Ligne de temps

Alphonse Garcia
Chercheur(euse) Permanent(e)
28 sept. 2017
team

Design de la Biologie

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26 oct. 2015
project

PP2A1 is a target for Alzheimer disease

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26 oct. 2015
project

PP2A a key target for viruses

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17 oct. 2015
project

The trimeric ABαC phosphatase named PP2A1 is a target for cancer therapy

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17 sept. 2015
project

PP2A a key target for viruses

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14 mars 2013
publication

Transducing properties of a pre-structured α-helical DPT-peptide containing a short canine adenovirus type 2 E4orf4 PP2A1-binding sequence

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23 déc. 2011
publication

[Targeting of PP2A enzymes by viral proteins and cancer signalling]

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10 août 2011
publication

PP2A targeting by viral proteins: a widespread biological strategy from DNA/RNA tumor viruses to HIV-1

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01 nov. 2010
publication

PP2A1 binding, cell transducing and apoptotic properties of Vpr(77-92): a new functional domain of HIV-1 Vpr proteins

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01 avr. 2010
publication

The combinatorial PP1-binding consensus Motif (R/K)x( (0,1))V/IxFxx(R/K)x(R/K) is a new apoptotic signature

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24 févr. 2010
publication

Sustained gonadotropin-releasing hormone stimulation mobilizes the cAMP/PKA pathway to induce nitric oxide synthase type 1 expression in rat pituitary cells in vitro and in vivo at proestrus

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17 janv. 2007
publication

Functional interaction of Aurora-A and PP2A during mitosis

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01 août 2006
publication

A PKA survival pathway inhibited by DPT-PKI, a new specific cell permeable PKA inhibitor, is induced by T. annulata in parasitized B-lymphocytes

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30 déc. 2005
publication

Use of penetrating peptides interacting with PP1/PP2A proteins as a general approach for a drug phosphatase technology

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01 déc. 2004
publication

Bad-dependent rafts alteration is a consequence of an early intracellular signal triggered by interleukin-4 deprivation

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01 févr. 2004
publication

New insights in protein phosphorylation: a signature for protein phosphatase 1 interacting proteins

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01 août 2003
publication

Rafts: a simple way to control apoptosis by subcellular redistribution

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01 août 2003
publication

Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosis

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01 août 2003
publication

Apoptosis of Theileria-infected lymphocytes induced upon parasite death involves activation of caspases 9 and 3

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01 août 2003
publication

Protein phosphatase 2A as a new target for morphogenetic studies in the chick limb

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06 févr. 2003
publication

Actin dynamics is controlled by a casein kinase II and phosphatase 2C interplay on Toxoplasma gondii Toxofilin

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01 juil. 2002
publication

The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad

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01 avr. 2002
publication

Segregation of Bad from lipid rafts is implicated in the induction of apoptosis

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01 mars 2002
publication

A role for Toxoplasma gondii type 1 ser/thr protein phosphatase in host cell invasion

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15 juin 2001
publication

Bcl-2 targets protein phosphatase 1 alpha to Bad

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22 sept. 2000
publication

A novel role for protein phosphatase 2A in the dopaminergic regulation of Na,K-ATPase

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01 sept. 2000
publication

A Theileria parva type 1 protein phosphatase activity

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31 mars 2000
publication

Protein phosphatase 2A and phosphatidylinositol 3-kinase regulate the activity of Sp1-responsive promoters

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01 mars 1999
publication

A family of PP2 phosphatases in Plasmodium falciparum and parasitic protozoa

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10 sept. 1998
publication

The Bcl-2 gene is differentially regulated by IL-2 and IL-4: role of the transcription factor NF-AT

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01 nov. 1997
publication

The glucocorticoid receptor and AP-1 are involved in a positive regulation of the muscle regulatory gene myf5 in cultured myoblasts

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01 nov. 1997
publication

Rho prevents apoptosis through Bcl-2 expression: implications for interleukin-2 receptor signal transduction

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15 sept. 1997
publication

Protein phosphatase 2A is a critical regulator of protein kinase C zeta signaling targeted by SV40 small t to promote cell growth and NF-kappaB activation

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01 juil. 1997
publication

Ras activation leads to cell proliferation or apoptotic cell death upon interleukin-2 stimulation or lymphokine deprivation, respectively

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01 juin 1997
publication

Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity

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01 mai 1997
publication

Wortmannin inhibits IGF-dependent differentiation in the mouse myogenic cell line C2

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15 févr. 1997
publication

IL-2 signaling controls actin organization through Rho-like protein family, phosphatidylinositol 3-kinase, and protein kinase C-zeta

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15 sept. 1996
publication

Critical role of Ras in the proliferation and prevention of apoptosis mediated by IL-2

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01 août 1996
publication

Association of phosphatidylinositol 3 kinase to protein kinase C zeta during interleukin-2 stimulation

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01 mars 1996
publication

Human cytomegalovirus carries serine/threonine protein phosphatases PP1 and a host-cell derived PP2A

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01 déc. 1995
publication

HIV genome transcription induced by polyoma virus middle T antigen through both enhancer- and promoter-dependent LTR activation

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01 sept. 1995
publication

Physical association and functional relationship between protein kinase C zeta and the actin cytoskeleton

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20 juil. 1995
publication

Structure and chromosomal localization of the human gene of the phosphotyrosyl phosphatase activator (PTPA) of protein phosphatase 2A

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01 mai 1995
publication

The zeta isoform of protein kinase C controls interleukin-2-mediated proliferation in a murine T cell line: evidence for an additional role of protein kinase C epsilon and beta

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20 avr. 1995
publication

Induction of Sp1 phosphorylation and NF-kappa B-independent HIV promoter domain activity in T lymphocytes stimulated by okadaic acid

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01 avr. 1995
publication

Differential effect of rapamycin and cyclosporin A in proliferation in a murine T cell line expressing either intermediate or high affinity receptor for IL-2

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01 mars 1995
publication

A role for the intermediate affinity IL-2R in the protection against glucocorticoid-induced apoptosis

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01 juil. 1994
publication

Implication of protein kinase C in IL-2-mediated proliferation and apoptosis in a murine T cell clone

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01 juil. 1993
publication

High-affinity and intermediate-affinity forms of the human interleukin 2 receptor, expressed in an interleukin 9-dependent murine T cell line, deliver proliferative signals via differences in their transduction pathways

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01 déc. 1989
publication

Partial deduced sequence of the 110-kD-calmodulin complex of the avian intestinal microvillus shows that this mechanoenzyme is a member of the myosin I family

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01 nov. 1988
publication

Sequence of human villin: a large duplicated domain homologous with other actin-severing proteins and a unique small carboxy-terminal domain related to villin specificity

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01 janv. 1988
publication

Villin, a specific marker for some epithelia specialized in transport, to study the differentiation of intestinal and kidney cells in vivo and in a human colon adenocarcinoma line HT29 in culture

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01 déc. 1986
publication

A human villin cDNA clone to investigate the differentiation of intestinal and kidney cells in vivo and in culture

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01 août 1980
publication

Nuclear processing of viral high-molecular-weight RNA in cells infected with herpes simplex virus type 1

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