Ligne de temps

Undine Mechold
Chef(fe) de Groupe
25 sept. 2023
publication

Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin

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16 nov. 2021
publication

Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens.

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26 mars 2020
team

Groupe : Undine Mechold

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12 nov. 2018
publication

Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin

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30 oct. 2018
publication

The extreme C terminus of the effector ExoY is crucial for binding to its eukaryotic activator, F-actin

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05 sept. 2018
event

PhD thesis: ExoY, une toxine nucléotidyl cyclase de Pseudomonas aeruginosa

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16 déc. 2017
publication

ExoY, an actin-activated nucleotidyl cyclase toxin from P. aeruginosa: A minireview

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13 mars 2017
event

Ina Attrée seminar

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05 déc. 2016
publication

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

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24 août 2015
publication

Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa

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08 juil. 2015
project

Regulatory roles of signaling Nucleotides

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11 mai 2015
team

Biochimie des Interactions Macromoléculaires

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23 janv. 2014
publication

Two-step synthesis and hydrolysis of cyclic di-AMP in Mycobacterium tuberculosis

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25 avr. 2013
publication

Differential regulation by ppGpp versus pppGpp in Escherichia coli

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15 avr. 2012
publication

3′-5′ phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo

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19 janv. 2012
publication

Identification of a novel nanoRNase in Bartonella

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23 nov. 2011
publication

Characterization of NrnA homologs from Mycobacterium tuberculosis and Mycoplasma pneumoniae

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01 nov. 2009
publication

Analysis of interaction partners of H4 histone by a new proteomics approach

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24 juin 2009
publication

Degradation of nanoRNA is performed by multiple redundant RNases in Bacillus subtilis

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15 sept. 2008
publication

Multiple displacement amplification for complex mixtures of DNA fragments

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22 juin 2007
publication

YtqI from Bacillus subtilis has both oligoribonuclease and pAp-phosphatase activity

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01 juil. 2006
publication

Analysis of human histone H2AZ deposition in vivo argues against its direct role in epigenetic templating mechanisms

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08 mai 2006
publication

Oligoribonuclease is a common downstream target of lithium-induced pAp accumulation in Escherichia coli and human cells

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17 janv. 2005
publication

Codon optimization of the BirA enzyme gene leads to higher expression and an improved efficiency of biotinylation of target proteins in mammalian cells

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01 avr. 2004
publication

Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response [corrected]

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01 févr. 2004
publication

Use of protein biotinylation in vivo for chromatin immunoprecipitation

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02 déc. 2003
publication

Inducible expression, enzymatic activity, and origin of higher plant homologues of bacterial RelA/SpoT stress proteins in Nicotiana tabacum

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01 juin 2002
publication

Intramolecular regulation of the opposing (p)ppGpp catalytic activities of Rel(Seq), the Rel/Spo enzyme from Streptococcus equisimilis

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01 juil. 1998
publication

The role of the Corynebacterium glutamicum rel gene in (p)ppGpp metabolism

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01 avr. 1997
publication

Characterization of the stringent and relaxed responses of Streptococcus equisimilis

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01 janv. 1997
publication

Elicitation of high (p)ppGpp levels in Streptococcus equisimilis without imposing nutritional deprivation

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01 mars 1996
publication

Functional analysis of a relA/spoT gene homolog from Streptococcus equisimilis

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01 janv. 1995
publication

The streptokinase gene: allelic variation, genomic environment and expression control

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01 févr. 1994
publication

Inactivation of the streptokinase gene prevents Streptococcus equisimilis H46A from acquiring cell-associated plasmin activity in the presence of plasminogen

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01 oct. 1993
publication

Genetic organization of the streptokinase region of the Streptococcus equisimilis H46A chromosome

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