Timeline

Thierry Pedron

Research Engineer

26 Sep 2024

publication

Biophysical insights into sugar-dependent medium acidification promoting YfaL protein-mediated Escherichia coli self-aggregation, biofilm formation and acid stress resistance.

04 Sep 2024

publication

Stable coexistence between an archaeal virus and the dominant methanogen of the human gut

01 Dec 2023

publication

Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human colonocytes.

15 Apr 2022

news

A recent study by the team of Laurent Debarbieux has been highlighted in the BIP (15/04/2022)

13 Apr 2022

publication

The gut environment regulates bacterial gene expression which modulates susceptibility to bacteriophage infection.

09 Sep 2020

publication

The Spatial Heterogeneity of the Gut Limits Predation and Fosters Coexistence of Bacteria and Bacteriophages.

31 Jul 2020

project

Oncobiomics – THE (heterogenity tumor ecosystem)

12 Jan 2016

project

Identification of a « crypt-specific core microbiota, CSCM » in human and murine intestine

15 Oct 2015

publication

Draft Genome Sequences of Acinetobacter parvus CM11, Acinetobacter radioresistens CM38, and Stenotrophomonas maltophilia BR12, Isolated from Murine Proximal Colonic Tissue

20 Mar 2015

publication

An O antigen capsule modulates bacterial pathogenesis in Shigella sonnei

16 Aug 2014

publication

Rapid 96-well plates DNA extraction and sequencing procedures to identify genome-wide transposon insertion sites in a difficult to lyse bacterium: Lactobacillus casei

14 Jul 2014

publication

Functional genomics of Lactobacillus casei establishment in the gut

12 Jun 2013

publication

Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis.

30 Apr 2013

publication

Epithelial cell proliferation arrest induced by lactate and acetate from Lactobacillus casei and Bifidobacterium breve

01 Apr 2013

publication

A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes

22 May 2012

publication

A crypt-specific core microbiota resides in the mouse colon

03 Feb 2012

publication

Microbes for Health 2 Symposium: meeting report

05 Mar 2009

publication

Characterisation of early mucosal and neuronal lesions following Shigella flexneri infection in human colon

12 Jun 2008

publication

Commensals, bacterial pathogens and intestinal inflammation: an intriguing ménage à trois

21 Apr 2008

publication

Virulent Shigella flexneri subverts the host innate immune response through manipulation of antimicrobial peptide gene expression

01 Apr 2008

publication

Maturation of paneth cells induces the refractory state of newborn mice to Shigella infection

01 Jan 2008

publication

Neutrophils in cystic fibrosis display a distinct gene expression pattern

10 Dec 2006

publication

An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses

15 Jan 2006

publication

Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells

01 Jan 2005

publication

Adherence modifies the regulation of gene expression induced by interleukin-10

01 Jul 2003

publication

A newborn mouse model for the study of intestinal pathogenesis of shigellosis

17 Jun 2003

publication

The invasive phenotype of Shigella flexneri directs a distinct gene expression pattern in the human intestinal epithelial cell line Caco-2

01 Jun 2003

publication

Anti-inflammatory role for intracellular dimeric immunoglobulin a by neutralization of lipopolysaccharide in epithelial cells

27 Mar 2003

publication

TLR4-dependent lipopolysaccharide-induced shedding of tumor necrosis factor receptors in mouse bone marrow granulocytes

15 Jan 2003

publication

Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulocytes via Toll-like receptor 2

01 Jan 2003

publication

Interaction of pulmonary surfactant protein C with CD14 and lipopolysaccharide

01 Oct 2002

publication

Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

01 Jul 2001

publication

Down-modulation of L-selectin by lipopolysaccharide is not required for lipopolysaccharide-induced expression of CD14 in mouse bone marrow granulocytes

15 Dec 2000

publication

Down-modulation through protein kinase C-alpha of lipopolysaccharide-induced expression of membrane CD14 in mouse bone marrow granulocytes

01 Oct 2000

publication

The lipid A region of lipopolysaccharides from Rhizobiaceae activates bone marrow granulocytes from lipopolysaccharide-hyporesponsive C3H/HeJ and C57BL/10ScCr mice

01 Jul 2000

publication

Protein phosphorylation pathways involved during lipopolysaccharide-induced expression of CD14 in mouse bone marrow granulocytes

01 Nov 1999

publication

Exogenous cyclic AMP, cholera toxin, and endotoxin induce expression of the lipopolysaccharide receptor CD14 in murine bone marrow cells: role of purinoreceptors

01 Oct 1997

publication

Lipopolysaccharide and the glycoside ring of staurosporine induce CD14 expression on bone marrow granulocytes by different mechanisms

01 Jul 1997

publication

Functional lipopolysaccharide receptors of low affinity are constitutively expressed on mouse bone marrow cells

01 Jun 1996

publication

Inability of the Francisella tularensis lipopolysaccharide to mimic or to antagonize the induction of cell activation by endotoxins

01 Aug 1995

publication

Variation of LPS-binding capacity, epitope expression, and shedding of membrane-bound CD14 during differentiation of human monocytes

28 Jan 1994

publication

Phosphatidylinositol-anchored molecules and inducible lipopolysaccharide binding sites of human and mouse bone marrow cells

01 Nov 1993

publication

Lipopolysaccharide and tumor necrosis factor-alpha induce lipopolysaccharide receptor expression on bone marrow cells by different mechanisms

01 Sep 1993

publication

A synthetic analog of the 3-deoxy-D-manno-2-octulosonic acid disaccharide moiety of rough-type endotoxins does not bind to mouse peritoneal macrophages and human monocytes

15 May 1993

publication

Endotoxin-induced expression of endotoxin binding sites on murine bone marrow cells

15 Apr 1993

publication

Differential effects of a monoclonal antibody recognizing 3-deoxy-D-manno-2-octulosonic acid on endotoxin-induced activation of pre-B cells and macrophages

01 Jan 1993

publication

Nontoxic forms of lipopolysaccharides, poorly cleared in vivo, are present in variable amounts in phenol-extracted endotoxins

01 Dec 1992

publication

Preparation and binding specificity of a monoclonal antibody recognizing 3-deoxy-D-manno-2-octulosonic acid (Kdo) in lipopolysaccharides of Re chemotype

01 Apr 1992

publication

New synthetic analogs of lipid A as lipopolysaccharide agonists or antagonists of B lymphocyte activation

01 Dec 1990

publication

The splenic pool of mouse stem cells: in vitro differentiation and expression of the BP-1 alloantigen on cells of the lymphoid and myeloid lineages

01 Dec 1989

publication

Effects of lipopolysaccharide on macrophages analyzed with anti-lipid A monoclonal antibodies and polymyxin B

01 Feb 1988

publication

Opposite effects of lipopolysaccharide and dextran sulfate on membrane phospholipid metabolism of murine B lymphocytes

13 Mar 1987

publication

A little guide for advanced search:

Biophysical insights into sugar-dependent medium acidification promoting YfaL protein-mediated Escherichia coli self-aggregation, biofilm formation and acid stress resistance.

Stable coexistence between an archaeal virus and the dominant methanogen of the human gut

Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human colonocytes.

A recent study by the team of Laurent Debarbieux has been highlighted in the BIP (15/04/2022)

The gut environment regulates bacterial gene expression which modulates susceptibility to bacteriophage infection.

The Spatial Heterogeneity of the Gut Limits Predation and Fosters Coexistence of Bacteria and Bacteriophages.

Oncobiomics – THE (heterogenity tumor ecosystem)

Identification of a « crypt-specific core microbiota, CSCM » in human and murine intestine

Draft Genome Sequences of Acinetobacter parvus CM11, Acinetobacter radioresistens CM38, and Stenotrophomonas maltophilia BR12, Isolated from Murine Proximal Colonic Tissue

An O antigen capsule modulates bacterial pathogenesis in Shigella sonnei

Rapid 96-well plates DNA extraction and sequencing procedures to identify genome-wide transposon insertion sites in a difficult to lyse bacterium: Lactobacillus casei

Functional genomics of Lactobacillus casei establishment in the gut

Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis.

Epithelial cell proliferation arrest induced by lactate and acetate from Lactobacillus casei and Bifidobacterium breve

A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes

A crypt-specific core microbiota resides in the mouse colon

Microbes for Health 2 Symposium: meeting report

Characterisation of early mucosal and neuronal lesions following Shigella flexneri infection in human colon

Commensals, bacterial pathogens and intestinal inflammation: an intriguing ménage à trois

Virulent Shigella flexneri subverts the host innate immune response through manipulation of antimicrobial peptide gene expression

Maturation of paneth cells induces the refractory state of newborn mice to Shigella infection

Neutrophils in cystic fibrosis display a distinct gene expression pattern

An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses

Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells

Adherence modifies the regulation of gene expression induced by interleukin-10

A newborn mouse model for the study of intestinal pathogenesis of shigellosis

The invasive phenotype of Shigella flexneri directs a distinct gene expression pattern in the human intestinal epithelial cell line Caco-2

Anti-inflammatory role for intracellular dimeric immunoglobulin a by neutralization of lipopolysaccharide in epithelial cells

TLR4-dependent lipopolysaccharide-induced shedding of tumor necrosis factor receptors in mouse bone marrow granulocytes

Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulocytes via Toll-like receptor 2

Interaction of pulmonary surfactant protein C with CD14 and lipopolysaccharide

Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

Down-modulation of L-selectin by lipopolysaccharide is not required for lipopolysaccharide-induced expression of CD14 in mouse bone marrow granulocytes

Down-modulation through protein kinase C-alpha of lipopolysaccharide-induced expression of membrane CD14 in mouse bone marrow granulocytes

The lipid A region of lipopolysaccharides from Rhizobiaceae activates bone marrow granulocytes from lipopolysaccharide-hyporesponsive C3H/HeJ and C57BL/10ScCr mice

Protein phosphorylation pathways involved during lipopolysaccharide-induced expression of CD14 in mouse bone marrow granulocytes

Exogenous cyclic AMP, cholera toxin, and endotoxin induce expression of the lipopolysaccharide receptor CD14 in murine bone marrow cells: role of purinoreceptors

Lipopolysaccharide and the glycoside ring of staurosporine induce CD14 expression on bone marrow granulocytes by different mechanisms

Functional lipopolysaccharide receptors of low affinity are constitutively expressed on mouse bone marrow cells

Inability of the Francisella tularensis lipopolysaccharide to mimic or to antagonize the induction of cell activation by endotoxins

Variation of LPS-binding capacity, epitope expression, and shedding of membrane-bound CD14 during differentiation of human monocytes

Phosphatidylinositol-anchored molecules and inducible lipopolysaccharide binding sites of human and mouse bone marrow cells

Lipopolysaccharide and tumor necrosis factor-alpha induce lipopolysaccharide receptor expression on bone marrow cells by different mechanisms

A synthetic analog of the 3-deoxy-D-manno-2-octulosonic acid disaccharide moiety of rough-type endotoxins does not bind to mouse peritoneal macrophages and human monocytes

Endotoxin-induced expression of endotoxin binding sites on murine bone marrow cells

Differential effects of a monoclonal antibody recognizing 3-deoxy-D-manno-2-octulosonic acid on endotoxin-induced activation of pre-B cells and macrophages

Nontoxic forms of lipopolysaccharides, poorly cleared in vivo, are present in variable amounts in phenol-extracted endotoxins

Preparation and binding specificity of a monoclonal antibody recognizing 3-deoxy-D-manno-2-octulosonic acid (Kdo) in lipopolysaccharides of Re chemotype

New synthetic analogs of lipid A as lipopolysaccharide agonists or antagonists of B lymphocyte activation

The splenic pool of mouse stem cells: in vitro differentiation and expression of the BP-1 alloantigen on cells of the lymphoid and myeloid lineages

Effects of lipopolysaccharide on macrophages analyzed with anti-lipid A monoclonal antibodies and polymyxin B

Opposite effects of lipopolysaccharide and dextran sulfate on membrane phospholipid metabolism of murine B lymphocytes

Antigenic determinants of lipid A analyzed with synthetic models and monoclonal antibodies