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  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
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  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
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Scientific Fields
Diseases
Organisms
Applications
Technique

About

The Ecology and Evolution of Antibiotic Resistance (EERA) Unit aims at characterizing factors contributing to the emergence and the dissemination of antibiotic resistance clones in the hospital and in the community. Our research projects focus on Enterobacteriaceae resistant to carbapenems and/or expressing extended spectrum b-lactamases. These isolates represent today one of the most urgent public health threats because of their dramatic increase throughout the world. To address this issue, we are analyzing the evolutionary changes leading to the successful dissemination of specific clones, and the interaction of antibiotic resistant strains with the gut microbiota. We are also searching for the intrinsic factors of these clones contributing to resistance, increased fitness and to a greater capacity to disseminate in the human host and the in the environment. We are combining in silico studies based on comparative genomics, epidemiology, phylogenomics and mathematical modeling with functional studies of bacterial physiology and regulation. The Unit is located at the Institut Pasteur and at the Bicêtre Hospital, and is a joint structure between the Institut Pasteur, the Assistance Public Hôpitaux de Paris (APHP) and the University Paris Sud. Establishing a link between research and clinical cases is a key focus of our research.

Former Members

2000
2000
Name
Position
2016
2019
Violette Da Cunha
Post-doc
2016
2019
Elisabeth Sauvage
2016
2019
Pierre-Emmanuel Douarre
2016
2019
Alexandre Santos Almeida
2016
2019
Marie-Dominique Aytac
Administrative Staff
2016
2019
Vesna Mellon
Administrative Staff
2018
2019
Rafaël Patino-Navarrete
Post-doc
2018
2021
Adriana Chiarelli
PhD student
2020
2022
Virginie Guérin
Post-doc

Projects

Transversal Project

Publications

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