Timeline

Céline Loot

Group Leader

16 May 2025

publication

Sedentary chromosomal integrons as biobanks of bacterial antiphage defense systems

08 May 2025

publication

Sedentary chromosomal integrons as biobanks of bacterial antiphage defense systems.

13 Dec 2024

publication

The recombination efficiency of the bacterial integron depends on the mechanical stability of the synaptic complex.

11 Nov 2024

publication

Chromosomal integrons are genetically and functionally isolated units of genomes.

21 Oct 2024

publication

Fine-tuning of a CRISPRi screen in the seventh pandemic Vibrio cholerae.

10 Jul 2024

project

Defense systems in integrons: bacterial weapons in a bank (Definbank)

01 Apr 2024

publication

Belt and braces: Two escape ways to maintain the cassette reservoir of large chromosomal integrons.

17 Jan 2024

team

Adaptive dynamics of integrons

12 Jan 2024

publication

Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems.

03 Jan 2024

publication

Integron cassettes integrate into bacterial genomes via widespread non-classical attG sites.

22 Mar 2022

news

Back on: The “forum des métiers”, Collège et Lycée Camille Sée, Paris (France)

08 Mar 2022

publication

Unbridled Integrons: A Matter of Host Factors.

02 Feb 2022

project

Impact of chromosomal integrons on bacterial life and evolution (Chromintevol)

21 Dec 2021

news

GG speaks Microbes at the Ecole Saint Lambert (Paris 15ème arr.) – 16/12/2021

22 Oct 2021

news

Back on: Science Outreach during the Departmental retreat in Pornichet 2021

09 Jun 2021

news

Highlighted publication : “Cassette recruitment in the chromosomal Integron of Vibrio cholerae”, Vit et al., NAR, Bacterial Genome Plasticity team.

04 Jun 2021

publication

Cassette recruitment in the chromosomal Integron of Vibrio cholerae.

15 Dec 2020

publication

Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions.

01 Jul 2020

publication

Structure-specific DNA recombination sites: Design, validation, and machine learning–based refinement

01 Jan 2020

publication

Integron Identification in Bacterial Genomes and Cassette Recombination Assays.

28 Feb 2019

publication

Structural heterogeneity of attC integron recombination sites revealed by optical tweezers.

01 Jan 2018

publication

Recoding of synonymous genes to expand evolutionary landscapes requires control of secondary structure affecting translation.

28 Mar 2017

publication

Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance.

19 Sep 2016

publication

Efficiency of integron cassette insertion in correct orientation is ensured by the interplay of the three unpaired features of attC recombination sites.

01 Jul 2016

publication

Adaptation to Global Change: A Transposable Element-Epigenetics Perspective.

10 Mar 2016

publication

Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation.

09 Jun 2015

project

Integrons

11 May 2015

team

Bacterial Genome Plasticity

01 Apr 2015

publication

The Integron: Adaptation On Demand.

01 Feb 2014

publication

The integron integrase efficiently prevents the melting effect of Escherichia coli single-stranded DNA-binding protein on folded attC sites.

01 Sep 2012

publication

Replicative resolution of integron cassette insertion.

01 Dec 2010

publication

Folded DNA in action: hairpin formation and biological functions in prokaryotes.

04 Aug 2010

publication

Cellular pathways controlling integron cassette site folding.

01 Sep 2009

publication

Structural features of single-stranded integron cassette attC sites and their role in strand selection.

30 Aug 2008

publication

Different strategies to persist: the pogo-like Lemi1 transposon produces miniature inverted-repeat transposable elements or typical defective elements in different plant genomes.

A little guide for advanced search:

Sedentary chromosomal integrons as biobanks of bacterial antiphage defense systems

Sedentary chromosomal integrons as biobanks of bacterial antiphage defense systems.

The recombination efficiency of the bacterial integron depends on the mechanical stability of the synaptic complex.

Chromosomal integrons are genetically and functionally isolated units of genomes.

Fine-tuning of a CRISPRi screen in the seventh pandemic Vibrio cholerae.

Defense systems in integrons: bacterial weapons in a bank (Definbank)

Belt and braces: Two escape ways to maintain the cassette reservoir of large chromosomal integrons.

Adaptive dynamics of integrons

Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems.

Integron cassettes integrate into bacterial genomes via widespread non-classical attG sites.

Back on: The “forum des métiers”, Collège et Lycée Camille Sée, Paris (France)

Unbridled Integrons: A Matter of Host Factors.

Impact of chromosomal integrons on bacterial life and evolution (Chromintevol)

GG speaks Microbes at the Ecole Saint Lambert (Paris 15ème arr.) – 16/12/2021

Back on: Science Outreach during the Departmental retreat in Pornichet 2021

Highlighted publication : “Cassette recruitment in the chromosomal Integron of Vibrio cholerae”, Vit et al., NAR, Bacterial Genome Plasticity team.

Cassette recruitment in the chromosomal Integron of Vibrio cholerae.

Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions.

Structure-specific DNA recombination sites: Design, validation, and machine learning–based refinement

Integron Identification in Bacterial Genomes and Cassette Recombination Assays.

Structural heterogeneity of attC integron recombination sites revealed by optical tweezers.

Recoding of synonymous genes to expand evolutionary landscapes requires control of secondary structure affecting translation.

Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance.

Efficiency of integron cassette insertion in correct orientation is ensured by the interplay of the three unpaired features of attC recombination sites.

Adaptation to Global Change: A Transposable Element-Epigenetics Perspective.

Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation.

Integrons

Bacterial Genome Plasticity

The Integron: Adaptation On Demand.

The integron integrase efficiently prevents the melting effect of Escherichia coli single-stranded DNA-binding protein on folded attC sites.

Replicative resolution of integron cassette insertion.

Folded DNA in action: hairpin formation and biological functions in prokaryotes.

Cellular pathways controlling integron cassette site folding.

Structural features of single-stranded integron cassette attC sites and their role in strand selection.

Different strategies to persist: the pogo-like Lemi1 transposon produces miniature inverted-repeat transposable elements or typical defective elements in different plant genomes.