Groups Laboratory Structural Virology Félix A. Rey Laboratory RNA Biology of Influenza Virus Nadia Naffakh Laboratory Virus sensing and signaling Nolwenn Jouvenet
Members Nadia Naffakh Head of Structure Head Nolwenn Jouvenet Head of Structure Head Félix A. Rey Head of Structure Marie-Christine Vaney Permanent Researcher Stéphane Duquerroy Permanent Researcher Giovanna Barba-Spaeth Group Leader Marija Backovic Group Leader Bertrand Saunier Permanent Researcher Marie Flamand Group Leader François Bontems Permanent Researcher Annalisa Meola Research Engineer Carole Tamietti Technician Delphine Brun Technician Arvind Sharma Post-doc Ignacio Fernandez Post-doc Andres Ferrino Iriarte PhD Student Charlotte Romanet PhD Student Marie-Claire Rozier Administrative Staff Atousa Arbabian Post-doc Marine Hurard Project Manager Nadia Naffakh Head of Structure Sandie Munier Catherine Isel-Griffiths Permanent Researcher Usama Ashraf PhD Student Kuang-Yu Chen PhD Student Nicolas Malausse PhD Student Tim Krischuns Post-doc Sylvain Paisant Technician Nolwenn Jouvenet Head of Structure Maxime Chazal Research Engineer Ségolène Gracias Research Engineer Vincent Caval Permanent Researcher Maël Bessaud Director of Center Typhaine Filhol PhD Student Samuel DONAIRE-CARPIO PhD Student Chloë Delon PhD Student Charlotte Baliere Research Engineer Corentin Aubé Post-doc LE SEAC H Elodie Research Engineer Hanna JUHOOR Administrative Staff Justine Maubrou Technician Léa VENDRAMINI Technician Julie DELAROCHE Research Engineer Aïssatou Aïcha SOW Post-doc Thomas FOULON Administrative Staff Valérie Granata Administrative Staff
Publications Download 2025 Curaudeau M, Kerbis Peterhans J, Le Flanchec T, Gilissen E, Granjon L, Barale L, Gessain A, Hassanin A, Squirrel reservoirs of monkeypox virus are sister species separated by the Sanaga River (Cameroon), as are the two main viral clades., One Health 2025 Dec; 21(): 101157. 2025 Holoubek J, Salát J, Matkovic M, Bednář P, Novotný P, Hradilek M, Majerová T, Rosendal E, Eyer L, Fořtová A, Beránková M, Bell-Sakyi L, Överby AK, Cavalli A, Bonomi M, Rey FA, Růžek D, Irreversible furin cleavage site exposure renders immature tick-borne flaviviruses fully infectious., Nat Commun 2025 Aug; 16(1): 7491. 2025 Beretta M, Martin E, Fogel O, López-Medina C, Planchais C, Bruneau T, Goncalves P, Avouac J, Berenbaum F, Sellam J, Fautrel B, Morel J, Parfait B, Di Santo JP, Behillil S, van der Werf S, Péré H, Latour S, Mouquet H, Miceli-Richard C, Adaptive immune responses to SARS-CoV-2 in DMARD-treated patients with chronic inflammatory rheumatisms., RMD Open 2025 Jul; 11(3): . 2025 Alemany C, Da Graça J, Giai Gianetto Q, Dupont M, Paisant S, Douché T, Isel C, Delevoye C, Danglot L, Matondo M, Morel E, Brault JB, Naffakh N, Influenza A virus induces PI4P production at the endoplasmic reticulum in an ATG16L1-dependent manner to promote the egress of viral ribonucleoproteins., PLoS Biol 2025 Jul; 23(7): e3002958. 2025 Vincent Legros, Essia Belarbi, Patricia Jeannin, Virginie Geolier, Beate Kümmerer, David Hardy, Philippe Desprès, Antoine Gessain, Pierre Roques, Pierre-Emmanuel Ceccaldi, Valérie Choumet, Use of Recombinant Chikungunya Virus expressing Nanoluciferase to Identify Chondrocytes as Target Cells in an Immunocompetent Mouse Model, Journal of Infectious Diseases, In press, pp.jiaf232. ⟨10.1093/infdis/jiaf232⟩. 2025 Saha P, Fernandez I, Sumbul F, Valotteau C, Kostrz D, Meola A, Baquero E, Sharma A, Portman JR, Stransky F, Boudier T, Guardado-Calvo P, Gosse C, Strick T, Rey FA, Rico F, Modulation of SARS-CoV-2 spike binding to ACE2 through conformational selection., Nat Nanotechnol 2025 Jul; 20(7): 926-934. 2025 Fletcher SJ, Bardossy ES, Tomé-Poderti L, Moss T, Mongelli V, Frangeul L, Blanc H, Verdier Y, Vinh J, Mukherjee S, Saleh MC, Hsc70-4: An unanticipated mediator of dsRNA internalization in Drosophila., Sci Adv 2025 May; 11(20): eadv1286. 2025 Dugied G, Laurent EM, Attia M, Gimeno JP, Bachiri K, Samavarchi-Tehrani P, Donati F, Rahou Y, Munier S, Amara F, Dos Santos M, Soler N, Volant S, Pietrosemoli N, Gingras AC, Pavlopoulos GA, van der Werf S, Falter-Braun P, Aloy P, Jacob Y, Komarova A, Sofianatos Y, Coyaud E, Demeret C, Multimodal SARS-CoV-2 interactome sketches the virus-host spatial organization., Commun Biol 2025 Mar; 8(1): 501. 2025 Suspène R, Caval V, Khalfi P, Pitré E, Marchio A, Pineau P, Vartanian JP, Cobalt chloride-mimicked hepatocyte cell hypoxia induces TREX1 leading to Hepatitis B virus restriction., J Infect Dis 2025 Jan; (): . 2025 Vernuccio R, Martínez León A, Poojari CS, Buchrieser J, Selverian CN, Jaleta Y, Meola A, Guivel-Benhassine F, Porrot F, Haouz A, Chevreuil M, Raynal B, Mercer J, Simon-Loriere E, Chandran K, Schwartz O, Hub JS, Guardado-Calvo P, Structural insights into tecovirimat antiviral activity and poxvirus resistance., Nat Microbiol 2025 Mar; 10(3): 734-748. + View full list of publications