Innate immunity [259]
Régis Tournebize
Photonic BioImaging (UTechS PBI)
Thierry Pedron
Nathalie Sauvonnet
Biomaterials and Microfluidics
Intracellular traffic and cell compartmentalization Eukaryotic cells contain extensive internal membranes defining many compartments having each specific functions. However these organelles are constantly moving and reshaping, still retaining their identity. The maintenance of cell […]
Timothée Bruel
Antiviral Activities of Antibodies
Since the beginning of my career, my goal has been to understand the mechanisms of effector immune responses to viruses and the related viral countermeasures. During my thesis, I studied the origin of type […]
Yongzheng Wu
Cellular Biology of Microbial Infection
My interest is to investigate the pathogenesis of infectious diseases induced by bacteria in respiratory and reproductive systems. Particularly, I focus on pathogen-host interaction and try to understand the mechanisms by which host responses […]
Gérald Spaeth
U1201 – Genetic and molecular basis of host-parasite interactions
Dr. Gerald Späth currently holds a Research Director position at the Institut Pasteur in Paris, where he directs the Unit ‘Parasitologie moléculaire et Signalisation’ (12 members) and the Department ‘Parasites and Insect Vectors’ (ca. […]
Najma Rachidi
Signalling and host-parasite interactions
Dr. Najma Rachidi is a senior Researcher and the leader of the molecular parasitology team in the PARSIG unit. Her team investigates Host-pathogen interactions to (i) understand how Leishmania survives in immune cells, which […]
Muhamed-Kheir Taha
Invasive Bacterial Infections
Nolwenn Jouvenet
Virus sensing and signaling
We are exploring interactions between flaviviruses (Yellow fever, Dengue, Zika and West Nile viruses) and their mammalian and arthropod-hosts. On-going projects focus on deciphering mechanisms underlying virus-induced innate immunity and inflammation, using biochemical, virological […]
Anastasia V. Komarova
Institut Pasteur-Oncovita joint laboratory
Virus-host ribonucleoprotein complexes and innate immunity The RIG-I-like receptors (RLRs) play a major role in sensing intracytoplasmic RNA virus infection to initiate and modulate antiviral immunity. These RNA helicases interact with particular signatures of […]