activator of the PI-2a pilus in Streptococcus agalactiae
Read more23 Jan 2012
publication
Group B streptococcus GAPDH is released upon cell lysis, associates with bacterial surface, and induces apoptosis in murine macrophages
Read more16 Jan 2012
27 Dec 2011
publication
Group B Streptococcus surface proteins as major determinants for meningeal tropism
Read more12 Dec 2011
publication
Effect of PhoP-PhoQ activation by broad repertoire of antimicrobial peptides on bacterial resistance
Read more01 Dec 2011
publication
An in silico model for identification of small RNAs in whole bacterial genomes: characterization of antisense RNAs in pathogenic Escherichia coli and Streptococcus agalactiae strains
Read more17 Nov 2011
publication
Inhibition of IL-10 production by maternal antibodies against Group B Streptococcus GAPDH confers immunity to offspring by favoring neutrophil recruitment
Read more31 Oct 2011
publication
Molecular characterization of a Streptococcus gallolyticus genomic island encoding a pilus involved in endocarditis
Read more05 Oct 2011
29 Aug 2011
29 Aug 2011
15 Apr 2011
01 Apr 2011
publication
[A breakthrough in the understanding of neonatal group B streptococcus meningitis].
Read more19 Feb 2011
publication
Comparison of the Diversilab® system with multi-locus sequence typing and pulsed-field gel electrophoresis for the characterization of Streptococcus agalactiae invasive strains
Read more22 Mar 2010
publication
The 2-Cys peroxiredoxin alkyl hydroperoxide reductase c binds heme and participates in its intracellular availability in Streptococcus agalactiae
Read more05 Feb 2010
publication
Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis
Read more27 Jan 2010
publication
Cell surface of Lactococcus lactis is covered by a protective polysaccharide pellicle
Read more08 May 2009
publication
Dual role for pilus in adherence to epithelial cells and biofilm formation in Streptococcus agalactiae
Read more24 Apr 2009
publication
Molecular dissection of the secA2 locus of group B Streptococcus reveals that glycosylation of the Srr1 LPXTG protein is required for full virulence
Read more01 Mar 2009
publication
Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens
Read more18 Dec 2008
publication
Atypical association of DDE transposition with conjugation specifies a new family of mobile elements
Read more11 Dec 2008
publication
TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA
Read more02 Oct 2008
publication
Shaping a bacterial genome by large chromosomal replacements, the evolutionary history of Streptococcus agalactiae
Read more01 Oct 2008
01 May 2008
publication
Lipoproteins are critical TLR2 activating toxins in group B streptococcal sepsis
Read more01 Feb 2008
publication
Fluoroquinolone-resistant group B streptococci in acute exacerbation of chronic bronchitis
Read more09 Jun 2007
publication
Interaction with human plasminogen system turns on proteolytic activity in Streptococcus agalactiae and enhances its virulence in a mouse model
Read more17 Apr 2007
publication
Comparative evaluation of VITEK 2 for antimicrobial susceptibility testing of group B Streptococcus
Read more21 Mar 2007
publication
Multiplex PCR assay for rapid and accurate capsular typing of group B streptococci
Read more05 Feb 2007
publication
The putative glycosyltransferase-encoding gene cylJ and the group B Streptococcus (GBS)-specific gene cylK modulate hemolysin production and virulence of GBS
Read more01 Feb 2007
publication
Streptococcus agalactiae GAPDH is a virulence-associated immunomodulatory protein
Read more25 Sep 2006
publication
The Group B Streptococcus NADH oxidase Nox-2 is involved in fatty acid biosynthesis during aerobic growth and contributes to virulence
Read more01 Jun 2006
21 Apr 2006
01 Apr 2006
19 Jan 2006
01 Jun 2005
publication
Use of genotypic identification by sodA sequencing in a prospective study to examine the distribution of coagulase-negative Staphylococcus species among strains recovered during septic orthopedic surgery and evaluate their significance
Read more01 Jun 2005
publication
The SrtA Sortase of Streptococcus agalactiae is required for cell wall anchoring of proteins containing the LPXTG motif, for adhesion to epithelial cells, and for colonization of the mouse intestine
Read more15 May 2005
01 May 2005
publication
Prospective evaluation of a real-time PCR assay for detection of group B streptococci in vaginal swabs from pregnant women
Read more01 May 2005
publication
Rapid and accurate identification of human isolates of Pasteurella and related species by sequencing the sodA gene
Read more01 Apr 2005
publication
Genetic basis of antibiotic resistance in clinical isolates of Streptococcus gallolyticus (Streptococcus bovis)
Read more01 Apr 2005
publication
Respiration metabolism of Group B Streptococcus is activated by environmental haem and quinone and contributes to virulence
Read more01 Feb 2005
publication
[Why group A streptococci is strictly pathogen in human? A first answer given by a humanized mouse model]
Read more28 Jan 2005
publication
Sorting sortases: a nomenclature proposal for the various sortases of Gram-positive bacteria
Read more01 Dec 2004
publication
CovS/CovR of group B streptococcus: a two-component global regulatory system involved in virulence
Read more01 Oct 2004
publication
Accuracy of phenotypic and genotypic testing for identification of Streptococcus pneumoniae and description of Streptococcus pseudopneumoniae sp. nov
Read more01 Oct 2004
publication
Use of sodA sequencing for the identification of clinical isolates of coagulase-negative staphylococci
Read more01 Sep 2003
publication
Attenuated virulence of Streptococcus agalactiae deficient in D-alanyl-lipoteichoic acid is due to an increased susceptibility to defensins and phagocytic cells
Read more01 Feb 2003
publication
Role of the Streptococcus agalactiae ClpP serine protease in heat-induced stress defence and growth arrest
Read more01 Feb 2003
publication
Genetic basis of antibiotic resistance in Streptococcus agalactiae strains isolated in a French hospital
Read more01 Nov 2002
publication
Genetics of streptococci, lactococci, and enterococci: review of the sixth international conference
Read more01 Sep 2002
publication
Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease
Read more01 Jul 2002
publication
Taxonomic dissection of the Streptococcus bovis group by analysis of manganese-dependent superoxide dismutase gene (sodA) sequences: reclassification of ‘Streptococcus infantarius subsp. coli’ as Streptococcus lutetiensis sp. nov. and of Streptococcus bovis biotype 11.2 as Streptococcus pasteurianus sp. nov
Read more01 Jul 2002
01 Jan 2002
publication
Formation of D-alanyl-lipoteichoic acid is required for adhesion and virulence of Listeria monocytogenes
Read more01 Dec 2001
publication
Rapid and accurate species-level identification of coagulase-negative staphylococci by using the sodA gene as a target
Read more01 Nov 2001
publication
Regulation of D-alanyl-lipoteichoic acid biosynthesis in Streptococcus agalactiae involves a novel two-component regulatory system
Read more15 Sep 2001
01 Aug 2001
publication
Contribution of Mn-cofactored superoxide dismutase (SodA) to the virulence of Streptococcus agalactiae
Read more01 Apr 2001
publication
Identification of new genes involved in the virulence of Listeria monocytogenes by signature-tagged transposon mutagenesis
Read more01 Jun 2000
publication
Optimization of green fluorescent protein expression vectors for in vitro and in vivo detection of Listeria monocytogenes
Read more01 Mar 2000
publication
Characterization of the Tn916-like transposon Tn3872 in a strain of abiotrophia defectiva (Streptococcus defectivus) causing sequential episodes of endocarditis in a child
Read more01 Jan 2000
publication
Sequencing the gene encoding manganese-dependent superoxide dismutase for rapid species identification of enterococci
Read more01 Jul 1999
publication
Characterization of IS1541-like elements in Yersinia enterocolitica and Yersinia pseudotuberculosis
Read more01 Dec 1998
01 Apr 1998
publication
Circularization of Tn916 is required for expression of the transposon-encoded transfer functions: characterization of long tetracycline-inducible transcripts reading through the attachment site
Read more01 Jan 1998
publication
Identification of streptococci to species level by sequencing the gene encoding the manganese-dependent superoxide dismutase
Read more01 Jan 1998
publication
A novel extended-spectrum TEM-type beta-lactamase (TEM-52) associated with decreased susceptibility to moxalactam in Klebsiella pneumoniae
Read more01 Jan 1998
publication
Molecular characterization of IS1541 insertions in the genome of Yersinia pestis
Read more19 Dec 1997
publication
Molecular characterization and expression analysis of the superoxide dismutase gene from Streptococcus agalactiae
Read more15 Nov 1997
publication
A broad-host-range mobilizable shuttle vector for the construction of transcriptional fusions to beta-galactosidase in gram-positive bacteria
Read more01 Apr 1997
publication
Use of an excision reporter plasmid to study the intracellular mobility of the conjugative transposon Tn916 in gram-positive bacteria
Read more01 Jan 1997
publication
Summary of the round table discussion on genome structure and regulation of gene expression in streptococci and enterococci
Read more01 Jan 1997
publication
Emergence of vancomycin resistance in the genus Streptococcus: characterization of a vanB transferable determinant in Streptococcus bovis
Read more01 May 1996
publication
Chromosomal gentamicin resistance transposon Tn3706 in Streptococcus agalactiae B128
Read more01 Jan 1996
publication
The inlA gene required for cell invasion is conserved and specific to Listeria monocytogenes
Read more15 Aug 1995
publication
Characterization of superoxide dismutase genes from gram-positive bacteria by polymerase chain reaction using degenerate primers
Read more01 Feb 1995
publication
Conjugative transposition of Tn916-related elements from Enterococcus faecalis to Escherichia coli and Pseudomonas fluorescens
Read more15 Sep 1994
publication
Heterogeneric conjugal transfer of the pheromone-responsive plasmid pIP964 (IncHlyI) of Enterococcus faecalis in the apparent absence of pheromone induction
Read more01 Dec 1993
publication
Study of heterogeneity of chloramphenicol acetyltransferase (CAT) genes in streptococci and enterococci by polymerase chain reaction: characterization of a new CAT determinant
Read more01 May 1993
publication
Enhanced conjugative transfer of plasmid DNA from Escherichia coli to Staphylococcus aureus and Listeria monocytogenes
Read more01 Apr 1993
publication
Sequence requirements for target activity in site-specific recombination mediated by the Int protein of transposon Tn 1545
Read more01 Nov 1992
publication
Nucleotide sequence of the chloramphenicol resistance determinant of the streptococcal plasmid pIP501
Read more01 Feb 1992
publication
Conjugal transfer of plasmid DNA from Enterococcus faecalis to Escherichia coli in digestive tracts of gnotobiotic mice
Read more01 Feb 1992
publication
Genetic basis of tetracycline resistance in clinical isolates of Listeria monocytogenes
Read more30 Sep 1991
publication
An integrative vector exploiting the transposition properties of Tn1545 for insertional mutagenesis and cloning of genes from gram-positive bacteria
Read more01 Aug 1991
publication
Nucleotide sequences specific for Tn1545-like conjugative transposons in pneumococci and staphylococci resistant to tetracycline
Read more01 Jul 1991
publication
Conjugative transposition of Tn916 requires the excisive and integrative activities of the transposon-encoded integrase
Read more15 Jun 1991
publication
Shuttle vectors containing a multiple cloning site and a lacZ alpha gene for conjugal transfer of DNA from Escherichia coli to gram-positive bacteria
Read more01 Jan 1991
publication
Inducible transfer of conjugative transposon Tn1545 from Enterococcus faecalis to Listeria monocytogenes in the digestive tracts of gnotobiotic mice
Read more01 Sep 1990
publication
The integration-excision system of the conjugative transposon Tn 1545 is structurally and functionally related to those of lambdoid phages
Read more25 Jul 1990
publication
A pair of mobilizable shuttle vectors conferring resistance to spectinomycin for molecular cloning in Escherichia coli and in gram-positive bacteria
Read more25 Jun 1990
publication
Nucleotide sequence of the erythromycin resistance gene of the conjugative transposon Tn1545
Read more16 Jun 1990
01 Aug 1989
publication
Molecular characterization of two proteins involved in the excision of the conjugative transposon Tn1545: homologies with other site-specific recombinases
Read more01 Jan 1989
01 Sep 1988
01 Jul 1988
01 Sep 1987
01 May 1987
publication
Nucleotide sequence of the kanamycin resistance determinant of the pneumococcal transposon Tn1545: evolutionary relationships and transcriptional analysis of aphA-3 genes
Read more01 Oct 1986
publication
Evolution and transfer of aminoglycoside resistance genes under natural conditions
Read more11 Sep 1986
publication
Nucleotide sequence of the tetM tetracycline resistance determinant of the streptococcal conjugative shuttle transposon Tn1545
Read more16 Dec 1985
publication
In vivo transfer of genetic information between gram-positive and gram-negative bacteria
Read more01 Sep 1985
publication
Structural relationship between the genes encoding 3′-aminoglycoside phosphotransferases in Campylobacter and in gram-positive cocci
Read more01 Jul 1985
publication
Transposition behavior of IS15 and its progenitor IS15-delta: are cointegrates exclusive end products?
Read more01 Jan 1985
publication
DNA sequences specifying the transcription of the streptococcal kanamycin resistance gene in Escherichia coli and Bacillus subtilis
Read more01 Oct 1984
01 Sep 1983
01 Sep 1983
publication
Nucleotide sequence of the Streptococcus faecalis plasmid gene encoding the 3’5″-aminoglycoside phosphotransferase type III
Read more01 Feb 1982
01 Jan 1982