I did my bachelor studies in the Ecole Normale Supérieure in Paris. After a long hesitation between evolution, ecology and developmental and cell biology, a long internship working on C. elegans early development (in Pr. Seydoux lab, John Hopkins University) definitly pushed me toward cell and developmental biology side. My interest for quantitative approaches brought me to an interdisciplinary master (AIV, Paris) where I start being interested by morphogenesis. I then joinded the laboratory of Thomas Lecuit (IBDM, Marseille, France) to start my PhD working on epithelial morphogenesis in early Drosophila embryo and the role of the modulation of cell-cell adhesion. I then moved to Switzerland in the group of Eduardo Moreno for my postdoc (IZB, University of Bern) working on cell competition. I eventually moved back to Paris in December 2016 to start my research group in the Institut Pasteur. .
Le programme de biologie quantitative de l’Institut Pasteur est destiné à faciliter la recherche et l’éducation à l’interface entre la biologie et les sciences plus quantitatives. L’un des principaux objectifs de la biologie quantitative […]
ERC CoG PrApEDoC: Predicting Apoptosis Engagement Downstream of Caspases in vivo
Epithelial cell death is widespread during development and tissue homeostasis. While the core pathway of apoptosis is well known, we lack predictive power to understand when and where a specific cell will die in […]
Commitment to apoptosis and the orchestration of cell clearance
Despite the detailed characterisation of the molecular players of apoptosis, its orchestration and fine regulation in multicellular contexts is not well understood. While apoptosis is often considered as a simple binary process, there are nowadays many evidences showing […]
ERC-2017-StG_CoSpaDD: Competition for space in development and disease
Despite our deep knowledge of the pathways regulating cell proliferation, growth and survival, we still do not understand how single cells can match their behavior to properties of the entire tissue (including its size and shape). Mechanical […]
2023Emerging roles and mechanisms of ERK pathway mechanosensing., Cell Mol Life Sci 2023 Nov; 80(12): 355.
2023Toward a predictive understanding of epithelial cell death., Semin Cell Dev Biol 2023 Jul; (): .
2023DeXtrusion: automatic recognition of epithelial cell extrusion through machine learning in vivo., Development 2023 Jul; 150(13): .
2023In vitro cellular reprogramming to model gonad development and its disorders., Sci Adv 2023 Jan; 9(1): eabn9793.
2023Cell polarity and extrusion: How to polarize extrusion and extrude misspolarized cells?, Curr Top Dev Biol 2023 ; 154(): 131-167.
2022Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network., Biomolecules 2022 Jun; 12(7): .
2022Microtubule disassembly by caspases is an important rate-limiting step of cell extrusion., Nat Commun 2022 Jun; 13(1): 3632.
2021Collective effects in epithelial cell death and cell extrusion., Curr Opin Genet Dev 2022 02; 72(): 8-14.
2021Cell competition: Bridging the scales through cell-based modeling., Curr Biol 2021 Jul; 31(13): R856-R858.
2021LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images., BMC Biol 2021 07; 19(1): 136.
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