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Impact of gut mechanical forces and 3D architecture on the intestine homeostasis during pathogen interaction and in cancer disease
Nathalie Sauvonnet (PI)
The intestine, and in particular the colon, comprising a mucus blanket, an epithelial monolayer and the lamina propria rich in immune cells, is constantly subjected to shear stress (flow) and peristaltic motion (stretching), both […]
2019promotes major alteration of gut epithelial physiology and tissue invasion by shutting off host intracellular transport, Proc. Natl. Acad. Sci. U.S.A. 2019 Jul;116(27):13582-13591.
2017Colorectal cancer specific conditions promote gut colonization, Proc. Natl. Acad. Sci. U.S.A. 2018 01;115(2):E283-E291.