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© Research
Member: Permanent Researcher

Marija Backovic

• Structural Virology

Scientific Fields
Diseases
Organisms
Applications
Technique

About

I study proteins involved in entry of herpesviruses and retroviruses. Some of these viral glycoproteins mediate fusion of viral and cellular membranes to allow viral entry, and some are involved in binding to cellular receptors or regulation of the fusion mechanism. I am also interested in cellular fusion proteins that have viral origins, such as syncytins which derive from env of retroviruses endogenized by humans tens of millions years ago.

Projects

CV

EDUCATION AND PROFESSIONAL APPOINTMENTS:  

2012 – present:

Senior research scientist in the lab of Félix REY (Pasteur Institute, Department of Virology)

Projects:

  • Structural and biochemical studies of envelope glycoproteins of herpesviruses
  • Structural studies of syncytins and other endogenous retroviral fusion proteins

2010 – 2012:

Junior research scientist in the lab of Félix REY (Pasteur Institute, Department of Virology)

Projects:

  • Structural and biochemical studies of envelope glycoproteins of herpesviruses

2008-2010:

Postdoctoral fellow in the lab of Félix REY (Pasteur Institute, Department of Virology)

Projects:

  • Structural and biochemical studies of fusion proteins of herpesviruses

2004-2008:

Postdoctoral fellow in the lab of Theodore JARDETZKY (Northwestern University, USA)

Projects: 

  • Structural and functional studies of Epstein-Barr virus glycoprotein B (gB) (collaboration with Richard Longnecker, Robert Lamb, Northwestern University)

1998-2003:

Ph.D. student under supervision of Peter G.W. GETTINS (University of Illinois at Chicago, Department of Biochemistry and Molecular Genetics, Chicago, USA)

  • Thesis: “The serpin inhibition mechanism and unique functions of antithrombin” (GPA 5.0/5.0)

1993-1998:

Undergraduate student, B.Sc. in Biochemistry, University of Belgrade, Department of Biochemistry, Serbia 

Publications

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