Timeline

Undine Mechold
Group Leader
25 Sep 2023
publication

Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin

Read more
16 Nov 2021
publication

Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens.

Read more
26 Mar 2020
team

Group : Actin-activated nucleotidyl cyclases

Read more
12 Nov 2018
publication

Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin

Read more
30 Oct 2018
publication

The extreme C terminus of the effector ExoY is crucial for binding to its eukaryotic activator, F-actin

Read more
05 Sep 2018
event

PhD thesis: ExoY, une toxine nucléotidyl cyclase de Pseudomonas aeruginosa

Read more
16 Dec 2017
publication

ExoY, an actin-activated nucleotidyl cyclase toxin from P. aeruginosa: A minireview

Read more
13 Mar 2017
event

Ina Attrée seminar

Read more
05 Dec 2016
publication

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

Read more
24 Aug 2015
publication

Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa

Read more
08 Jul 2015
project

Regulatory roles of signaling Nucleotides

Read more
11 May 2015
team

Biochemistry of Macromolecular Interactions

Read more
23 Jan 2014
publication

Two-step synthesis and hydrolysis of cyclic di-AMP in Mycobacterium tuberculosis

Read more
25 Apr 2013
publication

Differential regulation by ppGpp versus pppGpp in Escherichia coli

Read more
15 Apr 2012
publication

3′-5′ phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo

Read more
19 Jan 2012
publication

Identification of a novel nanoRNase in Bartonella

Read more
23 Nov 2011
publication

Characterization of NrnA homologs from Mycobacterium tuberculosis and Mycoplasma pneumoniae

Read more
01 Nov 2009
publication

Analysis of interaction partners of H4 histone by a new proteomics approach

Read more
24 Jun 2009
publication

Degradation of nanoRNA is performed by multiple redundant RNases in Bacillus subtilis

Read more
15 Sep 2008
publication

Multiple displacement amplification for complex mixtures of DNA fragments

Read more
22 Jun 2007
publication

YtqI from Bacillus subtilis has both oligoribonuclease and pAp-phosphatase activity

Read more
01 Jul 2006
publication

Analysis of human histone H2AZ deposition in vivo argues against its direct role in epigenetic templating mechanisms

Read more
08 May 2006
publication

Oligoribonuclease is a common downstream target of lithium-induced pAp accumulation in Escherichia coli and human cells

Read more
17 Jan 2005
publication

Codon optimization of the BirA enzyme gene leads to higher expression and an improved efficiency of biotinylation of target proteins in mammalian cells

Read more
01 Apr 2004
publication

Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response [corrected]

Read more
01 Feb 2004
publication

Use of protein biotinylation in vivo for chromatin immunoprecipitation

Read more
02 Dec 2003
publication

Inducible expression, enzymatic activity, and origin of higher plant homologues of bacterial RelA/SpoT stress proteins in Nicotiana tabacum

Read more
01 Jun 2002
publication

Intramolecular regulation of the opposing (p)ppGpp catalytic activities of Rel(Seq), the Rel/Spo enzyme from Streptococcus equisimilis

Read more
01 Jul 1998
publication

The role of the Corynebacterium glutamicum rel gene in (p)ppGpp metabolism

Read more
01 Apr 1997
publication

Characterization of the stringent and relaxed responses of Streptococcus equisimilis

Read more
01 Jan 1997
publication

Elicitation of high (p)ppGpp levels in Streptococcus equisimilis without imposing nutritional deprivation

Read more
01 Mar 1996
publication

Functional analysis of a relA/spoT gene homolog from Streptococcus equisimilis

Read more
01 Jan 1995
publication

The streptokinase gene: allelic variation, genomic environment and expression control

Read more
01 Feb 1994
publication

Inactivation of the streptokinase gene prevents Streptococcus equisimilis H46A from acquiring cell-associated plasmin activity in the presence of plasminogen

Read more
01 Oct 1993
publication

Genetic organization of the streptokinase region of the Streptococcus equisimilis H46A chromosome

Read more