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© Pierre Gounon
Entrée de Listeria dans une cellule épithéliale (Grossissement X 10000). Image colorisée.

About

Pascale Cossart has since 1986 investigated how bacterial pathogens interact with mammalian cells during infection. She has pioneered and documented in details how bacteria by using a multitude of complementary strategies, – including posttranslational modifications, epigenetic modifications and innate immunity mechanisms -enter into non-phagocytic cells and multiply therein, move intra-and intercellularly, and counteract the arsenal of host cell defenses. Her seminal investigations on the bacterial pathogen Listeria monocytogenes -that she has raised as a model and one of the best studied intracellular pathogens –, have paved the way to laboratories studying bacterial infectious diseases throughout the world. Her contributions encompass infection biology, cell biology, functional genomics and fundamental microbiology, including RNA-mediated regulations.

Pascale Cossart regularly organizes or co-organizes international meetings and courses and also events and tools for the general public,  contributing to the Renaissance of Microbiology internationally.

Present Positions

  • 2016 – Present | Secrétaire Perpétuel de l’Académie des Sciences
  • Emeritus Professor at the Pasteur Institute

 Previous Positions

  • 1991 – 2019 | Head of the Bacteria-Cell Interactions Unit, Institut Pasteur, Paris
  • 2006 – 2019 Professeur de Classe Exceptionnelle à l’Institut Pasteur, Paris
  • 1997 – 2005 Professeur à l’Institut Pasteur, Paris
  • 1988 – 1996 Chef de Laboratoire à l’Institut Pasteur, Paris
  • 1980 – 1987 | Chargée de Recherches à l’Institut Pasteur, Paris
  • 1976 – 1979 Assistante à l’Institut Pasteur, Paris
  • 1974 – 1975 | Professeur de Biochimie à l’École Royale de Médecine, Vientiane, Laos
  • 1972 – 1974 Boursière de la Fondation Roux. Institut Pasteur, Paris
  • 1972 – 1972 Boursière de la Fondation Philippe. Institut Pasteur, Paris
  • 1970 – 1971 University fellow à Georgetown University, Washington D. C.
  • 1969 – 1970 Assistante à l’IUT de Biologie appliquée de Lille

Fields of Scholarship

  • Infection biology, cell biology, epigenetics, fundamental microbiology

Honours and Awards

  • 1995 EMBO member
  • 1995 UNESCO Prize “Carlos Finlay”
  • 1997 | Louis Rapkine Medal, Paris, France
  • 1998 L’Oreal/UNESCO Award for Women in Science, Paris, France
  • 1998 Richard Lounsbery Prize, Académie des Sciences, Paris/National Academy of Sciences, USA
  • 1998 Academia Europae member
  • 1998 Chevalier de la Légion d’honneur, France
  • 1999 Corresponding member of the French Académie des Sciences, Paris, France
  • 2000 NESTLE Prize “L’homme et sa nutrition”
  • 2000 Louis Pasteur Gold Medal, Swedish Society of Medicine, Stockholm, Sweden
  • 2000-2017 Howard Hughes Medical Institute, International Research Scholar
  • 2001 Member of the “Deutsche Akademie der Naturforscher Leopoldina”, Halle, Germany
  • 2002 Member of the French Académie des Sciences, Paris, France
  • 2002 Officier de l’Ordre National du Mérite, France
  • 2003 Valade Senior Prize, Fondation de France, Paris, France
  • 2003 -2012 Member of the CCNE (Comité Consultatif National d’Ethique)
  • 2004 Member of the Academy of Microbiology
  • 2005 INSERM Prize of Fundamental Research, Paris, France
  • 2006 Médaille prestige de l’Institut Cochin, Paris, France
  • 2007 GLAXO SMITH KLINE International Member of the Year Award, ASM, Toronto, Canada
  • 2007 | Robert Koch Prize, Berlin, Germany
  • 2007 Officier de la Legion d’honneur, France
  • 2008 René Descartes Prize (2008) for collaborative transnational research, Brussel, Belgium
  • 2008 Louis Jeantet Prize for Medicine, Geneva, Switzerland
  • 2008 ERC Advanced Grant Award
  • 2009 Member of the European Academy of Microbiology
  • 2009 Member of the American National Academy of Sciences, USA
  • 2009 Doctor honoris causa, École Polytechnique Fédérale de Lausanne, Switzerland
  • 2010 Robert Koch Medal of the Robert Koch Institute, Berlin, Germany
  • 2010 Foreign Member of the Royal Society (ForMemRS), London, UK
  • 2010 Commandeur de l’Ordre Nationale du Mérite, France
  • 2011 Van Deenen Medal of the Institute of Biomembranes, Utrecht, Netherlands
  • 2013 Hemoltz International Fellow Award, Berlin, Germany
  • 2013 | Balzan Prize, Milan, Italy
  • 2013 H.P.R. Seelinger Award, Wurzburg, Germany
  • 2014 Foreign Member of the National Academy of Medicine, USA
  • 2014 |FEBS, EMBO Women in Science
  • 2014 Jürgen Manchot-Guest Professorship, Düsseldorf, Germany
  • 2015 ERC Advanced Grant Award
  • 2015 Doctor honoris causa of the University of Birmingham, United Kingdom
  • 2016 Secrétaire Perpétuel de l’Académie des Sciences
  • 2016 Associate Member of the Académie Nationale de Pharmacie, Paris, France
  • 2017 Ernst Jung Gold Medal for Medicine, Hamburg, Germany
  • 2018 Prix René et Andrée Duquesne, Paris, France
  • 2018 Heinrich Wieland Prize, Munich, Germany
  • 2019 FEMS-Lwoff Award, Glasgow, UK
  • 2020 Doctor honoris causa of the Karolinska Insitute, Stockholm, Sweden

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Publications

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