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  • 2025
    Jean Contreras, Sophie Vichier-Guerre, Laurence Dugué, Frédéric Bonhomme, Corinne Jallet, Minh-Ha Nguyen, Bruno Vitorge, Alessandra Feoli, Gianluca Sbardella, J. I. Guijarro, Paola B Arimondo, In Quest of Chemical Probes for DNA Methylation Reader Proteins: Nucleoside and Dimer Analogues of 5‐Methylcytosine Interact with MBD2, Angewandte Chemie International Edition, In press, pp.e202425599. ⟨10.1002/anie.202425599⟩.
  • 2025
    Dejoux A, Zhu Q, Woolfe A, Godon O, Ellouze S, Mottet G, Castrillon C, Gillis C, Pecalvel C, Ganneau C, Iannascoli B, Lemoine F, Saul F, England P, Reber LL, Gouel-Chéron A, de Chaisemartin L, Haouz A, Millot GA, Bay S, Gérard A, Jönsson F, Chollet-Martin S, Bruhns P, Antibody-secreting cell repertoires hold high-affinity anti-rocuronium specificities that can induce anaphylaxis in vivo., J Allergy Clin Immunol 2025 Jan; (): .
  • 2025
    Pierre Nicolas Bizat, Nazarii Sabat*, Marcel Hollenstein*, Recent Advances in Biocatalytic and Chemoenzymatic Synthesis of Oligonucleotides, ChemBioChem. 2025, 26, e202400987.
  • 2025
    Grossi V, Cuny P, Militon C, Witwinowski J, Eddhif B, Sylvi L, Nowakowski M, Kosta A, Antheaume I, Cornil J, Dubrac S, Kende J, Gribaldo S, Borrel G, Halophilic archaea produce wax esters and use an alternative fatty acyl-coenzyme A reductase for precursor synthesis., ISME J 2025 Jan; 19(1): .
  • 2024
    Lara Johanna Friedrich, Axel Guthart, Min Zhou, Paola B. Arimondo, Thomas Efferth and Mona Dawood, Supercomputer-based virtual screening for DNMT1 inhibitors as novel anticancer agents, Int. J. Mol. Sci..
  • 2024
    Sabat N, Stämpfli A, Hanlon S, Bisagni S, Sladojevich F, Püntener K, Hollenstein M, Template-dependent DNA ligation for the synthesis of modified oligonucleotides., Nat Commun 2024 Sep; 15(1): 8009.
  • 2024
    Dejoux A, Zhu Q, Ganneau C, Goff OR, Godon O, Lemaitre J, Relouzat F, Huetz F, Sokal A, Vandenberghe A, Pecalvel C, Hunault L, Derenne T, Gillis CM, Iannascoli B, Wang Y, Rose T, Mertens C, Nicaise-Roland P, , England P, Mahévas M, de Chaisemartin L, Le Grand R, Letscher H, Saul F, Pissis C, Haouz A, Reber LL, Chappert P, Jönsson F, Ebo DG, Millot GA, Bay S, Chollet-Martin S, Gouel-Chéron A, Bruhns P, Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models., Sci Transl Med 2024 Sep; 16(764): eado4463.
  • 2024
    Fruchard Louna, Babosan Anamaria, Carvalho Andre, Lang Manon, Li Blaise, Duchateau Magalie, Giai-Gianetto Quentin, Matondo Mariette, Bonhomme Frédéric, Hatin Isabelle, Arbes Hugo, Fabret Céline, Sanchez Guillaume, Marchand Virginie, Motorin Yuri, Namy Olivier, de Crécy-Lagard Valérie, Mazel Didier, Baharoglu Zeynep, Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated to queuosine tRNA modification, Elife.
  • 2024
    Mistretta M, Cimino M, Campagne P, Volant S, Kornobis E, Hebert O, Rochais C, Dallemagne P, Lecoutey C, Tisnerat C, Lepailleur A, Ayotte Y, LaPlante SR, Gangneux N, Záhorszká M, Korduláková J, Vichier-Guerre S, Bonhomme F, Pokorny L, Albert M, Tinevez JY, Manina G, Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy., Nat Commun 2024 May; 15(1): 4175.
  • 2024
    , Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy, Nature Communications.
  • 2024
    Alexandra Fillion , Sophie Vichier-Guerre, Paola Barbara Arimondo, Adenine, a key player in biology and medicinal chemistry , Comptes Rendus Chimie, Académie des Sciences .
  • 2024
    Yamaguchi K, Chen X, Rodgers B, Miura F, Bashtrykov P, Bonhomme F, Salinas-Luypaert C, Haxholli D, Gutekunst N, Aygenli BÖ, Ferry L, Kirsh O, Laisné M, Scelfo A, Ugur E, Arimondo PB, Leonhardt H, Kanemaki MT, Bartke T, Fachinetti D, Jeltsch A, Ito T, Defossez PA. , Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells, Nature Communications.
  • 2024
    Scelfo A, Barra V, Abdennur N, Spracklin G, Busato F, Salinas-Luypaert C, Bonaiti E, Velasco G, Bonhomme F, Chipont A, Tijhuis AE, Spierings DCJ, Guérin C, Arimondo P, Francastel C, Foijer F, Tost J, Mirny L, Fachinetti D, Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization., J Cell Biol 2024 Apr; 223(4): .
  • 2024
    Andrea Scelfo, Viviana Barra, Nezar Abdennur, George Spracklin, Florence Busato, Catalina Salinas Luypaert, Elena Bonaiti, Guillaume Velasco, Frédéric Bonhomme, Anna Chipont, Andréa Tijhuis, Diana Spierings, Coralie Guerin, Paola B Arimondo, Claire Francastel, Floris Foijer, Jörg Tost, Leonid Mirny, and Daniele Fachinetti. , Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization, J Cell Biol.
  • 2023
    Canat A, Veillet A, Batrin R, Dubourg C, Lhoumaud P, Arnau-Romero P, Greenberg MVC, Bonhomme F, Arimondo PB, Illingworth R, Fabre E, Therizols P. , DAXX safeguards heterochromatin formation in embryonic stem cells, Journal Of Cell Science.
  • 2023
    Collados Rodríguez M, Maillard P, Journeaux A, Komarova AV, Najburg V, David RS, Helynck O, Guo M, Zhong J, Baize S, Tangy F, Jacob Y, Munier-Lehmann H, Meurs EF, Novel Antiviral Molecules against Ebola Virus Infection., Int J Mol Sci 2023 Sep; 24(19): .
  • 2023
    Antoine Canat, Adeline Veillet, Renaud Batrin, Clara Dubourg, Priscillia Lhoumaud, Pol Arnau-Romero, Maxim V C Greenberg, Frédéric Bonhomme, Paola B Arimondo, Robert Illingworth, Emmanuelle Fabre, Pierre Therizols, DAXX safeguards heterochromatin formation in embryonic stem cells, J Cell Sci. 2023 Sep 1:jcs.261092. doi: 10.1242/jcs.261092. Epub ahead of print. PMID: 37655670..
  • 2023
    Yakhou L, Azogui A, Gupta N, Albert JR, Miura F, Ferry L, Yamaguchi K, Battault S, Therizols P, Bonhomme F, Bethuel E, Sarkar A, Greenberg MVC, Arimondo PB, Cristofari G, Kirsh O, Ito T, Defossez PA, A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation, Nucleic Acids Res. 2023 Aug 31.
  • 2023
    Yakhou L, Azogui A, Gupta N, Albert JR, Miura F, Ferry L, Yamaguchi K, Battault S, Therizols P, Bonhomme F, Bethuel E, Sarkar A, Greenberg MVC, Arimondo PB, Cristofari G, Kirsh O, Ito T, Defossez PA, A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation, Nucleic Acids Research.
  • 2023
    Paola B. Arimondo, Sebastian Essig, Ulrich Schopfer, Arne Rufer, Advances in Chemical Probing Concepts for Chemical Biology applications, Chembiochem.
  • 2023
    Gupta N, Yakhou L, Albert JR, Azogui A, Ferry L, Kirsh O, Miura F, Battault S, Yamaguchi K, Laisné M, Domrane C, Bonhomme F, Sarkar A, Delagrange M, Ducos B, Cristofari G, Ito T, Greenberg MVC, Defossez PA, A genome-wide screen reveals new regulators of the 2-cell-like cell state, Nat Struct Mol Biol 30, 1105–1118 (2023).
  • 2023
    Gupta N, Yakhou L, Albert JR, Azogui A, Ferry L, Kirsh O, Miura F, Battault S, Yamaguchi K, Laisné M, Domrane C, Bonhomme F, Sarkar A, Delagrange M, Ducos B, Cristofari G, Ito T, Greenberg MVC, Defossez PA., A genome-wide screenreveals new regulators of the 2-cell-like cell state, Nat Struct Mol Biol.
  • 2023
    Gedeon A, Ayoub N, Brûlé S, Raynal B, Karimova G, Gelin M, Mechaly A, Haouz A, Labesse G, Munier-Lehmann H, Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMPDHs., Protein Sci 2023 Jun; (): e4703.
  • 2023
    Dobrescu I, Hammam E, Dziekan JM, Claës A, Halby L, Preiser P, Bozdech Z, Arimondo PB, Scherf A, Nardella F, Plasmodium falciparum Eukaryotic Translation Initiation Factor 3 is Stabilized by Quinazoline-Quinoline Bisubstrate Inhibitors., ACS Infect Dis 2023 May; (): .
  • 2023
    Cawez F, Mercuri PS, Morales-Yãnez FJ, Maalouf R, Vandevenne M, Kerff F, Guérin V, Mainil J, Thiry D, Saulmont M, Vanderplasschen A, Lafaye P, Aymé G, Bogaerts P, Dumoulin M, Galleni M. , Development of Nanobodies as Theranostic Agents against CMY-2-Like Class C β-Lactamases., Antimicrob Agents Chemother. .
  • 2023
    Nardella F, Dobrescu I, Hassan H, Rodrigues F, Thiberge S, Mancio-Silva L, Tafit A, Jallet C, Cadet-Daniel V, Goussin S, Lorthiois A, Menon Y, Molinier N, Pechalrieu D, Long C, Sautel F, Matondo M, Duchateau M, Médard G, Witkowski B, Scherf A, Halby L, Arimondo PB, Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum., iScience 2023 Feb; 26(2): 105940.
  • 2023
    Gedeon A, Karimova G, Ayoub N, Dairou J, Giai Gianetto Q, Vichier-Guerre S, Vidalain PO, Ladant D, Munier-Lehmann H, Interaction network among de novo purine nucleotide biosynthesis enzymes in Escherichia coli., FEBS J 2023 Feb; (): .
  • 2023
    Auberson, Y.P., Arimondo, P.B., Duca, M., Essig, S., Grether, U., Rufer, A.C., Sbardella, G., Schopfer, U., Torrens, A., van der Stelt, M., Vauzeilles, B., Vázquez, O. and Zhang, A.X., EFMC: Trends in Medicinal Chemistry and Chemical Biology, Chemistry Europe.
  • 2023
    Clément DA, Gelin M, Leseigneur C, Huteau V, Mondange L, Pons JL, Dussurget O, Lionne C, Labesse G, Pochet S, , Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria., Eur J Med Chem 2023 Jan; 246(): 114941.
  • 2023
    Sabat N, Katkevica D, Pajuste K, Flamme M, Stämpfli A, Katkevics M, Hanlon S, Bisagni S, Püntener K, Sladojevich F, Hollenstein M*, Towards the controlled enzymatic synthesis of LNA containing oligonucleotides., Front Chem 2023 ; 11(): 1161462.
  • 2022
    Chiara Figazzolo, Frédéric Bonhomme, Saidbakhrom Saidjalolov, Mélanie Ethève-Quelquejeu, and Marcel Hollenstein*, Enzymatic Synthesis of Vancomycin-Modified DNA, Molecules 2022, 27, 8927.
  • 2022
    Carrier A, Desjobert C, Lobjois V, Rigal L, Busato F, Tost J, Ensenyat-Mendez M., Marzese D.M., Pradines A. Favre G, Lamant, L, Lanfrancone L, Etievant C, Arimondo PB, Riond J, Epigenetically regulated PCDHB15 impairs aggressiveness of metastatic melanoma cells, Clinical Epigenetics 2022 14, 156 .
  • 2022
    Carrier A, Desjobert C, Ponger L, Lamant L, Bustos M, Torres-Ferreira J, Henrique R, Jeronimo C, Lanfrancone L, Delmas A, Favre G, Delaunay A, Busato F, Hoon DSB, Tost J, Etievant C, Riond J, Arimondo PB, , DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness., Elife 2022 Sep; 11(): .
  • 2022
    Rahimova R, Nogaret P, Huteau V, Gelin M, Clément DA, Labesse G, Pochet S, Blanc-Potard AB, Lionne C, , Structure-based design, synthesis and biological evaluation of a NAD+ analogue targeting Pseudomonas aeruginosa NAD kinase., FEBS J 2022 Aug; (): .
  • 2022
    Flamme, M.; Katkevica, D.; Pajuste, K.; Katkevics, M.; Sabat, N.; Hanlon, S.; Marzuoli, I.; Püntener, K.; Sladojevich, F.; Hollenstein, M., Benzoyl and pivaloyl as efficient protecting groups for controlled enzymatic synthesis of DNA and XNA oligonucleotides, Asian J. Org. Chem. 2022, e202200384.
  • 2022
    A. Carrier, C. Desjobert, L. Ponger, L. Lamant, M. Bustos, J. Torres-Ferreira, R. Henrique, C. Jeronimo, L. Lanfrancone, A. Delmas, G. Favre, A. Daunay, F. Busato, D.S.B. Hoon, J. Tost, C. Etievant, J. Riond, P.B. Arimondo, , DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness, https://biorxiv.org/cgi/content/short/2022.04.11.487909v1.
  • 2022
    Flamme M, Hanlon S, Marzuoli I, Püntener K, Sladojevich F, Hollenstein M, Evaluation of 3′-phosphate as a transient protecting group for controlled enzymatic synthesis of DNA and XNA oligonucleotides., Commun Chem 2022 Jun; 5(1): 68.
  • 2022
    Sabat, N.; Zhou, W.; Gandon, V.; Guinchard, X.; Vincent, G., Unbiased C3-Electrophilic Indoles: Triflic Acid Mediated C3-Regioselective Hydroarylation of N-H Indoles, Angew. Chem. Int. Ed. 2022, 61, e2022044.
  • 2022
    Chen KY, Krischuns T, Varga LO, Harigua-Souiai E, Paisant S, Zettor A, Chiaravalli J, Delpal A, Courtney D, O'Brien A, Baker SC, Decroly E, Isel C, Agou F, Jacob Y, Blondel A, Naffakh N, , A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors., Antiviral Res 2022 May; 201(): 105272.
  • 2022
    Si Y, Bon C, Barbachowska M, Cadet-Daniel V, Jallet C, Soresinetti L, Boullé M, Duchateau M, Matondo M, Agou F, Halby L, Arimondo PB, , A novel screening strategy to identify histone methyltransferase inhibitors reveals a crosstalk between DOT1L and CARM1., RSC Chem Biol 2022 Apr; 3(4): 456-467.
  • 2022
    Zhang, Z.; Sabat, N.; Frison, G.; Marinetti, A.; Guinchard, X., Enantioselective Au(I)-Catalyzed Multicomponent Annulation via Tethered Counterion-Directed Catalysis, ACS Catal. 2022, 12, 4046 - 4053.
  • 2022
    Sabat, N.; Ouarti, A.; Migianu-Griffoni, E.; Lecouvey, M.; Ferraris, O.; Gallier, F.; Peyrefitte, C.; Lubin-Germain, N.; Uziel, J., Synthesis, antiviral and antitumor activities investigations of a series of Ribavirin C-nucleoside analogue prodrugs, Bioorg. Chem. 2022, 122, 105723.
  • 2022
    Soualmia, F.; Guillot, A.; Sabat, N.; Brewee, C.; Haumann, M.; Guinchard, X.; Benjdia, A.; Berteau, O., Biochemical and XAS investigation of TsrM, a B12-dependent Radical SAM Enzyme Catalyzing Non-radical reaction, Chem. Eur. J. 2022, 28, e2022006.
  • 2022
    Walter P, Mechaly A, Bous J, Haouz A, England P, Lai-Kee-Him J, Ancelin A, Hoos S, Baron B, Trapani S, Bron P, Labesse G, Munier-Lehmann H, , Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target., FEBS J 2022 Feb; (): .
  • 2021
    Song L, Merceron R, Hulpia F, Lucía A, Gracia B, Jian Y, Risseeuw MDP, Verstraelen T, Cos P, Aínsa JA, Boshoff HI, Munier-Lehmann H, Savvides SN, Van Calenbergh S, , Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors., Eur J Med Chem 2021 Dec; 225(): 113784.
  • 2021
    Bon C, Arimondo PB, Halby L, , Direct Synthesis of Allyl Amines with 2-Nitrosulfonamide Derivatives via the Tsuji-Trost Reaction., ChemistryOpen 2021 12; 10(12): 1166-1169.
  • 2021
    Elie Hammam, Ameya Sinha, Sebastian Baumgarten, Flore Nardella, Jiaqi Liang, Samia Miled, Frédéric Bonhomme, Diane Erdmann, Benoit Arcangioli, Paola B. Arimondo, Peter Dedon, Peter Preiser, Artur Scherf, Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation, mBio. 2021 Nov-Dec; 12(6): e02558-21.
  • 2021
    Luviano N, Lopez M, Gawehns F, Chaparro C, Arimondo PB, Ivanovic S, David P, Verhoeven K, Cosseau C, Grunau C, , The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor., Epigenetics Chromatin 2021 10; 14(1): 48.
  • 2021
    Anca F. Savulescu, Robyn Brackin, Emmanuel Bouilhol, Benjamin Dartigues, Jonathan H. Warrell, Mafalda R. Pimentel, Nicolas Beaume, Isabela C. Fortunato, Stephane Dallongeville, Mikaël Boullé, Hayssam Soueidan, Fabrice Agou, Jan Schmoranzer, Jean-Christophe Olivo-Marin, Claudio A. Franco, Edgar R. Gomes, Macha Nikolski, and Musa M. Mhlanga , Interrogating RNA and protein spatial subcellular distribution in smFISH data with DypFISH, Volume 1, Issue 5, 27 September 2021, 100068.
  • 2021
    Meyer B, Chiaravalli J, Gellenoncourt S, Brownridge P, Bryne DP, Daly LA, Grauslys A, Walter M, Agou F, Chakrabarti LA, Craik CS, Eyers CE, Eyers PA, Gambin Y, Jones AR, Sierecki E, Verdin E, Vignuzzi M, Emmott E, , Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential., Nat Commun 2021 09; 12(1): 5553.
  • 2021
    Hosseiniporgham S, Biet F, Ganneau C, Bannantine JP, Bay S, Sechi LA, , A Comparative Study on the Efficiency of Two Mycobacterium avium subsp. paratuberculosis (MAP)-Derived Lipopeptides of L3P and L5P as Capture Antigens in an In-House Milk ELISA Test., Vaccines (Basel) 2021 Sep; 9(9): .
  • 2021
    Zahradník J, Marciano S, Shemesh M, Zoler E, Harari D, Chiaravalli J, Meyer B, Rudich Y, Li C, Marton I, Dym O, Elad N, Lewis MG, Andersen H, Gagne M, Seder RA, Douek DC, Schreiber G, , SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution., Nat Microbiol 2021 09; 6(9): 1188-1198.
  • 2021
    , Towards the sustainable discovery and development of new antibiotics, Nat Rev Chem. 2021 Aug 19:1-24.
  • 2021
    Bon C, Si, Y, Pernak M, Barbachowska, M, Levi-Acobas, E, Cadet Daniel, V, Jallet C, Ruzic D, Djokovic N, Djikić T., Nikolic K, Halby L, Arimondo PB, Synthesis and Biological Activity of a Cytostatic Inhibitor of MLLr Leukemia Targeting the DOT1L Protein, Molecules 2021, 26(17), 5300 .
  • 2021
    Czernecki D, Bonhomme F, Kaminski PA, Delarue M , Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA., Nat Commun 2021 08; 12(1): 4710.
  • 2021
    Czernecki D., Bonhomme F., Kaminski PA. and Delarue M., Characterization of a triad of genes in cyanophage S-2Lsufficient to replace adenine by 2-aminoadenine in bacterial DNA, NATURE.
  • 2021
    Lavigne M, Helynck O, Rigolet P, Boudria-Souilah R, Nowakowski M, Baron B, Brülé S, Hoos S, Raynal B, Guittat L, Beauvineau C, Petres S, Granzhan A, Guillon J, Pratviel G, Teulade-Fichou MP, England P, Mergny JL, Munier-Lehmann H, SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction., Nucleic Acids Res 2021 Jul; 49(13): 7695-7712.
  • 2021
    , Multigram synthesis of an orthogonally-protected pentasaccharide for use as a glycan precursor in a Shigella flexneri 3a conjugate vaccine: application to a ready-for-conjugation decasaccharide, Org. Chem. Front..
  • 2021
    Cohen D, Atsmon J, Artaud C, Meron-Sudai S, Gougeon ML, Bialik A, Goren S, Asato V, Ariel-Cohen O, Reizis A, Dorman A, Hoitink CWG, Westdijk J, Ashkenazi S, Sansonetti P, Mulard LA, Phalipon A, , Safety and immunogenicity of a synthetic carbohydrate conjugate vaccine against Shigella flexneri 2a in healthy adult volunteers: a phase 1, dose-escalating, single-blind, randomised, placebo-controlled study., Lancet Infect Dis 2021 04; 21(4): 546-558.
  • 2021
    Dhara D, Mulard LA, , Exploratory N-Protecting Group Manipulation for the Total Synthesis of Zwitterionic Shigella sonnei Oligosaccharides., Chemistry 2021 Mar; 27(18): 5694-5711.
  • 2021
    Hu Z, Benkoulouche M, Barel LA, Le Heiget G, Ben Imeddourene A, Le Guen Y, Monties N, Guerreiro C, Remaud-Siméon M, Moulis C, André I, Mulard LA, , Convergent Chemoenzymatic Strategy to Deliver a Diversity of Shigella flexneri Serotype-Specific O-Antigen Segments from a Unique Lightly Protected Tetrasaccharide Core., J Org Chem 2021 02; 86(3): 2058-2075.
  • 2021
    Benkoulouche M, Ben Imeddourene A, Barel LA, Le Heiget G, Pizzut S, Kulyk H, Bellvert F, Bozonnet S, Mulard LA, Remaud-Siméon M, Moulis C, André I, , Redirecting substrate regioselectivity using engineered ΔN123-GBD-CD2 branching sucrases for the production of pentasaccharide repeating units of S. flexneri 3a, 4a and 4b haptens., Sci Rep 2021 01; 11(1): 2474.
  • 2021
    Gagnot G, Hervin V, Coutant EP, Goyard S, Jacob Y, Rose T, Hibti FE, Quatela A, Janin YL, , Core-Modified Coelenterazine Luciferin Analogues: Synthesis and Chemiluminescence Properties., Chemistry 2021 Jan; 27(6): 2112-2123.
  • 2021
    Jian Y, Forbes HE, Hulpia F, Risseeuw MDP, Caljon G, Munier-Lehmann H, Boshoff HIM, Van Calenbergh S, , 2-((3,5-Dinitrobenzyl)thio)quinazolinones: Potent Antimycobacterial Agents Activated by Deazaflavin (F420)-Dependent Nitroreductase (Ddn)., J Med Chem 2021 01; 64(1): 440-457.
  • 2021
    Fernandez J, Hassen-Khodja C, Georget V, Rose T, Jacob Y, Janin YL, Nisole S, Vidalain PO, Arhel NJ, , Measuring the subcellular compartmentalization of viral infections by protein complementation assay., Proc Natl Acad Sci U S A 2021 01; 118(2): .
  • 2021
    Bay S, Begg D, Ganneau C, Branger M, Cochard T, Bannantine JP, Köhler H, Moyen JL, Whittington RJ, Biet F, , Engineering Synthetic Lipopeptide Antigen for Specific Detection of Mycobacterium avium subsp. paratuberculosis Infection., Front Vet Sci 2021 ; 8(): 637841.
  • 2021
    Köhler H, Liebler-Tenorio E, Hughes V, Stevenson K, Bakker D, Willemsen P, Bay S, Ganneau C, Biet F, Vordermeier HM, , Interferon-γ Response of Mycobacterium avium subsp. paratuberculosis Infected Goats to Recombinant and Synthetic Mycobacterial Antigens., Front Vet Sci 2021 ; 8(): 645251.
  • 2020
    Jian Y, Merceron R, De Munck S, Forbes HE, Hulpia F, Risseeuw MDP, Van Hecke K, Savvides SN, Munier-Lehmann H, Boshoff HIM, Van Calenbergh S, , Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents., Eur J Med Chem 2020 Nov; 206(): 112659.
  • 2020
    Goyard S, Balbino B, Chinthrajah RS, Lyu SC, Janin YL, Bruhns P, Poncet P, Galli SJ, Nadeau KC, Reber LL, Rose T, , A highly sensitive bioluminescent method for measuring allergen-specific IgE in microliter samples., Allergy 2020 11; 75(11): 2952-2956.
  • 2020
    Clément DA, Leseigneur C, Gelin M, Coelho D, Huteau V, Lionne C, Labesse G, Dussurget O, Pochet S, , New Chemical Probe Targeting Bacterial NAD Kinase., Molecules 2020 Oct; 25(21): .
  • 2020
    Thieulent C, Hue E, Sutton G, Fortier C, Dallemagne P, Zientara S, Munier-Lehmann H, Hans A, Paillot R, Vidalain PO, Pronost S, , Identification of antiviral compounds against equid herpesvirus-1 using real-time cell assay screening: efficacy of decitabine and valganciclovir alone or in combination., Antiviral Res. 2020 Sep; (): 104931.
  • 2020
    Jian Y, Hulpia F, Risseeuw MDP, Forbes HE, Munier-Lehmann H, Caljon G, Boshoff HIM, Van Calenbergh S, , Synthesis and structure activity relationships of cyanopyridone based anti-tuberculosis agents., Eur J Med Chem 2020 Sep; 201(): 112450.
  • 2020
    Bon C, Halby L, Arimondo PB, , Bisubstrate inhibitors: the promise of a selective and potent chemical inhibition of epigenetic ‘writers’., Epigenomics 2020 09; 12(17): 1479-1482.
  • 2020
    Milcendeau, P.; Sabat, N.; Ferry, A.; Guinchard, X., Gold-Catalyzed Enantioselective Functionalizations of Indoles, Org. Biomol. Chem. 2020, 18, 6006 – 6017.
  • 2020
    Topart C, Werner E, Arimondo PB, , Wandering along the epigenetic timeline., Clin Epigenetics 2020 07; 12(1): 97.
  • 2020
    Valle-Casuso JC, Gaudaire D, Martin-Faivre L, Madeline A, Dallemagne P, Pronost S, Munier-Lehmann H, Zientara S, Vidalain PO, Hans A, , Replication of Equine arteritis virus is efficiently suppressed by purine and pyrimidine biosynthesis inhibitors., Sci Rep 2020 Jun; 10(1): 10100.
  • 2020
    Jian Y, Hulpia F, D P Risseeuw M, Forbes HE, Caljon G, Munier-Lehmann H, I M Boshoff H, Van Calenbergh S, , 1-(1-Arylethylpiperidin-4-yl)thymine Analogs as Antimycobacterial TMPK Inhibitors., Molecules 2020 Jun; 25(12): .
  • 2020
    Encarnação JC, Napolitano V, Opassi G, Danielson UH, Dubin G, Popowicz GM, Munier-Lehmann H, Buijs J, Andersson K, Björkelund H, , A real-time cell-binding assay reveals dynamic features of STxB-Gb3 cointernalization and STxB-mediated cargo delivery into cancer cells., FEBS Lett. 2020 May; (): .
  • 2020
    Sabat, N.; Soualmia, F.; Retailleau, P.; Bendjdia, A.; Berteau, O.; Guinchard, X., Gold-Catalyzed Spirocyclization Reactions of N-propargyl Tryptamines and Tryptophanes in Aqueous Media, Org. Lett. 2020, 22, 4344 – 4349.
  • 2020
    Rosenbaum P, Artaud C, Bay S, Ganneau C, Campone M, Delaloge S, Gourmelon C, Loirat D, Medioni J, Pein F, Sablin MP, Tredan O, Varga A, Leclerc C, , The fully synthetic glycopeptide MAG-Tn3 therapeutic vaccine induces tumor-specific cytotoxic antibodies in breast cancer patients., Cancer Immunol Immunother 2020 May; 69(5): 703-716.
  • 2020
    Olivier Borkowski, Mathilde Koch, Agnès Zettor, Amir Pandi, Angelo Cardoso Batista, Paul Soudier, Jean-Loup Faulon, Large Scale Active-Learning-Guided Exploration for in Vitro Protein Production Optimization, Nat Commun. 2020 Apr 20;11(1):1872.
  • 2020
    Pechalrieu D, Assemat F, Halby L, Marcellin M, Yan P, Chaoui K, Sharma S, Chiosis G, Burlet-Schiltz O, Arimondo PB, Lopez M, , Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs., ACS Chem Biol 2020 04; 15(4): 952-961.
  • 2020
    Gelin M, Paoletti J, Nahori MA, Huteau V, Leseigneur C, Jouvion G, Dugué L, Clément D, Pons JL, Assairi L, Pochet S, Labesse G, Dussurget O, , From Substrate to Fragments to Inhibitor Active In Vivo against Staphylococcus aureus., ACS Infect Dis 2020 Mar; 6(3): 422-435.
  • 2020
    Nardella F, Halby L, Hammam E, Erdmann D, Cadet-Daniel V, Peronet R, Ménard D, Witkowski B, Mecheri S, Scherf A, Arimondo PB, , DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites., ACS Cent Sci 2020 Jan; 6(1): 16-21.
  • 2020
    Vichier-Guerre S, Ku T, Pochet S, Seley-Radtke KL, An expedient synthesis of flexible nucleosides through enzymatic glycosylation of proximal and distal fleximer bases, Chembiochem 2020 Jan;.
  • 2019
    Sabat, N.; Migianu-Griffoni, E.; Tudela, T.; Lecouvey, M.; Kellouche, S.; Carreiras, F.; Gallier, F.; Uziel, J.; Lubin-Germain, N., Synthesis and antitumor activities investigation of a C-nucleoside analogue of ribavirin, Eur. J. Med. Chem. 2020, 188, 112009.
  • 2019
    Vigne J, Bay S, Aid-Launais R, Pariscoat G, Rucher G, Sénémaud J, Truffier A, Anizan N, Even G, Ganneau C, Andreata F, Le Borgne M, Nicoletti A, Le Guludec D, Caligiuri G, Rouzet F, , Cleaved CD31 as a target for in vivo molecular imaging of inflammation., Sci Rep 2019 Dec; 9(1): 19560.
  • 2019
    Jian Y, Risseeuw MDP, Froeyen M, Song L, Cappoen D, Cos P, Munier-Lehmann H, van Calenbergh S, , 1-(Piperidin-3-yl)thymine amides as inhibitors of M. tuberculosis thymidylate kinase., J Enzyme Inhib Med Chem 2019 Dec; 34(1): 1730-1739.
  • 2019
    Bon C, Erdmann D, Halby L, Arimondo PB, , [Chemical targeting of DNA and histone methylation in cancer: Novelties, hopes and promises]., Bull Cancer 2019 Oct; 106(10): 823-833.
  • 2019
    Said Halidi KN, Fontan E, Boucharlat A, Davignon L, Charpentier M, Boullé M, Weil R, Israël A, Laplantine E, Agou F., Two NEMO-like Ubiquitin-Binding Domains in CEP55 Differently Regulate Cytokinesis., iScience. 2019 Sep 25;20:292-309.
  • 2019
    M. M. Pichon, D. Hazelard, P. Compain, Metal-Free Deoxygenation of α-Hydroxy Carbonyl Compounds and Beyond, Eur JOC, 2019, 37, 6320-6332.
  • 2019
    Friederike Jönsson*, Luc de Chaisemartin*, Vanessa Granger†, Aurélie Gouel-Chéron†, Caitlin M. Gillis, Qianqian Zhu, Fadia Dib, Pascale Nicaise-Roland, Christelle Ganneau, Maria Hurtado-Nedelec, Catherine Paugam-Burtz, Skander Necib, Hawa Keita-Meyer, Matthieu Le Dorze, Bernard Cholley, Olivier Langeron, Laurent Jacob, Benoit Plaud, Marc Fischler, Caroline Sauvan, Marie-Thérèse Guinnepain, Philippe Montravers, Michel Aubier, Sylvie Bay, Catherine Neukirch, Florence Tubach‡, Dan Longrois‡, Sylvie Chollet-Martin‡,§ and Pierre Bruhns‡,§ , An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis, Sci Transl Med. 2019 Jul 10: Vol. 11, Issue 500, eaat1479 DOI: 10.1126/scitranslmed.aat1479 .
  • 2019
    Reolon LW, Vichier-Guerre S, de Matos BM, Dugué L, Assunção TRDS, Zanchin NIT, Pochet S, Guimarães BG, Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4, Nucleic Acids Res. 2019 Jun;47(11):5973-5987.
  • 2019
    Arimondo PB, Barberousse A, Pontarotti G, , The Many Faces of EpigeneticsOxford, December 2017., Epigenetics 2019 06; 14(6): 623-631.
  • 2019
    M. M. Pichon, F. Stauffert, A. Bodlenner, P. Compain, Tight-binding inhibition of jack bean α-mannosidase by glycoimidazole clusters, Org. Biomol. Chem., 2019, 17, 5801-5817.
  • 2019
    Alexandre T, Lupan A, Helynck O, Vichier-Guerre S, Dugué L, Gelin M, Haouz A, Labesse G, Munier-Lehmann H, First-in-class allosteric inhibitors of bacterial IMPDHs, Eur J Med Chem 2019 Feb;167:124-132.
  • 2019
    Vichier-Guerre S, Dugué L, Pochet S, 2′-Deoxyribonucleoside 5′-triphosphates bearing 4-phenyl and 4-pyrimidinyl imidazoles as DNA polymerase substrates, Org. Biomol. Chem. 2019 01;17(2):290-301.
  • 2019
    Thieulent CJ, Hue ES, Fortier CI, Dallemagne P, Zientara S, Munier-Lehmann H, Hans A, Fortier GD, Pitel PH, Vidalain PO, Pronost SL, Screening and evaluation of antiviral compounds against Equid alpha-herpesviruses using an impedance-based cellular assay, Virology 2019 01;526:105-116.
  • 2019
    Barel LA, Mulard LA, , Classical and novel strategies to develop a Shigella glycoconjugate vaccine: from concept to efficacy in human., Hum Vaccin Immunother 2019 ; 15(6): 1338-1356.
  • 2018
    García-Weber D, Dangeard AS, Cornil J, Thai L, Rytter H, Zamyatina A, Mulard LA, Arrieumerlou C, , ADP-heptose is a newly identified pathogen-associated molecular pattern of Shigella flexneri., EMBO Rep 2018 12; 19(12): .
  • 2018
    Kunstmann S, Scheidt T, Buchwald S, Helm A, Mulard LA, Fruth A, Barbirz S, , Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens., Viruses 2018 08; 10(8): .
  • 2018
    Laskaris P, Vicentefranqueira R, Helynck O, Jouvion G, Calera JA, du Merle L, Suzenet F, Buron F, de Sousa RA, Mansuy D, Cavaillon JM, Latgé JP, Munier-Lehmann H, Ibrahim-Granet O, A Novel Polyaminocarboxylate Compound To Treat Murine Pulmonary Aspergillosis by Interfering with Zinc Metabolism, Antimicrob. Agents Chemother. 2018 Jun;62(6).
  • 2018
    Sabat, N.; Poštová Slavětínská, L.; Klepetářová, B.; Hocek, M., C-H Imidation of 7-Deazapurines., ACS Omega. 2018, 3, 4674 – 4678.
  • 2018
    Charpentier M, Khedher AHY, Menoret S, Brion A, Lamribet K, Dardillac E, Boix C, Perrouault L, Tesson L, Geny S, De Cian A, Itier JM, Anegon I, Lopez B, Giovannangeli C and Concordet JP, CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair., Nat Commun. 2018 Mar 19;9(1):1133.
  • 2018
    Song L, Merceron R, Gracia B, Quintana AL, Risseeuw MDP, Hulpia F, Cos P, Aínsa JA, Munier-Lehmann H, Savvides SN, Van Calenbergh S, Structure Guided Lead Generation toward Nonchiral M. tuberculosis Thymidylate Kinase Inhibitors, J. Med. Chem. 2018 Apr;61(7):2753-2775.
  • 2018
    Vincenzo Di Donato, Flavia De Santis, Shahad Albadri, Thomas Oliver Auer, Karine Duroure, Marine Charpentier, Jean-Paul Concordet, Christoph Gebhardt, and Filippo Del Bene, An Attractive Reelin Gradient Establishes Synaptic Lamination in the Vertebrate Visual System, Neuron. 2018 Feb 5. pii: S0896-6273(18)30055-2..
  • 2018
    Valentine Mosbach, Lucie Poggi, David Viterbo, Marine Charpentier and Guy-Franck Richard, TALEN-Induced Double-Strand Break Repair of CTG Trinucleotide Repeats., Cell Rep. 2018 Feb 20;22(8):2146-2159.
  • 2018
    M. M. Pichon, F. Stauffert, L. G. Addante-Moya, A. Bodlenner, P. Compain, Metal-Free Iodine-Mediated Deoxygenation of Alcohols in the Position α to Electron-Withdrawing Groups, Eur. JOC, 2018, 13, 1538-1545.
  • 2018
    Harigua-Souiai E, Abdelkrim YZ, Bassoumi-Jamoussi I, Zakraoui O, Bouvier G, Essafi-Benkhadir K, Banroques J, Desdouits N, Munier-Lehmann H, Barhoumi M, Tanner NK, Nilges M, Blondel A, Guizani I, Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A, PLoS Negl Trop Dis 2018 01;12(1):e0006160.
  • 2018
    Suthagar K, Jiao W, Munier-Lehmann H, Fairbanks AJ, Synthesis of sulfamide analogues of deoxthymidine monophosphate as potential inhibitors of mycobacterial cell wall biosynthesis, Carbohydr. Res. 2018 Mar;457:32-40.
  • 2017
    Dabo S., Maillard P., Collados Rodriguez M., Hansen M. D., Mazouz S., Bigot D. J., Tible M., Janvier G., Helynck O., Cassonnet P., Jacob Y., Bellalou J., Gatignol A., Patel R. C., Hugon J., Munier-Lehmann H., Meurs E. F., Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT, Sci Rep. 2017 Nov 23;7(1):16129.
  • 2017
    Sabat, N.; Smolén. S.; Nauš, P.; Perlíková. P.; Cebová. M.; Poštová Slavětínská, L.; Hocek, M., Synthesis of 2,6-Substituted-7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted-5-(Het)aryl-pyrrolo[2,3-d]pyrimidines, Synthesis. 2017, 49, 4623 – 4650.
  • 2017
    D. Hazelard, M. L. Lepage, J. P. Schneider, M. M. Pichon, F. Massicot, P. Compain, Large Scale Synthesis of 2,3,4,6-Tetra-O-Benzyl-1-Deoxynojirimycin, Carbohydrates Chemistry: ProvenSyntheticMethods, Vol.4, 2017, 303-314.
  • 2017
    Buchieri MV, Cimino M, Rebollo-Ramirez S, Beauvineau C, Cascioferro A, Favre-Rochex S, Helynck O, Naud-Martin D, Larrouy-Maumus G, Munier-Lehmann H, Gicquel B, Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in Mycobacterium smegmatis, J. Med. Chem. 2017 Sep 14;60(17):7425-7433.
  • 2017
    Lucas-Hourani M, Dauzonne D, Munier-Lehmann H, Khiar S, Nisole S, Dairou J, Helynck O, Afonso PV, Tangy F, Vidalain PO, Original chemical series of pyrimidine biosynthesis inhibitors that boost the antiviral interferon response, Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00383-17.
  • 2017
    Li T, Vandesquille M, Bay S, Dhenain M, Delatour B, Lafaye P, , Selection of similar single domain antibodies from two immune VHH libraries obtained from two alpacas by using different selection methods., Immunol Lett 2017 Aug; 188(): 89-95.
  • 2017
    Bannantine JP, Etienne G, Laval F, Stabel JR, Lemassu A, Daffé M, Bayles DO, Ganneau C, Bonhomme F, Branger M, Cochard T, Bay S, Biet F, , Cell wall peptidolipids of Mycobacterium avium: from genetic prediction to exact structure of a nonribosomal peptide., Mol Microbiol 2017 Aug; 105(4): 525-539.
  • 2017
    Pancrace C, Jokela J, Sassoon N, Ganneau C, Desnos-Ollivier M, Wahlsten M, Humisto A, Calteau A, Bay S, Fewer DP, Sivonen K, Gugger M, Rearranged Biosynthetic Gene Cluster and Synthesis of Hassallidin E in Planktothrix serta PCC 8927, ACS Chem Biol 2017 Jul; 12(7): 1796-1804.
  • 2017
    Khiar S, Lucas-Hourani M, Nisole S, Smith N, Helynck O, Bourgine M, Ruffié C, Herbeuval JP, Munier-Lehmann H, Tangy F, Vidalain PO, Identification of a small molecule that primes the type I interferon response to cytosolic DNA, Sci Rep 2017 05;7(1):2561.
  • 2017
    Eckenfelder A, Ségéral E, Pinzón N, Ulveling D, Amadori C, Charpentier M, Nidelet S, Concordet JP, Zagury JF, Paillart JC, Berlioz-Torrent C, Seitz H, Emiliani S, Gallois-Montbrun S, Argonaute proteins regulate HIV-1 multiply spliced RNA and viral production in a Dicer independent manner, Nucleic Acids Res. 2017 Apr;45(7):4158-4173.
  • 2017
    Briard B, Rasoldier V, Bomme P, ElAouad N, Guerreiro C, Chassagne P, Muszkieta L, Latgé JP, Mulard L, Beauvais A, , Dirhamnolipids secreted from Pseudomonas aeruginosa modify anjpegungal susceptibility of Aspergillus fumigatus by inhibiting β1,3 glucan synthase activity., ISME J 2017 07; 11(7): 1578-1591.
  • 2017
    Koseki Y, Kanetaka H, Tsunosaki J, Munier-Lehmann H, Aoki S, Tetrahydro-2-furanyl-2,4(1H,3H)-pyrimidinedione derivatives as novel antibacterial compounds against Mycobacterium, Int. J. Mycobacteriol. 2017 Jan-Mar;6(1):61-69.
  • 2017
    Bal E, Laplantine E, Hamel Y, Dubosclard V, Boisson B, Pescatore A, Picard C, Hadj-Rabia S, Royer G, Steffann J, Bonnefont JP, Ursini VM, Vabres P, Munnich A, Casanova JL, Bodemer C, Weil R, Agou F, Smahi A, Lack of interaction between NEMO and SHARPIN impairs linear ubiquitination and NF-κB activation and leads to incontinentia pigmenti., J Allergy Clin Immunol. 2017 Dec;140(6):1671-1682.e2.
  • 2017
    Mahamed D, Boulle M, Ganga Y, Mc Arthur C, Skroch S, Oom L, Catinas O, Pillay K, Naicker M, Rampersad S, Mathonsi C, Hunter J, Wong EB, Suleman M, Sreejit G, Pym AS, Lustig G, Sigal A, Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells., Elife. 2017 May 5;6. pii: e28205.
  • 2017
    Phillips AF, Millet AR, Tigano M, Dubois SM, Crimmins H, Babin L, Charpentier M, Piganeau M, Brunet E, Sfeir A, Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion, Mol. Cell 2017 Feb;65(3):527-538.e6.
  • 2017
    Christelle Ganneau, Catherine Simenel, Emeline Emptas, Tiphanie Courtiol, Yves-Marie Coïc, Cécile Artaud, Edith Dériaud, Frédéric Bonhomme, Muriel Delepierre, Claude Leclerc, Richard Lo-Man and Sylvie Bay, Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate, Organic & Biomolecular Chemistry, 2017, 15, 114 - 123.
  • 2017
    Vandesquille M, Li T, Po C, Ganneau C, Lenormand P, Dudeffant C, Czech C, Grueninger F, Duyckaerts C, Delatour B, Dhenain M, Lafaye P, Bay S, , Chemically-defined camelid antibody bioconjugate for the magnetic resonance imaging of Alzheimer’s disease., MAbs 2017 ; 9(6): 1016-1027.
  • 2016
    Li T, Vandesquille M, Koukouli F, Dudeffant C, Youssef I, Lenormand P, Ganneau C, Maskos U, Czech C, Grueninger F, Duyckaerts C, Dhenain M, Bay S, Delatour B, Lafaye P, , Camelid single-domain antibodies: A versatile tool for in vivo imaging of extracellular and intracellular brain targets., J Control Release 2016 Dec; 243(): 1-10.
  • 2016
    Paoletti J, Assairi L, Gelin M, Huteau V, Nahori MA, Dussurget O, Labesse G, Pochet S, , 8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode., Eur J Med Chem 2016 Nov; 124(): 1041-1056.
  • 2016
    Boullé M, Müller TG, Dähling S, Ganga Y, Jackson L, Mahamed D, Oom L, Lustig G, Neher RA, Sigal A, HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell, PLoS Pathog. 2016 Nov 3;12(11):e1005964.
  • 2016
    Sabat, N.; Nauš, P.; Matyašovský, J.; Dziuba, D.; Poštová Slavetínská, L.; Hocek, M., Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions, Synthesis. 2016, 48, 1029 – 1045.
  • 2016
    Sabat N, Poštová Slavětínská L, Klepetářová B, Hocek M, , C-H Phosphonation of Pyrrolopyrimidines: Synthesis of Substituted 7- and 9-Deazapurine-8-phosphonate Derivatives., J. Org. Chem. 2016, 81, 9507 – 9514.
  • 2016
    Janine Scholefield, Ricardo Henriques, Anca Savulescu, Elisabeth Fontan, Alix F Boucharlat, Emmanuel Laplantine, Asma Smahi, Alain Israël, Fabrice Agou, Musa M Mhlanga, Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti, Nature Communications, 2016, 7, pp.12629. ⟨10.1038/ncomms12629⟩.
  • 2016
    Song L, Risseeuw MDP, Froeyen M, Karalic I, Goeman J, Cappoen D, Van der Eycken J, Cos P, Munier-Lehmann H, Van Calenbergh S, Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents, Bioorg. Med. Chem. 2016 11;24(21):5172-5182.
  • 2016
    Gammage PA, Gaude E, Van Haute L, Rebelo-Guiomar P, Jackson CB, Rorbach J, Pekalski ML, Robinson AJ, Charpentier M, Concordet JP, Frezza C, Minczuk M, Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs, Nucleic Acids Res. 2016 Sep;44(16):7804-16.
  • 2016
    Hu Z, Bongat White AF, Mulard LA, , Efficient Iterative Synthesis of O-Acetylated Tri- to Pentadecasaccharides Related to the Lipopolysaccharide of Shigella flexneri Type 3 a through Di- and Trisaccharide Glycosyl Donors., Chem Asian J 2017 Feb; 12(4): 419-439.
  • 2016
    Adamska A, Rumijowska-Galewicz A, Ruszczynska A, Studzińska M, Jabłońska A, Paradowska E, Bulska E, Munier-Lehmann H, Dziadek J, Leśnikowski ZJ, Olejniczak AB, Anti-mycobacterial activity of thymine derivatives bearing boron clusters, Eur J Med Chem 2016 Oct;121:71-81.
  • 2016
    Böhm UL, Prendergast A, Djenoune L, Nunes Figueiredo S, Gomez J, Stokes C, Kaiser S, Suster M, Kawakami K, Charpentier M, Concordet JP, Rio JP, Del Bene F, Wyart C, CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits, Nat Commun 2016 Mar;7:10866.
  • 2016
    Laubreton D, Bay S, Sedlik C, Artaud C, Ganneau C, Dériaud E, Viel S, Puaux AL, Amigorena S, Gérard C, Lo-Man R, Leclerc C, , The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity., Cancer Immunol Immunother 2016 Mar; 65(3): 315-25.
  • 2016
    Renaud JB, Boix C, Charpentier M, De Cian A, Cochennec J, Duvernois-Berthet E, Perrouault L, Tesson L, Edouard J, Thinard R, Cherifi Y, Menoret S, Fontanière S, de Crozé N, Fraichard A, Sohm F, Anegon I, Concordet JP, Giovannangeli C, Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases, Cell Rep 2016 Mar;14(9):2263-72.
  • 2016
    F. Stauffert, M. L. Lepage, M. M. Pichon, D. Hazelard, A. Bodlenner, P. Compain, A Convenient, Gram-Scale Synthesis of 1-Deoxymannojirimycin, Synthesis, 2016, 48, 1177-1180.
  • 2016
    Grandin C, Hourani ML, Janin YL, Dauzonne D, Munier-Lehmann H, Paturet A, Taborik F, Vabret A, Contamin H, Tangy F, Vidalain PO, Respiratory syncytial virus infection in macaques is not suppressed by intranasal sprays of pyrimidine biosynthesis inhibitors, Antiviral Res. 2016 Jan;125:58-62.
  • 2016
    Niegowska M, Rapini N, Biet F, Piccinini S, Bay S, Lidano R, Manca Bitti ML, Sechi LA, , Seroreactivity against Specific L5P Antigen from Mycobacterium avium subsp. paratuberculosis in Children at Risk for T1D., PLoS One 2016 ; 11(6): e0157962.
  • 2015
    Raj S, Krishnan K, Askew DS, Helynck O, Suzanne P, Lesnard A, Rault S, Zeidler U, d'Enfert C, Latgé JP, Munier-Lehmann H, Saveanu C, The Toxicity of a Novel Antifungal Compound Is Modulated by Endoplasmic Reticulum-Associated Protein Degradation Components, Antimicrob. Agents Chemother. 2015;60(3):1438-49.
  • 2015
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