• 2022
  A. Carrier, C. Desjobert, L. Ponger, L. Lamant, M. Bustos, J. Torres-Ferreira, R. Henrique, C. Jeronimo, L. Lanfrancone, A. Delmas, G. Favre, A. Daunay, F. Busato, D.S.B. Hoon, J. Tost, C. Etievant, J. Riond, P.B. Arimondo, DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness, eLife 2022 Sept. .
• 2022
  Carrier A, Desjobert C, Ponger L, Lamant L, Bustos M, Torres-Ferreira J, Henrique R, Jeronimo C, Lanfrancone L, Delmas A, Favre G, Delaunay A, Busato F, Hoon DSB, Tost J, Etievant C, Riond J, Arimondo PB, , DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness., Elife 2022 Sep; 11(): .
• 2022
  Rahimova R, Nogaret P, Huteau V, Gelin M, Clément DA, Labesse G, Pochet S, Blanc-Potard AB, Lionne C, , Structure-based design, synthesis and biological evaluation of a NAD+ analogue targeting Pseudomonas aeruginosa NAD kinase., FEBS J 2022 Aug; (): .
• 2022
  Flamme, M.; Katkevica, D.; Pajuste, K.; Katkevics, M.; Sabat, N.; Hanlon, S.; Marzuoli, I.; Püntener, K.; Sladojevich, F.; Hollenstein, M., Benzoyl and pivaloyl as efficient protecting groups for controlled enzymatic synthesis of DNA and XNA oligonucleotides, Asian J. Org. Chem. 2022, e202200384.
• 2022
  Planchais C, Fernández I, Bruel T, de Melo GD, Prot M, Beretta M, Guardado-Calvo P, Dufloo J, Molinos-Albert LM, Backovic M, Chiaravalli J, Giraud E, Vesin B, Conquet L, Grzelak L, Planas D, Staropoli I, Guivel-Benhassine F, Hieu T, Boullé M, Cervantes-Gonzalez M, Ungeheuer MN, Charneau P, van der Werf S, Agou F, , , Dimitrov JD, Simon-Lorière E, Bourhy H, Montagutelli X, Rey FA, Schwartz O, Mouquet H, , Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2., J Exp Med 2022 Jul; 219(7): .
• 2022
  A. Carrier, C. Desjobert, L. Ponger, L. Lamant, M. Bustos, J. Torres-Ferreira, R. Henrique, C. Jeronimo, L. Lanfrancone, A. Delmas, G. Favre, A. Daunay, F. Busato, D.S.B. Hoon, J. Tost, C. Etievant, J. Riond, P.B. Arimondo, , DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness, https://biorxiv.org/cgi/content/short/2022.04.11.487909v1.
• 2022
  Sabat, N.; Zhou, W.; Gandon, V.; Guinchard, X.; Vincent, G., Unbiased C3-Electrophilic Indoles: Triflic Acid Mediated C3-Regioselective Hydroarylation of N-H Indoles, Angew. Chem. Int. Ed. 2022, 61, e2022044.
• 2022
  Zhang, Z.; Sabat, N.; Frison, G.; Marinetti, A.; Guinchard, X., Enantioselective Au(I)-Catalyzed Multicomponent Annulation via Tethered Counterion-Directed Catalysis, ACS Catal. 2022, 12, 4046 - 4053.
• 2022
  Sabat, N.; Ouarti, A.; Migianu-Griffoni, E.; Lecouvey, M.; Ferraris, O.; Gallier, F.; Peyrefitte, C.; Lubin-Germain, N.; Uziel, J., Synthesis, antiviral and antitumor activities investigations of a series of Ribavirin C-nucleoside analogue prodrugs, Bioorg. Chem. 2022, 122, 105723.
• 2022
  Chen KY, Krischuns T, Varga LO, Harigua-Souiai E, Paisant S, Zettor A, Chiaravalli J, Delpal A, Courtney D, O'Brien A, Baker SC, Decroly E, Isel C, Agou F, Jacob Y, Blondel A, Naffakh N, , A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors., Antiviral Res 2022 Mar; (): 105272.
• 2022
  Soualmia, F.; Guillot, A.; Sabat, N.; Brewee, C.; Haumann, M.; Guinchard, X.; Benjdia, A.; Berteau, O., Biochemical and XAS investigation of TsrM, a B12-dependent Radical SAM Enzyme Catalyzing Non-radical reaction, Chem. Eur. J. 2022, 28, e2022006.
• 2022
  Si, Y, Bon C, Barbachowska M, Cadet-Daniel V., Jallet C., Soresinetti,L., Boullé M., Duchateau M., Matondo M., Agou, F. Halby L., Arimondo PB, A novel screening strategy to identify histone methyltransferase inhibitors reveals a crosstalk between DOT1L and CARM1, RSC Chemical Biology, 2022, 3, 456 – 467.
• 2022
  Yang Si a, Corentin Bon ORCID logoab, Magdalena Barbachowska ab, Veronique Cadet-Daniel a, Corinne Jallet a, Laura Soresinetti a, Mikaël Boullé c, Magalie Duchateau d, Mariette Matondo d, Fabrice Agou c, Ludovic Halby a and Paola B. Arimondo ORCID logo*a , A novel screening strategy to identify histone methyltransferase inhibitors reveals a crosstalk between DOT1L and CARM1†, DOI: 10.1039/D1CB00095K (Paper) RSC Chem. Biol., 2022, 3, 456-467.
• 2022
  Walter P, Mechaly A, Bous J, Haouz A, England P, Lai-Kee-Him J, Ancelin A, Hoos S, Baron B, Trapani S, Bron P, Labesse G, Munier-Lehmann H, , Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target., FEBS J 2022 Feb; (): .
• 2021
  Song L, Merceron R, Hulpia F, Lucía A, Gracia B, Jian Y, Risseeuw MDP, Verstraelen T, Cos P, Aínsa JA, Boshoff HI, Munier-Lehmann H, Savvides SN, Van Calenbergh S, , Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors., Eur J Med Chem 2021 Dec; 225(): 113784.
• 2021
  Bon C, Arimondo PB, Halby L, , Direct Synthesis of Allyl Amines with 2-Nitrosulfonamide Derivatives via the Tsuji-Trost Reaction., ChemistryOpen 2021 12; 10(12): 1166-1169.
• 2021
  Elie Hammam, Ameya Sinha, Sebastian Baumgarten, Flore Nardella, Jiaqi Liang, Samia Miled, Frédéric Bonhomme, Diane Erdmann, Benoit Arcangioli, Paola B. Arimondo, Peter Dedon, Peter Preiser, Artur Scherf, Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation, mBio. 2021 Nov-Dec; 12(6): e02558-21.
• 2021
  Luviano N, Lopez M, Gawehns F, Chaparro C, Arimondo PB, Ivanovic S, David P, Verhoeven K, Cosseau C, Grunau C, , The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor., Epigenetics Chromatin 2021 10; 14(1): 48.
• 2021
  Anca F. Savulescu, Robyn Brackin, Emmanuel Bouilhol, Benjamin Dartigues, Jonathan H. Warrell, Mafalda R. Pimentel, Nicolas Beaume, Isabela C. Fortunato, Stephane Dallongeville, Mikaël Boullé, Hayssam Soueidan, Fabrice Agou, Jan Schmoranzer, Jean-Christophe Olivo-Marin, Claudio A. Franco, Edgar R. Gomes, Macha Nikolski, and Musa M. Mhlanga , Interrogating RNA and protein spatial subcellular distribution in smFISH data with DypFISH, Volume 1, Issue 5, 27 September 2021, 100068.
• 2021
  Meyer B, Chiaravalli J, Gellenoncourt S, Brownridge P, Bryne DP, Daly LA, Grauslys A, Walter M, Agou F, Chakrabarti LA, Craik CS, Eyers CE, Eyers PA, Gambin Y, Jones AR, Sierecki E, Verdin E, Vignuzzi M, Emmott E, , Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential., Nat Commun 2021 09; 12(1): 5553.
• 2021
  Mathieu C, Touret F, Jacquemin C, Janin YL, Nougairède A, Brailly M, Mazelier M, Décimo D, Vasseur V, Hans A, Valle-Casuso JC, de Lamballerie X, Horvat B, André P, Si-Tahar M, Lotteau V, Vidalain PO, , A Bioluminescent 3CLPro Activity Assay to Monitor SARS-CoV-2 Replication and Identify Inhibitors., Viruses 2021 Sep; 13(9): .
• 2021
  Hosseiniporgham S, Biet F, Ganneau C, Bannantine JP, Bay S, Sechi LA, , A Comparative Study on the Efficiency of Two Mycobacterium avium subsp. paratuberculosis (MAP)-Derived Lipopeptides of L3P and L5P as Capture Antigens in an In-House Milk ELISA Test., Vaccines (Basel) 2021 Sep; 9(9): .
• 2021
  Zahradník J, Marciano S, Shemesh M, Zoler E, Harari D, Chiaravalli J, Meyer B, Rudich Y, Li C, Marton I, Dym O, Elad N, Lewis MG, Andersen H, Gagne M, Seder RA, Douek DC, Schreiber G, , SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution., Nat Microbiol 2021 09; 6(9): 1188-1198.
• 2021
  , Towards the sustainable discovery and development of new antibiotics, Nat Rev Chem. 2021 Aug 19:1-24.
• 2021
  Bon C, Si, Y, Pernak M, Barbachowska, M, Levi-Acobas, E, Cadet Daniel, V, Jallet C, Ruzic D, Djokovic N, Djikić T., Nikolic K, Halby L, Arimondo PB, Synthesis and Biological Activity of a Cytostatic Inhibitor of MLLr Leukemia Targeting the DOT1L Protein, Molecules 2021, 26(17), 5300 .
• 2021
  Czernecki D, Bonhomme F, Kaminski PA, Delarue M, , Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA., Nat Commun 2021 08; 12(1): 4710.
• 2021
  Lavigne M, Helynck O, Rigolet P, Boudria-Souilah R, Nowakowski M, Baron B, Brülé S, Hoos S, Raynal B, Guittat L, Beauvineau C, Petres S, Granzhan A, Guillon J, Pratviel G, Teulade-Fichou MP, England P, Mergny JL, Munier-Lehmann H, , SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction., Nucleic Acids Res 2021 Jul; (): .
• 2021
  Cohen D, Atsmon J, Artaud C, Meron-Sudai S, Gougeon ML, Bialik A, Goren S, Asato V, Ariel-Cohen O, Reizis A, Dorman A, Hoitink CWG, Westdijk J, Ashkenazi S, Sansonetti P, Mulard LA, Phalipon A, , Safety and immunogenicity of a synthetic carbohydrate conjugate vaccine against Shigella flexneri 2a in healthy adult volunteers: a phase 1, dose-escalating, single-blind, randomised, placebo-controlled study., Lancet Infect Dis 2021 04; 21(4): 546-558.
• 2021
  Dhara D, Mulard LA, , Exploratory N-Protecting Group Manipulation for the Total Synthesis of Zwitterionic Shigella sonnei Oligosaccharides., Chemistry 2021 Mar; 27(18): 5694-5711.
• 2021
  Hu Z, Benkoulouche M, Barel LA, Le Heiget G, Ben Imeddourene A, Le Guen Y, Monties N, Guerreiro C, Remaud-Siméon M, Moulis C, André I, Mulard LA, , Convergent Chemoenzymatic Strategy to Deliver a Diversity of Shigella flexneri Serotype-Specific O-Antigen Segments from a Unique Lightly Protected Tetrasaccharide Core., J Org Chem 2021 02; 86(3): 2058-2075.
• 2021
  Benkoulouche M, Ben Imeddourene A, Barel LA, Le Heiget G, Pizzut S, Kulyk H, Bellvert F, Bozonnet S, Mulard LA, Remaud-Siméon M, Moulis C, André I, , Redirecting substrate regioselectivity using engineered ΔN123-GBD-CD2 branching sucrases for the production of pentasaccharide repeating units of S. flexneri 3a, 4a and 4b haptens., Sci Rep 2021 01; 11(1): 2474.
• 2021
  Gagnot G, Hervin V, Coutant EP, Goyard S, Jacob Y, Rose T, Hibti FE, Quatela A, Janin YL, , Core-Modified Coelenterazine Luciferin Analogues: Synthesis and Chemiluminescence Properties., Chemistry 2021 Jan; 27(6): 2112-2123.
• 2021
  Jian Y, Forbes HE, Hulpia F, Risseeuw MDP, Caljon G, Munier-Lehmann H, Boshoff HIM, Van Calenbergh S, , 2-((3,5-Dinitrobenzyl)thio)quinazolinones: Potent Antimycobacterial Agents Activated by Deazaflavin (F420)-Dependent Nitroreductase (Ddn)., J Med Chem 2021 01; 64(1): 440-457.
• 2021
  Fernandez J, Hassen-Khodja C, Georget V, Rose T, Jacob Y, Janin YL, Nisole S, Vidalain PO, Arhel NJ, , Measuring the subcellular compartmentalization of viral infections by protein complementation assay., Proc Natl Acad Sci U S A 2021 01; 118(2): .
• 2021
  Bay S, Begg D, Ganneau C, Branger M, Cochard T, Bannantine JP, Köhler H, Moyen JL, Whittington RJ, Biet F, , Engineering Synthetic Lipopeptide Antigen for Specific Detection of Mycobacterium avium subsp. paratuberculosis Infection., Front Vet Sci 2021 ; 8(): 637841.
• 2020
  Jian Y, Merceron R, De Munck S, Forbes HE, Hulpia F, Risseeuw MDP, Van Hecke K, Savvides SN, Munier-Lehmann H, Boshoff HIM, Van Calenbergh S, , Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents., Eur J Med Chem 2020 Nov; 206(): 112659.
• 2020
  Goyard S, Balbino B, Chinthrajah RS, Lyu SC, Janin YL, Bruhns P, Poncet P, Galli SJ, Nadeau KC, Reber LL, Rose T, , A highly sensitive bioluminescent method for measuring allergen-specific IgE in microliter samples., Allergy 2020 11; 75(11): 2952-2956.
• 2020
  Clément DA, Leseigneur C, Gelin M, Coelho D, Huteau V, Lionne C, Labesse G, Dussurget O, Pochet S, , New Chemical Probe Targeting Bacterial NAD Kinase., Molecules 2020 Oct; 25(21): .
• 2020
  Thieulent C, Hue E, Sutton G, Fortier C, Dallemagne P, Zientara S, Munier-Lehmann H, Hans A, Paillot R, Vidalain PO, Pronost S, , Identification of antiviral compounds against equid herpesvirus-1 using real-time cell assay screening: efficacy of decitabine and valganciclovir alone or in combination., Antiviral Res. 2020 Sep; (): 104931.
• 2020
  Jian Y, Hulpia F, Risseeuw MDP, Forbes HE, Munier-Lehmann H, Caljon G, Boshoff HIM, Van Calenbergh S, , Synthesis and structure activity relationships of cyanopyridone based anti-tuberculosis agents., Eur J Med Chem 2020 Sep; 201(): 112450.
• 2020
  Bon C, Halby L, Arimondo PB, , Bisubstrate inhibitors: the promise of a selective and potent chemical inhibition of epigenetic ‘writers’., Epigenomics 2020 09; 12(17): 1479-1482.
• 2020
  Milcendeau, P.; Sabat, N.; Ferry, A.; Guinchard, X., Gold-Catalyzed Enantioselective Functionalizations of Indoles, Org. Biomol. Chem. 2020, 18, 6006 – 6017.
• 2020
  Topart C, Werner E, Arimondo PB, , Wandering along the epigenetic timeline., Clin Epigenetics 2020 07; 12(1): 97.
• 2020
  Valle-Casuso JC, Gaudaire D, Martin-Faivre L, Madeline A, Dallemagne P, Pronost S, Munier-Lehmann H, Zientara S, Vidalain PO, Hans A, , Replication of Equine arteritis virus is efficiently suppressed by purine and pyrimidine biosynthesis inhibitors., Sci Rep 2020 Jun; 10(1): 10100.
• 2020
  Jian Y, Hulpia F, D P Risseeuw M, Forbes HE, Caljon G, Munier-Lehmann H, I M Boshoff H, Van Calenbergh S, , 1-(1-Arylethylpiperidin-4-yl)thymine Analogs as Antimycobacterial TMPK Inhibitors., Molecules 2020 Jun; 25(12): .
• 2020
  Encarnação JC, Napolitano V, Opassi G, Danielson UH, Dubin G, Popowicz GM, Munier-Lehmann H, Buijs J, Andersson K, Björkelund H, , A real-time cell-binding assay reveals dynamic features of STxB-Gb3 cointernalization and STxB-mediated cargo delivery into cancer cells., FEBS Lett. 2020 May; (): .
• 2020
  Sabat, N.; Soualmia, F.; Retailleau, P.; Bendjdia, A.; Berteau, O.; Guinchard, X., Gold-Catalyzed Spirocyclization Reactions of N-propargyl Tryptamines and Tryptophanes in Aqueous Media, Org. Lett. 2020, 22, 4344 – 4349.
• 2020
  Olivier Borkowski, Mathilde Koch, Agnès Zettor, Amir Pandi, Angelo Cardoso Batista, Paul Soudier, Jean-Loup Faulon, Large Scale Active-Learning-Guided Exploration for in Vitro Protein Production Optimization, Nat Commun. 2020 Apr 20;11(1):1872.
• 2020
  Pechalrieu D, Assemat F, Halby L, Marcellin M, Yan P, Chaoui K, Sharma S, Chiosis G, Burlet-Schiltz O, Arimondo PB, Lopez M, , Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs., ACS Chem Biol 2020 04; 15(4): 952-961.
• 2020
  Gelin M, Paoletti J, Nahori MA, Huteau V, Leseigneur C, Jouvion G, Dugué L, Clément D, Pons JL, Assairi L, Pochet S, Labesse G, Dussurget O, , From Substrate to Fragments to Inhibitor Active In Vivo against Staphylococcus aureus., ACS Infect Dis 2020 03; 6(3): 422-435.
• 2020
  Nardella F, Halby L, Hammam E, Erdmann D, Cadet-Daniel V, Peronet R, Ménard D, Witkowski B, Mecheri S, Scherf A, Arimondo PB, , DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites., ACS Cent Sci 2020 Jan; 6(1): 16-21.
• 2020
  Vichier-Guerre S, Ku T, Pochet S, Seley-Radtke KL, An expedient synthesis of flexible nucleosides through enzymatic glycosylation of proximal and distal fleximer bases, Chembiochem 2020 Jan;.
• 2019
  Sabat, N.; Migianu-Griffoni, E.; Tudela, T.; Lecouvey, M.; Kellouche, S.; Carreiras, F.; Gallier, F.; Uziel, J.; Lubin-Germain, N., Synthesis and antitumor activities investigation of a C-nucleoside analogue of ribavirin, Eur. J. Med. Chem. 2020, 188, 112009.
• 2019
  Jian Y, Risseeuw MDP, Froeyen M, Song L, Cappoen D, Cos P, Munier-Lehmann H, van Calenbergh S, , 1-(Piperidin-3-yl)thymine amides as inhibitors of M. tuberculosis thymidylate kinase., J Enzyme Inhib Med Chem 2019 Dec; 34(1): 1730-1739.
• 2019
  Bon C, Erdmann D, Halby L, Arimondo PB, , [Chemical targeting of DNA and histone methylation in cancer: Novelties, hopes and promises]., Bull Cancer 2019 Oct; 106(10): 823-833.
• 2019
  Said Halidi KN, Fontan E, Boucharlat A, Davignon L, Charpentier M, Boullé M, Weil R, Israël A, Laplantine E, Agou F., Two NEMO-like Ubiquitin-Binding Domains in CEP55 Differently Regulate Cytokinesis., iScience. 2019 Sep 25;20:292-309.
• 2019
  M. M. Pichon, D. Hazelard, P. Compain, Metal-Free Deoxygenation of α-Hydroxy Carbonyl Compounds and Beyond, Eur JOC, 2019, 37, 6320-6332.
• 2019
  Reolon LW, Vichier-Guerre S, de Matos BM, Dugué L, Assunção TRDS, Zanchin NIT, Pochet S, Guimarães BG, Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4, Nucleic Acids Res. 2019 Jun;47(11):5973-5987.
• 2019
  Arimondo PB, Barberousse A, Pontarotti G, , The Many Faces of EpigeneticsOxford, December 2017., Epigenetics 2019 06; 14(6): 623-631.
• 2019
  M. M. Pichon, F. Stauffert, A. Bodlenner, P. Compain, Tight-binding inhibition of jack bean α-mannosidase by glycoimidazole clusters, Org. Biomol. Chem., 2019, 17, 5801-5817.
• 2019
  Alexandre T, Lupan A, Helynck O, Vichier-Guerre S, Dugué L, Gelin M, Haouz A, Labesse G, Munier-Lehmann H, First-in-class allosteric inhibitors of bacterial IMPDHs, Eur J Med Chem 2019 Feb;167:124-132.
• 2019
  Vichier-Guerre S, Dugué L, Pochet S, 2′-Deoxyribonucleoside 5′-triphosphates bearing 4-phenyl and 4-pyrimidinyl imidazoles as DNA polymerase substrates, Org. Biomol. Chem. 2019 01;17(2):290-301.
• 2019
  Thieulent CJ, Hue ES, Fortier CI, Dallemagne P, Zientara S, Munier-Lehmann H, Hans A, Fortier GD, Pitel PH, Vidalain PO, Pronost SL, Screening and evaluation of antiviral compounds against Equid alpha-herpesviruses using an impedance-based cellular assay, Virology 2019 01;526:105-116.
• 2019
  Barel LA, Mulard LA, , Classical and novel strategies to develop a Shigella glycoconjugate vaccine: from concept to efficacy in human., Hum Vaccin Immunother 2019 ; 15(6): 1338-1356.
• 2018
  García-Weber D, Dangeard AS, Cornil J, Thai L, Rytter H, Zamyatina A, Mulard LA, Arrieumerlou C, , ADP-heptose is a newly identified pathogen-associated molecular pattern of Shigella flexneri., EMBO Rep 2018 12; 19(12): .
• 2018
  Kunstmann S, Scheidt T, Buchwald S, Helm A, Mulard LA, Fruth A, Barbirz S, , Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens., Viruses 2018 08; 10(8): .
• 2018
  Laskaris P, Vicentefranqueira R, Helynck O, Jouvion G, Calera JA, du Merle L, Suzenet F, Buron F, de Sousa RA, Mansuy D, Cavaillon JM, Latgé JP, Munier-Lehmann H, Ibrahim-Granet O, A Novel Polyaminocarboxylate Compound To Treat Murine Pulmonary Aspergillosis by Interfering with Zinc Metabolism, Antimicrob. Agents Chemother. 2018 Jun;62(6).
• 2018
  Sabat, N.; Poštová Slavětínská, L.; Klepetářová, B.; Hocek, M., C-H Imidation of 7-Deazapurines., ACS Omega. 2018, 3, 4674 – 4678.
• 2018
  Charpentier M, Khedher AHY, Menoret S, Brion A, Lamribet K, Dardillac E, Boix C, Perrouault L, Tesson L, Geny S, De Cian A, Itier JM, Anegon I, Lopez B, Giovannangeli C and Concordet JP, CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair., Nat Commun. 2018 Mar 19;9(1):1133.
• 2018
  Song L, Merceron R, Gracia B, Quintana AL, Risseeuw MDP, Hulpia F, Cos P, Aínsa JA, Munier-Lehmann H, Savvides SN, Van Calenbergh S, Structure Guided Lead Generation toward Nonchiral M. tuberculosis Thymidylate Kinase Inhibitors, J. Med. Chem. 2018 Apr;61(7):2753-2775.
• 2018
  Vincenzo Di Donato, Flavia De Santis, Shahad Albadri, Thomas Oliver Auer, Karine Duroure, Marine Charpentier, Jean-Paul Concordet, Christoph Gebhardt, and Filippo Del Bene, An Attractive Reelin Gradient Establishes Synaptic Lamination in the Vertebrate Visual System, Neuron. 2018 Feb 5. pii: S0896-6273(18)30055-2..
• 2018
  Valentine Mosbach, Lucie Poggi, David Viterbo, Marine Charpentier and Guy-Franck Richard, TALEN-Induced Double-Strand Break Repair of CTG Trinucleotide Repeats., Cell Rep. 2018 Feb 20;22(8):2146-2159.
• 2018
  M. M. Pichon, F. Stauffert, L. G. Addante-Moya, A. Bodlenner, P. Compain, Metal-Free Iodine-Mediated Deoxygenation of Alcohols in the Position α to Electron-Withdrawing Groups, Eur. JOC, 2018, 13, 1538-1545.
• 2018
  Harigua-Souiai E, Abdelkrim YZ, Bassoumi-Jamoussi I, Zakraoui O, Bouvier G, Essafi-Benkhadir K, Banroques J, Desdouits N, Munier-Lehmann H, Barhoumi M, Tanner NK, Nilges M, Blondel A, Guizani I, Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A, PLoS Negl Trop Dis 2018 01;12(1):e0006160.
• 2018
  Suthagar K, Jiao W, Munier-Lehmann H, Fairbanks AJ, Synthesis of sulfamide analogues of deoxthymidine monophosphate as potential inhibitors of mycobacterial cell wall biosynthesis, Carbohydr. Res. 2018 Mar;457:32-40.
• 2017
  Dabo S., Maillard P., Collados Rodriguez M., Hansen M. D., Mazouz S., Bigot D. J., Tible M., Janvier G., Helynck O., Cassonnet P., Jacob Y., Bellalou J., Gatignol A., Patel R. C., Hugon J., Munier-Lehmann H., Meurs E. F., Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT, Sci Rep. 2017 Nov 23;7(1):16129.
• 2017
  Sabat, N.; Smolén. S.; Nauš, P.; Perlíková. P.; Cebová. M.; Poštová Slavětínská, L.; Hocek, M., Synthesis of 2,6-Substituted-7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted-5-(Het)aryl-pyrrolo[2,3-d]pyrimidines, Synthesis. 2017, 49, 4623 – 4650.
• 2017
  D. Hazelard, M. L. Lepage, J. P. Schneider, M. M. Pichon, F. Massicot, P. Compain, Large Scale Synthesis of 2,3,4,6-Tetra-O-Benzyl-1-Deoxynojirimycin, Carbohydrates Chemistry: ProvenSyntheticMethods, Vol.4, 2017, 303-314.
• 2017
  Buchieri MV, Cimino M, Rebollo-Ramirez S, Beauvineau C, Cascioferro A, Favre-Rochex S, Helynck O, Naud-Martin D, Larrouy-Maumus G, Munier-Lehmann H, Gicquel B, Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in Mycobacterium smegmatis, J. Med. Chem. 2017 Sep 14;60(17):7425-7433.
• 2017
  Lucas-Hourani M, Dauzonne D, Munier-Lehmann H, Khiar S, Nisole S, Dairou J, Helynck O, Afonso PV, Tangy F, Vidalain PO, Original chemical series of pyrimidine biosynthesis inhibitors that boost the antiviral interferon response, Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00383-17.
• 2017
  Khiar S, Lucas-Hourani M, Nisole S, Smith N, Helynck O, Bourgine M, Ruffié C, Herbeuval JP, Munier-Lehmann H, Tangy F, Vidalain PO, Identification of a small molecule that primes the type I interferon response to cytosolic DNA, Sci Rep 2017 05;7(1):2561.
• 2017
  Eckenfelder A, Ségéral E, Pinzón N, Ulveling D, Amadori C, Charpentier M, Nidelet S, Concordet JP, Zagury JF, Paillart JC, Berlioz-Torrent C, Seitz H, Emiliani S, Gallois-Montbrun S, Argonaute proteins regulate HIV-1 multiply spliced RNA and viral production in a Dicer independent manner, Nucleic Acids Res. 2017 Apr;45(7):4158-4173.
• 2017
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• 2017
  Koseki Y, Kanetaka H, Tsunosaki J, Munier-Lehmann H, Aoki S, Tetrahydro-2-furanyl-2,4(1H,3H)-pyrimidinedione derivatives as novel antibacterial compounds against Mycobacterium, Int. J. Mycobacteriol. 2017 Jan-Mar;6(1):61-69.
• 2017
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• 2017
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• 2017
  Phillips AF, Millet AR, Tigano M, Dubois SM, Crimmins H, Babin L, Charpentier M, Piganeau M, Brunet E, Sfeir A, Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion, Mol. Cell 2017 Feb;65(3):527-538.e6.
• 2016
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• 2016
  Sabat, N.; Nauš, P.; Matyašovský, J.; Dziuba, D.; Poštová Slavetínská, L.; Hocek, M., Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions, Synthesis. 2016, 48, 1029 – 1045.
• 2016
  Paoletti J, Assairi L, Gelin M, Huteau V, Nahori MA, Dussurget O, Labesse G, Pochet S, , 8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode., Eur J Med Chem 2016 Nov; 124(): 1041-1056.
• 2016
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• 2016
  Scholefield J, Henriques R, Savulescu AF, Fontan E, Boucharlat A, Laplantine E, Smahi A, Israël A, Agou F* and Mhlanga MM*., Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti, Nat Commun. 2016 Sep 2;7:12629.
• 2016
  Song L, Risseeuw MDP, Froeyen M, Karalic I, Goeman J, Cappoen D, Van der Eycken J, Cos P, Munier-Lehmann H, Van Calenbergh S, Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents, Bioorg. Med. Chem. 2016 11;24(21):5172-5182.
• 2016
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• 2016
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• 2016
  Adamska A, Rumijowska-Galewicz A, Ruszczynska A, Studzińska M, Jabłońska A, Paradowska E, Bulska E, Munier-Lehmann H, Dziadek J, Leśnikowski ZJ, Olejniczak AB, Anti-mycobacterial activity of thymine derivatives bearing boron clusters, Eur J Med Chem 2016 Oct;121:71-81.
• 2016
  Böhm UL, Prendergast A, Djenoune L, Nunes Figueiredo S, Gomez J, Stokes C, Kaiser S, Suster M, Kawakami K, Charpentier M, Concordet JP, Rio JP, Del Bene F, Wyart C, CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits, Nat Commun 2016 Mar;7:10866.
• 2016
  Renaud JB, Boix C, Charpentier M, De Cian A, Cochennec J, Duvernois-Berthet E, Perrouault L, Tesson L, Edouard J, Thinard R, Cherifi Y, Menoret S, Fontanière S, de Crozé N, Fraichard A, Sohm F, Anegon I, Concordet JP, Giovannangeli C, Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases, Cell Rep 2016 Mar;14(9):2263-72.
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• 2016
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• 2015
  Raj S, Krishnan K, Askew DS, Helynck O, Suzanne P, Lesnard A, Rault S, Zeidler U, d'Enfert C, Latgé JP, Munier-Lehmann H, Saveanu C, The Toxicity of a Novel Antifungal Compound Is Modulated by Endoplasmic Reticulum-Associated Protein Degradation Components, Antimicrob. Agents Chemother. 2015;60(3):1438-49.
• 2015
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• 2015
  Labesse G, Alexandre T, Gelin M, Haouz A, Munier-Lehmann H, Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation, Acta Crystallogr. D Biol. Crystallogr. 2015 Sep;71(Pt 9):1890-9.
• 2015
  Lucas-Hourani M, Munier-Lehmann H, El Mazouni F, Malmquist NA, Harpon J, Coutant EP, Guillou S, Helynck O, Noel A, Scherf A, Phillips MA, Tangy F, Vidalain PO, Janin YL, Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH), J. Med. Chem. 2015 Jul;58(14):5579-98.
• 2015
  Alexandre T, Raynal B, Rayna B, Munier-Lehmann H, Two classes of bacterial IMPDHs according to their quaternary structures and catalytic properties, PLoS ONE 2015;10(2):e0116578.
• 2015
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• 2015
  Dubosclard V, Fontan E, Agou F, Use of fluorescence spectroscopy for quantitative investigations of ubiquitin interactions with the ubiquitin-binding domains of NEMO, Methods Mol. Biol. 2015;1280:321-37.
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• 2014
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