Philippe J. Sansonetti, MS, MD, is a microbiologist, Professor at the Pasteur Institute and the Collège de France in Paris. He is the Director of the Inserm Unit 1202 and of the Institut Pasteur […]
Intracellular traffic and cell compartmentalization Eukaryotic cells contain extensive internal membranes defining many compartments having each specific functions. However these organelles are constantly moving and reshaping, still retaining their identity. The maintenance of cell […]
Since the beginning of my career, my goal has been to understand the mechanisms of effector immune responses to viruses and the related viral countermeasures. During my thesis, I studied the origin of type […]
My interest is to investigate the pathogenesis of infectious diseases induced by bacteria in respiratory and reproductive systems. Particularly, I focus on pathogen-host interaction and try to understand the mechanisms by which host responses […]
Dr. Gerald Späth currently holds a Research Director position at the Institut Pasteur in Paris, where he directs the Unit ‘Parasitologie moléculaire et Signalisation’ (12 members) and the Department ‘Parasites and Insect Vectors’ (ca. […]
Dr. Najma Rachidi is a senior Researcher and the leader of the molecular parasitology team in the PARSIG unit. Her team investigates Host-pathogen interactions to (i) understand how Leishmania survives in immune cells, which […]
We are exploring interactions between flaviviruses (Yellow fever, Dengue, Zika and West Nile viruses) and their mammalian and arthropod-hosts. On-going projects focus on deciphering mechanisms underlying virus-induced innate immunity and inflammation, using biochemical, virological […]
Virus-host ribonucleoprotein complexes and innate immunity The RIG-I-like receptors (RLRs) play a major role in sensing intracytoplasmic RNA virus infection to initiate and modulate antiviral immunity. These RNA helicases interact with particular signatures of […]
