Timeline

Alphonse Garcia
Permanent Researcher
28 Sep 2017
team

Design for Biology

Read more
26 Oct 2015
project

PP2A1 is a target for Alzheimer disease

Read more
26 Oct 2015
project

PP2A a key target for viruses

Read more
17 Oct 2015
project

The trimeric ABαC phosphatase named PP2A1 is a target for cancer therapy

Read more
17 Sep 2015
project

PP2A a key target for viruses

Read more
14 Mar 2013
publication

Transducing properties of a pre-structured α-helical DPT-peptide containing a short canine adenovirus type 2 E4orf4 PP2A1-binding sequence

Read more
23 Dec 2011
publication

[Targeting of PP2A enzymes by viral proteins and cancer signalling]

Read more
10 Aug 2011
publication

PP2A targeting by viral proteins: a widespread biological strategy from DNA/RNA tumor viruses to HIV-1

Read more
01 Nov 2010
publication

PP2A1 binding, cell transducing and apoptotic properties of Vpr(77-92): a new functional domain of HIV-1 Vpr proteins

Read more
01 Apr 2010
publication

The combinatorial PP1-binding consensus Motif (R/K)x( (0,1))V/IxFxx(R/K)x(R/K) is a new apoptotic signature

Read more
24 Feb 2010
publication

Sustained gonadotropin-releasing hormone stimulation mobilizes the cAMP/PKA pathway to induce nitric oxide synthase type 1 expression in rat pituitary cells in vitro and in vivo at proestrus

Read more
17 Jan 2007
publication

Functional interaction of Aurora-A and PP2A during mitosis

Read more
01 Aug 2006
publication

A PKA survival pathway inhibited by DPT-PKI, a new specific cell permeable PKA inhibitor, is induced by T. annulata in parasitized B-lymphocytes

Read more
30 Dec 2005
publication

Use of penetrating peptides interacting with PP1/PP2A proteins as a general approach for a drug phosphatase technology

Read more
01 Dec 2004
publication

Bad-dependent rafts alteration is a consequence of an early intracellular signal triggered by interleukin-4 deprivation

Read more
01 Feb 2004
publication

New insights in protein phosphorylation: a signature for protein phosphatase 1 interacting proteins

Read more
01 Aug 2003
publication

Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosis

Read more
01 Aug 2003
publication

Apoptosis of Theileria-infected lymphocytes induced upon parasite death involves activation of caspases 9 and 3

Read more
01 Aug 2003
publication

Protein phosphatase 2A as a new target for morphogenetic studies in the chick limb

Read more
01 Aug 2003
publication

Rafts: a simple way to control apoptosis by subcellular redistribution

Read more
06 Feb 2003
publication

Actin dynamics is controlled by a casein kinase II and phosphatase 2C interplay on Toxoplasma gondii Toxofilin

Read more
01 Jul 2002
publication

The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad

Read more
01 Apr 2002
publication

Segregation of Bad from lipid rafts is implicated in the induction of apoptosis

Read more
01 Mar 2002
publication

A role for Toxoplasma gondii type 1 ser/thr protein phosphatase in host cell invasion

Read more
15 Jun 2001
publication

Bcl-2 targets protein phosphatase 1 alpha to Bad

Read more
22 Sep 2000
publication

A novel role for protein phosphatase 2A in the dopaminergic regulation of Na,K-ATPase

Read more
01 Sep 2000
publication

A Theileria parva type 1 protein phosphatase activity

Read more
31 Mar 2000
publication

Protein phosphatase 2A and phosphatidylinositol 3-kinase regulate the activity of Sp1-responsive promoters

Read more
01 Mar 1999
publication

A family of PP2 phosphatases in Plasmodium falciparum and parasitic protozoa

Read more
10 Sep 1998
publication

The Bcl-2 gene is differentially regulated by IL-2 and IL-4: role of the transcription factor NF-AT

Read more
01 Nov 1997
publication

The glucocorticoid receptor and AP-1 are involved in a positive regulation of the muscle regulatory gene myf5 in cultured myoblasts

Read more
01 Nov 1997
publication

Rho prevents apoptosis through Bcl-2 expression: implications for interleukin-2 receptor signal transduction

Read more
15 Sep 1997
publication

Protein phosphatase 2A is a critical regulator of protein kinase C zeta signaling targeted by SV40 small t to promote cell growth and NF-kappaB activation

Read more
01 Jul 1997
publication

Ras activation leads to cell proliferation or apoptotic cell death upon interleukin-2 stimulation or lymphokine deprivation, respectively

Read more
01 Jun 1997
publication

Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity

Read more
01 May 1997
publication

Wortmannin inhibits IGF-dependent differentiation in the mouse myogenic cell line C2

Read more
15 Feb 1997
publication

IL-2 signaling controls actin organization through Rho-like protein family, phosphatidylinositol 3-kinase, and protein kinase C-zeta

Read more
15 Sep 1996
publication

Critical role of Ras in the proliferation and prevention of apoptosis mediated by IL-2

Read more
01 Aug 1996
publication

Association of phosphatidylinositol 3 kinase to protein kinase C zeta during interleukin-2 stimulation

Read more
01 Mar 1996
publication

Human cytomegalovirus carries serine/threonine protein phosphatases PP1 and a host-cell derived PP2A

Read more
01 Dec 1995
publication

HIV genome transcription induced by polyoma virus middle T antigen through both enhancer- and promoter-dependent LTR activation

Read more
01 Sep 1995
publication

Physical association and functional relationship between protein kinase C zeta and the actin cytoskeleton

Read more
20 Jul 1995
publication

Structure and chromosomal localization of the human gene of the phosphotyrosyl phosphatase activator (PTPA) of protein phosphatase 2A

Read more
01 May 1995
publication

The zeta isoform of protein kinase C controls interleukin-2-mediated proliferation in a murine T cell line: evidence for an additional role of protein kinase C epsilon and beta

Read more
20 Apr 1995
publication

Induction of Sp1 phosphorylation and NF-kappa B-independent HIV promoter domain activity in T lymphocytes stimulated by okadaic acid

Read more
01 Apr 1995
publication

Differential effect of rapamycin and cyclosporin A in proliferation in a murine T cell line expressing either intermediate or high affinity receptor for IL-2

Read more
01 Mar 1995
publication

A role for the intermediate affinity IL-2R in the protection against glucocorticoid-induced apoptosis

Read more
01 Jul 1994
publication

Implication of protein kinase C in IL-2-mediated proliferation and apoptosis in a murine T cell clone

Read more
01 Jul 1993
publication

High-affinity and intermediate-affinity forms of the human interleukin 2 receptor, expressed in an interleukin 9-dependent murine T cell line, deliver proliferative signals via differences in their transduction pathways

Read more
01 Dec 1989
publication

Partial deduced sequence of the 110-kD-calmodulin complex of the avian intestinal microvillus shows that this mechanoenzyme is a member of the myosin I family

Read more
01 Nov 1988
publication

Sequence of human villin: a large duplicated domain homologous with other actin-severing proteins and a unique small carboxy-terminal domain related to villin specificity

Read more
01 Jan 1988
publication

Villin, a specific marker for some epithelia specialized in transport, to study the differentiation of intestinal and kidney cells in vivo and in a human colon adenocarcinoma line HT29 in culture

Read more
01 Dec 1986
publication

A human villin cDNA clone to investigate the differentiation of intestinal and kidney cells in vivo and in culture

Read more
01 Aug 1980
publication

Nuclear processing of viral high-molecular-weight RNA in cells infected with herpes simplex virus type 1

Read more