Timeline

Romain Levayer

Head of Structure

14 Jan 2026

event

Qbio minisymposium: Probing tissue mechanics

07 Jan 2026

event

DSCB & Immunology Dept. Joint Seminar, Prof. Emmanuelle Passegué, from Columbia University Irving Medical Center, NY, USA. ” Hematopoietic Stem Cells in Stress, Disease & Aging”.

12 Dec 2025

event

DSCB – Out of the Box – Christmas Seminar: Prof. Evelyne Heyer from Muséum National d’Histoire Naturelle, Paris, France

04 Dec 2025

event

DSCB Seminar: Dr. Virginie Courtier, Institut Jacques Monod, Paris, France – “Drosophila glue: biomechanics, genome evolution and (micro)ecology”

10 Oct 2025

news

Cancer cells tighten the belt around their neighbours forcing them to die

09 Oct 2025

publication

Interfacial tension and growth both contribute to mechanical cell competition.

18 Sep 2025

publication

Signaling-dependent refinement of cell fate choice during tissue remodeling in Drosophila pupal wings.

12 Sep 2025

event

Qbio minisymposium: Metronomes of life

28 Jul 2025

publication

Special issue: “Novel functions of programmed cell death in development: Current status and future challenges”.

23 Jun 2025

event

TripToTech, the 2025 Triptych Event

15 Apr 2025

publication

Epithelial cell extrusion at a glance.

21 Nov 2024

news

On Mon 11/18, we held a mini symposium on the novel perspectives in human embryo research and Stem cell day. Lively discussions thanks to our prominent speakers and participants!

21 Nov 2024

news

On Monday, November 18, we held a Minisymposium on the new perspectives of human embryo research and STEM CELL DAY. Lively discussions thanks to our outstanding speakers and participants!

21 Nov 2024

news

On Mon 11/18, we held a Mini-Symposium: “The Human Embryo: Novel Perspectives in Research and Disease Mechanisms” and STEM CELL DAY. Lively discussions thanks to our prominent speakers and participants!

18 Jan 2024

news

How spatial bias in apoptosis can modulate tissue shape and size?

09 Jan 2024

publication

Staying away from the breaking point: Probing the limits of epithelial cell elimination.

09 Jan 2024

publication

Patterned apoptosis has an instructive role for local growth and tissue shape regulation in a fast-growing epithelium.

10 Nov 2023

publication

Emerging roles and mechanisms of ERK pathway mechanosensing.

20 Sep 2023

project

ERC Consolidator Grant PrApEDoC: Predicting Apoptosis Engagement Downstream of Caspasese

01 Jul 2023

publication

Toward a predictive understanding of epithelial cell death.

30 Jun 2023

news

Romain Levayer laureate of the Pasteur Vallery-Radot prize 2023

07 Jun 2023

publication

DeXtrusion: automatic recognition of epithelial cell extrusion through machine learning in vivo.

31 Jan 2023

news

ERC Consolidator grant 2022: congratulations to Romain Levayer

04 Jan 2023

publication

In vitro cellular reprogramming to model gonad development and its disorders.

01 Jan 2023

publication

Cell polarity and extrusion: How to polarize extrusion and extrude misspolarized cells?

19 Jul 2022

news

New publication – Microtubules depletion by effector caspases is an important rate-limiting step of extrusion

28 Jun 2022

publication

Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network.

25 Jun 2022

publication

Microtubule disassembly by caspases is an important rate-limiting step of cell extrusion.

01 Feb 2022

publication

Collective effects in epithelial cell death and cell extrusion

12 Jul 2021

publication

Cell competition: Bridging the scales through cell-based modeling.

02 Jul 2021

publication

LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images.

21 Jun 2021

publication

Robustness of epithelial sealing is an emerging property of local ERK feedback driven by cell elimination.

02 Jun 2021

news

Dying cells protect their neighbours to maintain the cohesion of our tissues

22 Jan 2021

publication

Cell scientist to watch- Romain Levayer

24 Feb 2020

publication

Cell Extrusion: Crowd Pushing and Sticky Neighbours.

05 Aug 2019

publication

Multiple Influences of Mechanical Forces on Cell Competition

08 May 2019

publication

Solid stress, competition for space and cancer: The opposing roles of mechanical cell competition in tumour initiation and growth.

12 Feb 2019

team

UMR3738 – Developmental and Stem Cell Biology

07 Jan 2019

publication

Competition for Space Induces Cell Elimination through Compaction-Driven ERK Downregulation.

04 Jan 2019

publication

Dying under pressure: cellular characterisation and in vivo functions of cell death induced by compaction

09 Jul 2018

publication

Cell Competition: How to Take Over the Space Left by Your Neighbours

31 Jan 2017

team

Cell death and epithelial homeostasis

12 Dec 2016

project

Commitment to apoptosis and the orchestration of cell clearance

27 Oct 2016

project

ERC-2017-StG_CoSpaDD: Competition for space in development and disease

16 Jun 2016

publication

Survival of the Fittest: Essential Roles of Cell Competition in Development, Aging, and Cancer

10 Jun 2016

program_project

Quantitative biology

07 Mar 2016

publication

Tissue Crowding Induces Caspase-Dependent Competition for Space.

05 Jan 2016

publication

How to be in a good shape? The influence of clone morphology on cell competition

19 Aug 2015

publication

Cell mixing induced by myc is required for competitive tissue invasion and destruction

15 Sep 2014

department

Developmental and Stem Cell Biology

18 Jul 2013

publication

Oscillation and polarity of E-cadherin asymmetries control actomyosin flow patterns during morphogenesis

18 Mar 2013

publication

Mechanisms of cell competition: themes and variations

22 Nov 2012

publication

[Regulation of intercellular adhesion during epithelial morphogenesis]

25 Nov 2011

publication

Biomechanical regulation of contractility: spatial control and dynamics

24 Apr 2011

publication

Spatial regulation of Dia and Myosin-II by RhoGEF2 controls initiation of E-cadherin endocytosis during epithelial morphogenesis

01 Jul 2008

publication

A little guide for advanced search:

Qbio minisymposium: Probing tissue mechanics

DSCB & Immunology Dept. Joint Seminar, Prof. Emmanuelle Passegué, from Columbia University Irving Medical Center, NY, USA. ” Hematopoietic Stem Cells in Stress, Disease & Aging”.

DSCB – Out of the Box – Christmas Seminar: Prof. Evelyne Heyer from Muséum National d’Histoire Naturelle, Paris, France

DSCB Seminar: Dr. Virginie Courtier, Institut Jacques Monod, Paris, France – “Drosophila glue: biomechanics, genome evolution and (micro)ecology”

Cancer cells tighten the belt around their neighbours forcing them to die

Interfacial tension and growth both contribute to mechanical cell competition.

Signaling-dependent refinement of cell fate choice during tissue remodeling in Drosophila pupal wings.

Qbio minisymposium: Metronomes of life

Special issue: “Novel functions of programmed cell death in development: Current status and future challenges”.

TripToTech, the 2025 Triptych Event

Epithelial cell extrusion at a glance.

On Mon 11/18, we held a mini symposium on the novel perspectives in human embryo research and Stem cell day. Lively discussions thanks to our prominent speakers and participants!

On Monday, November 18, we held a Minisymposium on the new perspectives of human embryo research and STEM CELL DAY. Lively discussions thanks to our outstanding speakers and participants!

On Mon 11/18, we held a Mini-Symposium: “The Human Embryo: Novel Perspectives in Research and Disease Mechanisms” and STEM CELL DAY. Lively discussions thanks to our prominent speakers and participants!

How spatial bias in apoptosis can modulate tissue shape and size?

Staying away from the breaking point: Probing the limits of epithelial cell elimination.

Patterned apoptosis has an instructive role for local growth and tissue shape regulation in a fast-growing epithelium.

Emerging roles and mechanisms of ERK pathway mechanosensing.

ERC Consolidator Grant PrApEDoC: Predicting Apoptosis Engagement Downstream of Caspasese

Toward a predictive understanding of epithelial cell death.

Romain Levayer laureate of the Pasteur Vallery-Radot prize 2023

DeXtrusion: automatic recognition of epithelial cell extrusion through machine learning in vivo.

ERC Consolidator grant 2022: congratulations to Romain Levayer

In vitro cellular reprogramming to model gonad development and its disorders.

Cell polarity and extrusion: How to polarize extrusion and extrude misspolarized cells?

New publication – Microtubules depletion by effector caspases is an important rate-limiting step of extrusion

Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network.

Microtubule disassembly by caspases is an important rate-limiting step of cell extrusion.

Collective effects in epithelial cell death and cell extrusion

Cell competition: Bridging the scales through cell-based modeling.

LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images.

Robustness of epithelial sealing is an emerging property of local ERK feedback driven by cell elimination.

Dying cells protect their neighbours to maintain the cohesion of our tissues

Cell scientist to watch- Romain Levayer

Cell Extrusion: Crowd Pushing and Sticky Neighbours.

Multiple Influences of Mechanical Forces on Cell Competition

Solid stress, competition for space and cancer: The opposing roles of mechanical cell competition in tumour initiation and growth.

UMR3738 – Developmental and Stem Cell Biology

Competition for Space Induces Cell Elimination through Compaction-Driven ERK Downregulation.

Dying under pressure: cellular characterisation and in vivo functions of cell death induced by compaction

Cell Competition: How to Take Over the Space Left by Your Neighbours

Cell death and epithelial homeostasis

Commitment to apoptosis and the orchestration of cell clearance

ERC-2017-StG_CoSpaDD: Competition for space in development and disease

Survival of the Fittest: Essential Roles of Cell Competition in Development, Aging, and Cancer

Quantitative biology

Tissue Crowding Induces Caspase-Dependent Competition for Space.

How to be in a good shape? The influence of clone morphology on cell competition

Cell mixing induced by myc is required for competitive tissue invasion and destruction

Developmental and Stem Cell Biology

Oscillation and polarity of E-cadherin asymmetries control actomyosin flow patterns during morphogenesis

Mechanisms of cell competition: themes and variations

[Regulation of intercellular adhesion during epithelial morphogenesis]

Biomechanical regulation of contractility: spatial control and dynamics

Spatial regulation of Dia and Myosin-II by RhoGEF2 controls initiation of E-cadherin endocytosis during epithelial morphogenesis

Breaking down EMT